4V9S
 
 | | Crystal structure of antibiotic GE82832 bound to 70S ribosome | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | | 著者 | Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. | | 登録日 | 2013-12-05 | | 公開日 | 2014-07-09 | | 最終更新日 | 2018-06-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep, 6, 2014
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4F5J
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3KX3
 | | Crystal structure of Bacillus megaterium BM3 heme domain mutant L86E | | 分子名称: | Bifunctional P-450/NADPH-P450 reductase, N-PALMITOYLGLYCINE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Girvan, H.M, Levy, C.W, Leys, D, Munro, A.W. | | 登録日 | 2009-12-02 | | 公開日 | 2010-05-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | | 主引用文献 | Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3.
Biochem.J., 427, 2010
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1HZ9
 | | BACILLUS CALDOLYTICUS COLD-SHOCK PROTEIN MUTANTS TO STUDY DETERMINANTS OF PROTEIN STABILITY | | 分子名称: | COLD SHOCK PROTEIN CSPB | | 著者 | Delbrueck, H, Mueller, U, Perl, D, Schmid, F.X, Heinemann, U. | | 登録日 | 2001-01-24 | | 公開日 | 2001-11-07 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of mutant forms of the Bacillus caldolyticus cold shock protein differing in thermal stability.
J.Mol.Biol., 313, 2001
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4EZA
 | | Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2 | | 分子名称: | Ras GTPase-activating-like protein IQGAP2 | | 著者 | Van Aalten, D.M.F, Dixon, M.J, Gray, A, Schenning, M, Agacan, M, Leslie, N.R, Downes, C.P, Batty, I.H, Nedyalkova, L, Tempel, W, Tong, Y, Zhong, N, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2012-05-02 | | 公開日 | 2012-05-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold.
J.Biol.Chem., 287, 2012
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1HZA
 | | BACILLUS CALDOLYTICUS COLD-SHOCK PROTEIN MUTANTS TO STUDY DETERMINANTS OF PROTEIN STABILITY | | 分子名称: | COLD SHOCK PROTEIN CSPB | | 著者 | Delbrueck, H, Mueller, U, Perl, D, Schmid, F.X, Heinemann, U. | | 登録日 | 2001-01-24 | | 公開日 | 2001-11-07 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of mutant forms of the Bacillus caldolyticus cold shock protein differing in thermal stability.
J.Mol.Biol., 313, 2001
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7RCP
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6QY3
 | | Segment of the Cas1-Cas2-Csn2-DNA filament complex from the Type II-A CRISPR-Cas system | | 分子名称: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | | 著者 | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | | 登録日 | 2019-03-08 | | 公開日 | 2019-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (9.1 Å) | | 主引用文献 | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System.
Mol.Cell, 75, 2019
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1VYQ
 | | Novel inhibitors of Plasmodium Falciparum dUTPase provide a platform for anti-malarial drug design | | 分子名称: | 2,3-DEOXY-3-FLUORO-5-O-TRITYLURIDINE, DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE | | 著者 | Whittingham, J.L, Leal, I, Kasinathan, G, Nguyen, C, Bell, E, Jones, A.F, Berry, C, Benito, A, Turkenburg, J.P, Dodson, E.J, Ruiz Perez, L.M, Wilkinson, A.J, Johansson, N.G, Brun, R, Gilbert, I.H, Gonzalez Pacanowska, D, Wilson, K.S. | | 登録日 | 2004-05-05 | | 公開日 | 2005-05-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Dutpase as a Platform for Antimalarial Drug Design: Structural Basis for the Selectivity of a Class of Nucleoside Inhibitors.
Structure, 13, 2005
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1HZB
 | | BACILLUS CALDOLYTICUS COLD-SHOCK PROTEIN MUTANTS TO STUDY DETERMINANTS OF PROTEIN STABILITY | | 分子名称: | COLD SHOCK PROTEIN CSPB, SODIUM ION | | 著者 | Delbrueck, H, Mueller, U, Perl, D, Schmid, F.X, Heinemann, U. | | 登録日 | 2001-01-24 | | 公開日 | 2001-11-07 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | Crystal structures of mutant forms of the Bacillus caldolyticus cold shock protein differing in thermal stability.
J.Mol.Biol., 313, 2001
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1HZC
 | | BACILLUS CALDOLYTICUS COLD-SHOCK PROTEIN MUTANTS TO STUDY DETERMINANTS OF PROTEIN STABILITY | | 分子名称: | COLD SHOCK PROTEIN CSPB, SODIUM ION | | 著者 | Delbrueck, H, Mueller, U, Perl, D, Schmid, F.X, Heinemann, U. | | 登録日 | 2001-01-24 | | 公開日 | 2001-11-07 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Crystal structures of mutant forms of the Bacillus caldolyticus cold shock protein differing in thermal stability.
