1I3Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1i3q by Molmil](/molmil-images/mine/1i3q) | RNA POLYMERASE II CRYSTAL FORM I AT 3.1 A RESOLUTION | Descriptor: | DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE, ... | Authors: | Cramer, P, Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2001-02-15 | Release date: | 2001-04-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution. Science, 292, 2001
|
|
1I50
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1i50 by Molmil](/molmil-images/mine/1i50) | RNA POLYMERASE II CRYSTAL FORM II AT 2.8 A RESOLUTION | Descriptor: | DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE, ... | Authors: | Cramer, P, Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2001-02-23 | Release date: | 2001-04-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution. Science, 292, 2001
|
|
1A3Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1a3q by Molmil](/molmil-images/mine/1a3q) | HUMAN NF-KAPPA-B P52 BOUND TO DNA | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*AP*TP*TP*CP*CP*CP*C)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B P52) | Authors: | Cramer, P, Larson, C.J, Verdine, G.L, Muller, C.W. | Deposit date: | 1998-01-23 | Release date: | 1998-06-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution. EMBO J., 16, 1997
|
|
1Y1W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y1w by Molmil](/molmil-images/mine/1y1w) | Complete RNA Polymerase II elongation complex | Descriptor: | 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*AP*T)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ... | Authors: | Cramer, P, Kettenberger, H, Armache, K.-J. | Deposit date: | 2004-11-19 | Release date: | 2005-01-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS Mol.Cell, 16, 2004
|
|
1Y1Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y1y by Molmil](/molmil-images/mine/1y1y) | RNA Polymerase II-TFIIS-DNA/RNA complex | Descriptor: | 5'-D(P*TP*AP*CP*GP*CP*CP*T)-3', 5'-R(P*AP*GP*GP*C)-3', DNA-directed RNA polymerase II 13.6 kDa polypeptide, ... | Authors: | Cramer, P, Kettenberger, H, Armache, K.-J. | Deposit date: | 2004-11-19 | Release date: | 2004-12-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS. Mol.Cell, 16, 2004
|
|
1BVO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bvo by Molmil](/molmil-images/mine/1bvo) | DORSAL HOMOLOGUE GAMBIF1 BOUND TO DNA | Descriptor: | DNA DUPLEX, TRANSCRIPTION FACTOR GAMBIF1 | Authors: | Cramer, P, Varrot, A, Barillas-Mury, C, Kafatos, F.C, Mueller, C.W. | Deposit date: | 1998-09-16 | Release date: | 1999-07-12 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of the specificity domain of the Dorsal homologue Gambif1 bound to DNA. Structure Fold.Des., 7, 1999
|
|
5IP7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ip7 by Molmil](/molmil-images/mine/5ip7) | Structure of RNA Polymerase II-Tfg1 peptide complex | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P. | Deposit date: | 2016-03-09 | Release date: | 2016-05-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.52 Å) | Cite: | Transcription initiation complex structures elucidate DNA opening. Nature, 533, 2016
|
|
8BYQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8byq by Molmil](/molmil-images/mine/8byq) | RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W) | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. | Deposit date: | 2022-12-14 | Release date: | 2023-05-03 | Last modified: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Mol.Cell, 83, 2023
|
|
2RF4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2rf4 by Molmil](/molmil-images/mine/2rf4) | |
2R93
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2r93 by Molmil](/molmil-images/mine/2r93) | Elongation complex of RNA polymerase II with a hepatitis delta virus-derived RNA stem loop | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Lehmann, E, Brueckner, F, Cramer, P. | Deposit date: | 2007-09-12 | Release date: | 2007-11-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Molecular basis of RNA-dependent RNA polymerase II activity. Nature, 450, 2007
|
|
7NKY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nky by Molmil](/molmil-images/mine/7nky) | RNA Polymerase II-Spt4/5-nucleosome-FACT structure | Descriptor: | Chromatin elongation factor SPT4, DNA (138-MER), DNA (148-MER), ... | Authors: | Farnung, L, Ochmann, M, Engeholm, M, Cramer, P. | Deposit date: | 2021-02-19 | Release date: | 2021-07-07 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of nucleosome transcription mediated by Chd1 and FACT. Nat.Struct.Mol.Biol., 28, 2021
|
|
4YM7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ym7 by Molmil](/molmil-images/mine/4ym7) | RNA polymerase I structure with an alternative dimer hinge | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Kostrewa, D, Kuhn, C.-D, Engel, C, Cramer, P. | Deposit date: | 2015-03-06 | Release date: | 2015-09-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (5.5 Å) | Cite: | An alternative RNA polymerase I structure reveals a dimer hinge. Acta Crystallogr.,Sect.D, 71, 2015
|
|
5CE7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ce7 by Molmil](/molmil-images/mine/5ce7) | Structure of a non-canonical CID of Ctk3 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CTD kinase subunit gamma | Authors: | Muehlbacher, W, Mayer, A, Sun, M, Remmert, M, Cheung, A.C, Niesser, J, Soeding, J, Cramer, P. | Deposit date: | 2015-07-06 | Release date: | 2015-08-05 | Last modified: | 2015-09-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a noncanonical CTD-interacting domain fold. Proteins, 83, 2015
|
|
4V1N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v1n by Molmil](/molmil-images/mine/4v1n) | Architecture of the RNA polymerase II-Mediator core transcription initiation complex | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | Authors: | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | Deposit date: | 2014-09-29 | Release date: | 2015-02-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
|
|
4V1O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v1o by Molmil](/molmil-images/mine/4v1o) | Architecture of the RNA polymerase II-Mediator core transcription initiation complex | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | Authors: | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | Deposit date: | 2014-09-29 | Release date: | 2015-02-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
|
|
4V1M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v1m by Molmil](/molmil-images/mine/4v1m) | Architecture of the RNA polymerase II-Mediator core transcription initiation complex | Descriptor: | 5'-D(*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-D(*CP*CP*AP*GP*GP*AP)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP*TP*TP*CP *CP*BRUP*GP*GP*TP*C)-3', ... | Authors: | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | Deposit date: | 2014-09-29 | Release date: | 2015-02-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
|
|
6I84
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6i84 by Molmil](/molmil-images/mine/6i84) | Structure of transcribing RNA polymerase II-nucleosome complex | Descriptor: | DNA (158-MER), DNA (170-MER), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Farnung, L, Vos, S.M, Cramer, P. | Deposit date: | 2018-11-19 | Release date: | 2019-01-02 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structure of transcribing RNA polymerase II-nucleosome complex. Nat Commun, 9, 2018
|
|
1PQV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pqv by Molmil](/molmil-images/mine/1pqv) | RNA polymerase II-TFIIS complex | Descriptor: | DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ... | Authors: | Kettenberger, H, Armache, K.-J, Cramer, P. | Deposit date: | 2003-06-19 | Release date: | 2003-08-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Architecture of the RNA Polymerase II-TFIIS Complex and Implications for mRNA Cleavage Cell(Cambridge,Mass.), 114, 2003
|
|
6RIE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rie by Molmil](/molmil-images/mine/6rie) | Structure of Vaccinia Virus DNA-dependent RNA polymerase co-transcriptional capping complex | Descriptor: | DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ... | Authors: | Hillen, H.S, Bartuli, J, Grimm, C, Dienemann, C, Bedenk, K, Szalar, A, Fischer, U, Cramer, P. | Deposit date: | 2019-04-23 | Release date: | 2019-12-18 | Last modified: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes. Cell, 179, 2019
|
|
6RID
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rid by Molmil](/molmil-images/mine/6rid) | Structure of Vaccinia Virus DNA-dependent RNA polymerase elongation complex | Descriptor: | DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ... | Authors: | Hillen, H.S, Bartuli, J, Grimm, C, Dienemann, C, Bedenk, K, Szalar, A, Fischer, U, Cramer, P. | Deposit date: | 2019-04-23 | Release date: | 2019-12-18 | Last modified: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes. Cell, 179, 2019
|
|
6RYU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ryu by Molmil](/molmil-images/mine/6ryu) | Nucleosome-CHD4 complex structure (two CHD4 copies) | Descriptor: | Chromodomain-helicase-DNA-binding protein 4,CHD4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... | Authors: | Farnung, L, Ochmann, M, Cramer, P. | Deposit date: | 2019-06-12 | Release date: | 2020-07-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. Elife, 9, 2020
|
|
6RYR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ryr by Molmil](/molmil-images/mine/6ryr) | Nucleosome-CHD4 complex structure (single CHD4 copy) | Descriptor: | Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... | Authors: | Farnung, L, Ochmann, M, Cramer, P. | Deposit date: | 2019-06-11 | Release date: | 2020-07-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. Elife, 9, 2020
|
|
6R80
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r80 by Molmil](/molmil-images/mine/6r80) | Structure of AFF4 C-terminal homology domain | Descriptor: | AF4/FMR2 family member 4 | Authors: | Chen, Y, Cramer, P. | Deposit date: | 2019-03-30 | Release date: | 2019-06-12 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization. J.Biol.Chem., 294, 2019
|
|
1I6H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1i6h by Molmil](/molmil-images/mine/1i6h) | RNA POLYMERASE II ELONGATION COMPLEX | Descriptor: | 5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3', 5'-R(P*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, ... | Authors: | Gnatt, A.L, Cramer, P, Kornberg, R.D. | Deposit date: | 2001-03-02 | Release date: | 2001-04-23 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution. Science, 292, 2001
|
|
1NT9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nt9 by Molmil](/molmil-images/mine/1nt9) | Complete 12-subunit RNA polymerase II | Descriptor: | DNA-DIRECTED RNA POLYMERASE II 13.6 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 19 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT, ... | Authors: | Armache, K.-J, Kettenberger, H, Cramer, P. | Deposit date: | 2003-01-29 | Release date: | 2003-04-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Architecture of initiation-competent 12-subunit RNA polymerase II Proc.Natl.Acad.Sci.USA, 100, 2003
|
|