5EAJ
Crystal structure of DHFR in 0% Isopropanol
Summary for 5EAJ
Entry DOI | 10.2210/pdb5eaj/pdb |
Related | 5E8Q |
Descriptor | Dihydrofolate reductase, FOLIC ACID, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | dynamics, oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 37105.34 |
Authors | Cuneo, M.J.,Agarwal, P.K. (deposition date: 2015-10-16, release date: 2016-09-21, Last modification date: 2023-09-27) |
Primary citation | Duff Jr., M.R.,Borreguero, J.M.,Cuneo, M.J.,Ramanathan, A.,He, J.,Kamath, G.,Chennubhotla, S.C.,Meilleur, F.,Howell, E.E.,Herwig, K.W.,Myles, D.A.A.,Agarwal, P.K. Modulating Enzyme Activity by Altering Protein Dynamics with Solvent. Biochemistry, 57:4263-4275, 2018 Cited by PubMed: 29901984DOI: 10.1021/acs.biochem.8b00424 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.701 Å) |
Structure validation
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