2VUR

Chemical dissection of the link between Streptozotocin, O-GlcNAc and pancreatic cell death

Summary for 2VUR

Entry DOI	10.2210/pdb2vur/pdb
Related	2J62 2JH2 2V5C 2V5D
Descriptor	O-GLCNACASE NAGJ, 2-deoxy-2-{[(2-hydroxy-1-methylhydrazino)carbonyl]amino}-beta-D-glucopyranose, SULFATE ION, ... (4 entities in total)
Functional Keywords	hydrolase, streptozotocin (stz), o-glcnac hydrolase (oga), glycosidase
Biological source	CLOSTRIDIUM PERFRINGENS
Total number of polymer chains	2
Total formula weight	134007.96
Authors	Pathak, S.,Dorfmueller, H.C.,Borodkin, V.S.,van Aalten, D.M.F. (deposition date: 2008-05-29, release date: 2009-02-10, Last modification date: 2020-07-29)
Primary citation	Pathak, S.,Dorfmueller, H.C.,Borodkin, V.S.,Van Aalten, D.M.F. Chemical Dissection of the Link between Streptozotocin, O-Glcnac, and Pancreatic Cell Death. Chem.Biol., 15:799-, 2008 Cited by PubMed: 18721751 DOI: 10.1016/J.CHEMBIOL.2008.06.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation