2WB5

GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation

Summary for 2WB5

Entry DOI	10.2210/pdb2wb5/pdb
Related	2J62 2JH2 2V5C 2V5D 2VUR
Descriptor	O-GLCNACASE NAGJ, CHLORIDE ION, SODIUM ION, ... (5 entities in total)
Functional Keywords	hydrolase, glycosidase
Biological source	CLOSTRIDIUM PERFRINGENS
Total number of polymer chains	2
Total formula weight	134300.50
Authors	Dorfmueller, H.C.,Borodkin, V.S.,Schimpl, M.,van Aalten, D.M.F. (deposition date: 2009-02-20, release date: 2009-03-31, Last modification date: 2023-12-13)
Primary citation	Dorfmueller, H.C.,Borodkin, V.S.,Schimpl, M.,Van Aalten, D.M.F. Glcnacstatins are Nanomolar Inhibitors of Human O-Glcnacase Inducing Cellular Hyper-O-Glcnacylation Biochem.J., 420:221-, 2009 Cited by PubMed: 19275764 DOI: 10.1042/BJ20090110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.31 Å)

Structure validation