6MB4
 
 | | Binary (sisomicin) structure of AAC-IIIb | | Descriptor: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, Aac(3)-IIIb protein | | Authors: | Cuneo, M.J, Kumar, P. | | Deposit date: | 2018-08-29 | | Release date: | 2018-11-07 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.302 Å) | | Cite: | Encoding of Promiscuity in an Aminoglycoside Acetyltransferase.
J. Med. Chem., 61, 2018
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6MB6
 | | AAC-IIIb binary with CoASH | | Descriptor: | Aac(3)-IIIb protein, COENZYME A, MALONATE ION | | Authors: | Cuneo, M.J, Kumar, P. | | Deposit date: | 2018-08-29 | | Release date: | 2018-11-07 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Encoding of Promiscuity in an Aminoglycoside Acetyltransferase.
J. Med. Chem., 61, 2018
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6DTT
 | | Apo T. maritima MalE2 | | Descriptor: | maltose-binding protein MalE2 | | Authors: | Cuneo, M.J, Shukla, S. | | Deposit date: | 2018-06-18 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Differential Substrate Recognition by Maltose Binding Proteins Influenced by Structure and Dynamics.
Biochemistry, 57, 2018
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2GHB
 | | Thermotoga maritima maltotriose binding protein, ligand free form | | Descriptor: | maltose ABC transporter, periplasmic maltose-binding protein | | Authors: | Cuneo, M.J, Changela, A, Hocker, B, Beese, L.S, Hellinga, H.W. | | Deposit date: | 2006-03-27 | | Release date: | 2007-02-06 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | T. maritima maltotriose binding protein open form
To be Published
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2GH9
 | | Thermus thermophilus maltotriose binding protein bound with maltotriose | | Descriptor: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose/maltodextrin-binding protein | | Authors: | Cuneo, M.J, Changela, A, Beese, L.S, Hellinga, H.W. | | Deposit date: | 2006-03-27 | | Release date: | 2007-02-06 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural adaptations that modulate monosaccharide, disaccharide, and trisaccharide specificities in periplasmic maltose-binding proteins.
J.Mol.Biol., 389, 2009
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2GHA
 | | Thermotoga maritima maltotriose binding protein bound with maltotriose | | Descriptor: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose ABC transporter, periplasmic maltose-binding protein | | Authors: | Cuneo, M.J, Changela, A, Hocker, B, Beese, L.S, Hellinga, H.W. | | Deposit date: | 2006-03-27 | | Release date: | 2007-02-06 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | T. maritima maltotriose binding protein
To be Published
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6DTR
 | | Apo T. maritima MalE3 | | Descriptor: | SULFATE ION, maltose-binding protein MalE3 | | Authors: | Cuneo, M.J, Shukla, S. | | Deposit date: | 2018-06-18 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.301 Å) | | Cite: | Differential Substrate Recognition by Maltose Binding Proteins Influenced by Structure and Dynamics.
Biochemistry, 57, 2018
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6DTS
 | | Maltotetraose bound T. maritima MalE2 | | Descriptor: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose-binding protein MalE2 | | Authors: | Cuneo, M.J, Shukla, S. | | Deposit date: | 2018-06-18 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Differential Substrate Recognition by Maltose Binding Proteins Influenced by Structure and Dynamics.
Biochemistry, 57, 2018
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6DTU
 | | Maltotetraose bound T. maritima MalE1 | | Descriptor: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose-binding protein MalE1 | | Authors: | Cuneo, M.J, Shukla, S. | | Deposit date: | 2018-06-18 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Differential Substrate Recognition by Maltose Binding Proteins Influenced by Structure and Dynamics.
Biochemistry, 57, 2018
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3C6Q
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2O7I
 | | The X-ray crystal structure of a thermophilic cellobiose binding protein bound with cellobiose | | Descriptor: | Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | Authors: | Cuneo, M.J, Hellinga, H.W. | | Deposit date: | 2006-12-11 | | Release date: | 2007-03-20 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural Analysis of Semi-specific Oligosaccharide Recognition by a Cellulose-binding Protein of Thermotoga maritima Reveals Adaptations for Functional Diversification of the Oligopeptide Periplasmic Binding Protein Fold.
J.Biol.Chem., 284, 2009
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6UN8
 | | Wild type ANT bound to neomycin | | Descriptor: | Aminoglycoside NucleotidylTransferase, MAGNESIUM ION, NEOMYCIN | | Authors: | Cuneo, M.J, Selvaraj, B. | | Deposit date: | 2019-10-11 | | Release date: | 2020-05-06 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | "Catch and Release": a Variation of the Archetypal NucleotidylTransfer Reaction
ACS Catal, 10, 2020
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5EAJ
 | | Crystal structure of DHFR in 0% Isopropanol | | Descriptor: | CALCIUM ION, CHLORIDE ION, Dihydrofolate reductase, ... | | Authors: | Cuneo, M.J, Agarwal, P.K. | | Deposit date: | 2015-10-16 | | Release date: | 2016-09-21 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.701 Å) | | Cite: | Modulating Enzyme Activity by Altering Protein Dynamics with Solvent.
Biochemistry, 57, 2018
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3PC7
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3PC6
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3PC8
 | | X-ray crystal structure of the heterodimeric complex of XRCC1 and DNA ligase III-alpha BRCT domains. | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA ligase 3, DNA repair protein XRCC1, ... | | Authors: | Cuneo, M.J, Krahn, J.M, London, R.E. | | Deposit date: | 2010-10-21 | | Release date: | 2011-06-15 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | The structural basis for partitioning of the XRCC1/DNA ligase III-{alpha} BRCT-mediated dimer complexes.
Nucleic Acids Res., 39, 2011
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3QVG
 | | XRCC1 bound to DNA ligase | | Descriptor: | DNA ligase 3, DNA repair protein XRCC1 | | Authors: | Cuneo, M.J, Krahn, J.M, London, R.E. | | Deposit date: | 2011-02-25 | | Release date: | 2011-06-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | The structural basis for partitioning of the XRCC1/DNA ligase III-{alpha} BRCT-mediated dimer complexes.
Nucleic Acids Res., 39, 2011
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8DHD
 | | Neutron crystal structure of maltotetraose bound tmMBP | | Descriptor: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose-binding protein MalE2 | | Authors: | Cuneo, M.J, Shukla, S, Myles, D.A. | | Deposit date: | 2022-06-27 | | Release date: | 2022-10-12 | | Last modified: | 2023-10-25 | | Method: | NEUTRON DIFFRACTION (1.7 Å), X-RAY DIFFRACTION | | Cite: | Mapping periplasmic binding protein oligosaccharide recognition with neutron crystallography.
Sci Rep, 12, 2022
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3K75
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3K77
 | | X-ray crystal structure of XRCC1 | | Descriptor: | DNA repair protein XRCC1 | | Authors: | Cuneo, M.J, London, R.E. | | Deposit date: | 2009-10-12 | | Release date: | 2010-04-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.597 Å) | | Cite: | Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3I5O
 | | The X-ray crystal structure of a thermophilic cellobiose binding protein bound with cellopentaose | | Descriptor: | Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | Authors: | Cuneo, M.J, Hellinga, H.W. | | Deposit date: | 2009-07-06 | | Release date: | 2009-07-21 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural Analysis of Semi-specific Oligosaccharide Recognition by a Cellulose-binding Protein of Thermotoga maritima Reveals Adaptations for Functional Diversification of the Oligopeptide Periplasmic Binding Protein Fold.
J.Biol.Chem., 284, 2009
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3LQC
 | | X-ray crystal structure of oxidized XRCC1 bound to DNA pol beta Palm thumb domain | | Descriptor: | CARBONATE ION, DNA polymerase beta, DNA repair protein XRCC1, ... | | Authors: | Cuneo, M.J, Krahn, J.M, London, R.E. | | Deposit date: | 2010-02-09 | | Release date: | 2010-04-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.349 Å) | | Cite: | Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.
Proc.Natl.Acad.Sci.USA, 107, 2010
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6U0F
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6U0E
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6U0B
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