PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Reversible lysine-targeted probes reveal residence time-based kinase selectivity in vivo
Descriptor:	6-[(5-cyclopropyl-1~{H}-pyrazol-3-yl)amino]-2-[4-[(3-methyl-4-oxidanyl-phenyl)methyl]piperazin-1-yl]-~{N}-prop-2-ynyl-pyrimidine-4-carboxamide, Aurora kinase A, CHLORIDE ION
Authors:	Craven, G.B, Wan, X.B, Taunton, J.
Deposit date:	2021-07-31
Release date:	2022-06-08
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.32 Å)
Cite:	Reversible lysine-targeted probes reveal residence time-based kinase selectivity. Nat.Chem.Biol., 18, 2022

WDR5 covalently modified at Y228 by (R)-2-SF
Descriptor:	3-ethynyl-5-{[(3R)-4-{1-[(2-methoxyphenyl)methyl]-1H-benzimidazole-5-carbonyl}-3-methylpiperazin-1-yl]methyl}benzene-1-sulfonyl fluoride, CHLORIDE ION, GLYCEROL, ...
Authors:	Taunton, J, Craven, G.B, Chen, Y.
Deposit date:	2022-11-23
Release date:	2023-05-31
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes. Nat.Chem., 15, 2023