AAC-IIIb binary with CoASH

Summary for 6MB6

DescriptorAac(3)-IIIb protein, COENZYME A, MALONATE ION, ... (4 entities in total)
Functional Keywordsacetyltransferase, promiscuity, gnat, antibiotic resistance, transferase
Biological sourcePseudomonas aeruginosa
Total number of polymer chains4
Total molecular weight117814.36
Cuneo, M.J.,Kumar, P. (deposition date: 2018-08-29, release date: 2018-11-07, Last modification date: 2018-12-05)
Primary citation
Kumar, P.,Selvaraj, B.,Serpersu, E.H.,Cuneo, M.J.
Encoding of Promiscuity in an Aminoglycoside Acetyltransferase.
J. Med. Chem., 61:10218-10227, 2018
PubMed: 30347146 (PDB entries with the same primary citation)
DOI: 10.1021/acs.jmedchem.8b01393
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2465 0.3% 1.9% 3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6mb6
no rotation
Molmil generated image of 6mb6
rotated about x axis by 90°
Molmil generated image of 6mb6
rotated about y axis by 90°
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2019 Protein Data Bank Japan