J.Mol.Biol., 313, 2001
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8S9D
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4F4M
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3L2Z
 | | Crystal structure of hydrated Biotin Protein Ligase from M. tuberculosis | | 分子名称: | BirA bifunctional protein | | 著者 | Gupta, V, Gupta, R.K, Khare, G, Salunke, D.M, Tyagi, A.K. | | 登録日 | 2009-12-16 | | 公開日 | 2010-03-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural ordering of disordered ligand-binding loops of biotin protein ligase into active conformations as a consequence of dehydration.
Plos One, 5, 2010
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4F5F
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5L53
 | | Menthone neomenthol reductase from Mentha piperita in complex with NADP | | 分子名称: | (-)-menthone:(+)-neomenthol reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S. | | 登録日 | 2016-05-27 | | 公開日 | 2016-08-31 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases.
Angew.Chem.Int.Ed.Engl., 55, 2016
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3KHD
 | | Crystal Structure of PFF1300w. | | 分子名称: | Pyruvate kinase | | 著者 | Wernimont, A.K, Hutchinson, A, Hassanali, A, Mackenzie, F, Cossar, D, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Pizarro, J.C, Bakszt, R, Hills, T, Structural Genomics Consortium (SGC) | | 登録日 | 2009-10-30 | | 公開日 | 2010-01-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structure of PFF1300w.
To be Published
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2G0J
 | | Crystal structure of SMU.848 from Streptococcus mutans | | 分子名称: | hypothetical protein SMU.848 | | 著者 | Hou, H.-F, Gao, Z.-Q, Li, L.-F, Liang, Y.-H, Su, X.-D, Dong, Y.-H. | | 登録日 | 2006-02-13 | | 公開日 | 2006-08-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of SMU.848 from Streptococcus mutans
To be Published
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2FMO
 | | Ala177Val mutant of E. coli Methylenetetrahydrofolate Reductase | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5,10-methylenetetrahydrofolate reductase, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Pejchal, R, Campbell, E, Guenther, B.D, Lennon, B.W, Matthews, R.G, Ludwig, M.L. | | 登録日 | 2006-01-09 | | 公開日 | 2006-04-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural Perturbations in the Ala -> Val Polymorphism of Methylenetetrahydrofolate Reductase: How Binding of Folates May Protect against Inactivation
Biochemistry, 45, 2006
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5L8V
 | | Apo-structure of humanised RadA-mutant humRadA4 | | 分子名称: | DNA repair and recombination protein RadA, PHOSPHATE ION | | 著者 | Marsh, M, Fischer, G, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M. | | 登録日 | 2016-06-08 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
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4F2E
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2FN2
 | | SOLUTION NMR STRUCTURE OF THE GLYCOSYLATED SECOND TYPE TWO MODULE OF FIBRONECTIN, 20 STRUCTURES | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FIBRONECTIN | | 著者 | Sticht, H, Pickford, A.R, Potts, J.R, Campbell, I.D. | | 登録日 | 1997-08-06 | | 公開日 | 1998-09-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the glycosylated second type 2 module of fibronectin.
J.Mol.Biol., 276, 1998
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5LB4
 | | Apo-structure of humanised RadA-mutant humRadA14 | | 分子名称: | DNA repair and recombination protein RadA | | 著者 | Marsh, M, Fischer, G, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M. | | 登録日 | 2016-06-15 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51.
J.Mol.Biol., 428, 2016
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7RKC
 | | Computationally designed tunable C2 symmetric tandem repeat homodimer, D_3_633 | | 分子名称: | ACETATE ION, D_3_633 | | 著者 | Kennedy, M.A, Stoddard, B.L, Hicks, D.R, Bera, A.K. | | 登録日 | 2021-07-22 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | De novo design of protein homodimers containing tunable symmetric protein pockets.
Proc.Natl.Acad.Sci.USA, 119, 2022
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4F4L
 | | Open Channel Conformation of a Voltage Gated Sodium Channel | | 分子名称: | Ion transport protein | | 著者 | McCusker, E.C, Bagneris, C, Naylor, C.E, Cole, A.R, D'Avanzo, N, Nichols, C.G, Wallace, B.A. | | 登録日 | 2012-05-10 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | | 主引用文献 | Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing.
Nat Commun, 3, 2012
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