8UW2
Structure of AKT1(E17K) with compound 3 (zinc-free)
Summary for 8UW2
Entry DOI | 10.2210/pdb8uw2/pdb |
Related | 8UVY |
Descriptor | RAC-alpha serine/threonine-protein kinase, NB41, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | inhibitor, kinase, transferase, transferase-inhibitor complex, transferase/inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 66307.19 |
Authors | |
Primary citation | Craven, G.B.,Taunton, J. Mutant-selective AKT1 inhibitors via lysine targeting and neo-zinc chelation To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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