8UW9
Structure of AKT1(E17K) with compound 4
Summary for 8UW9
Entry DOI | 10.2210/pdb8uw9/pdb |
Related | 8UVY 8UW2 8UW7 |
Descriptor | RAC-alpha serine/threonine-protein kinase, NB41, N-({4-[(2P)-2-(2-aminopyridin-3-yl)-5-phenyl-3H-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)-2-(2-fluoro-4-formyl-3-hydroxyphenyl)acetamide, ... (8 entities in total) |
Functional Keywords | inhibitor, kinase, transferase, transferase-inhibitor complex, transferase/inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 66309.97 |
Authors | |
Primary citation | Craven, G.B.,Taunton, J. Mutant-selective AKT1 inhibitors via lysine targeting and neo-zinc chelation To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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