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PDB: 42 件
3V5D
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HLA-A2.1 KVAELVHFL
分子名称: Beta-2-microglobulin, HIV peptide KVAELVHFL, HLA class I histocompatibility antigen, ...
著者Collins, E.J, Lee, H.Y.
登録日2011-12-16
公開日2012-12-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Prediction of conformation and immunogenicity of peptides bound to MHC molecules
To be Published
3V5K
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HLA2.1 KVAELVWFL
分子名称: Beta-2-microglobulin, GLYCEROL, HIV-based altered-peptide ligand KVAELVWFL, ...
著者Collins, E.J, Lee, H.Y.
登録日2011-12-16
公開日2012-12-19
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Prediction of Immunogenicity of altered-peptide ligands to HIV bound to MHC
To be Published
3V5H
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HLA-A2.1 KVAEIVHFL
分子名称: Beta-2-microglobulin, GLYCEROL, HIV-based altered-peptide ligand KVAEIVHFL, ...
著者Collins, E.J, Lee, H.Y.
登録日2011-12-16
公開日2012-12-05
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Prediction of immunogenicity of altered-peptide ligands for HIV therapy
To be Published
1TMC
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BU of 1tmc by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF A CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE MISSING THE ALPHA3 DOMAIN OF THE HEAVY CHAIN
分子名称: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-AW68), DECAMERIC PEPTIDE (EVAPPEYHRK)
著者Collins, E.J, Garboczi, D.N, Karpusas, M.N, Wiley, D.C.
登録日1994-12-19
公開日1995-03-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The three-dimensional structure of a class I major histocompatibility complex molecule missing the alpha 3 domain of the heavy chain.
Proc.Natl.Acad.Sci.USA, 92, 1995
2CLR
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BU of 2clr by Molmil
THREE DIMENSIONAL STRUCTURE OF A PEPTIDE EXTENDING OUT ONE END OF A CLASS I MHC BINDING SITE
分子名称: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A 0201) (ALPHA CHAIN), DECAMERIC PEPTIDE FROM CALRETICULIN
著者Collins, E.J, Garboczi, D.N, Wiley, D.C.
登録日1994-08-01
公開日1995-03-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structure of a peptide extending from one end of a class I MHC binding site.
Nature, 371, 1994
3KFY
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BU of 3kfy by Molmil
Dynamic switching and partial occupancies of a small molecule inhibitor complex of DHFR
分子名称: 5-[(4-chlorophenyl)sulfanyl]quinazoline-2,4-diamine, CALCIUM ION, Dihydrofolate reductase, ...
著者Collins, E.J, Lee, A.L, Carroll, M.J, Gromova, A.V, Miller, K.R, Singleton, S.F.
登録日2009-10-28
公開日2010-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Dynamic switching and partial occupancies of a small molecule inhibitor complex of DHFR
To be Published
3QYL
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Sensitivity of receptor internal motions to ligand binding affinity and kinetic off-rate
分子名称: (7S)-7-methyl-5,6,7,8-tetrahydroquinazoline-2,4-diamine, CALCIUM ION, CHLORIDE ION, ...
著者Collins, E.J, Lee, A.L, Carroll, M.J, Mauldin, R.V, Gromova, A.V, Singleton, S.F.
登録日2011-03-03
公開日2012-01-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Evidence for dynamics in proteins as a mechanism for ligand dissociation.
Nat.Chem.Biol., 8, 2012
3QYO
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Sensitivity of receptor internal motions to ligand binding affinity and kinetic off-rate
分子名称: CALCIUM ION, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Collins, E.J, Lee, A.L, Carroll, M.J, Mauldin, R.V, Gromova, A.V, Singleton, S.F.
登録日2011-03-03
公開日2012-01-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Evidence for dynamics in proteins as a mechanism for ligand dissociation.
Nat.Chem.Biol., 8, 2012
3R33
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Evidence for dynamic motion in proteins as a mechanism for ligand dissociation
分子名称: (6S)-6-methyl-5,6,7,8-tetrahydroquinazoline-2,4-diamine, CALCIUM ION, CHLORIDE ION, ...
著者Collins, E.J, Lee, A.L, Carroll, M.J, Mauldin, R.V, Gromova, A.V, Singleton, S.F.
登録日2011-03-15
公開日2012-01-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Evidence for dynamics in proteins as a mechanism for ligand dissociation.
Nat.Chem.Biol., 8, 2012
5DGC
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Reaction of phosphorylated CheY with imidazole 2 of 3
分子名称: BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, Chemotaxis protein CheY, ...
著者Page, S, Silversmith, R.E, Bourret, R.B, Collins, E.J.
登録日2015-08-27
公開日2016-03-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Imidazole as a Small Molecule Analogue in Two-Component Signal Transduction.
Biochemistry, 54, 2015
1LP9
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Xenoreactive complex AHIII 12.2 TCR bound to p1049/HLA-A2.1
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Buslepp, J, Wang, H, Biddison, W.E, Appella, E, Collins, E.J.
登録日2002-05-07
公開日2003-11-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A correlation between TCR Valpha docking on MHC and CD8 dependence: implications for T cell selection.
Immunity, 19, 2003
1KMI
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CRYSTAL STRUCTURE OF AN E.COLI CHEMOTAXIS PROTEIN, CHEZ
分子名称: BERYLLIUM TRIFLUORIDE ION, BICINE, Chemotaxis protein cheY, ...
著者Zhao, R, Collins, E.J, Bourret, R.B, Silversmith, R.E.
登録日2001-12-16
公開日2002-07-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure and catalytic mechanism of the E. coli chemotaxis phosphatase CheZ.
Nat.Struct.Biol., 9, 2002
1FFO
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BU of 1ffo by Molmil
CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH SYNTHETIC PEPTIDE GP33 (C9M/K1A)
分子名称: BETA-2 MICROGLOBULIN BETA CHAIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B, ...
著者Wang, B, Sharma, A, Maile, R, Saad, M, Collins, E.J, Frelinger, J.A.
登録日2000-07-25
公開日2002-12-11
最終更新日2017-02-01
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Peptidic termini play a significant role in TCR recognition.
J.Immunol., 169, 2002
1FFN
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BU of 1ffn by Molmil
CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH PEPTIDE GP33(C9M)
分子名称: BETA-2 MICROGLOBULIN, BETA CHAIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Wang, B, Sharma, A, Maile, R, Saad, M, Collins, E.J, Frelinger, J.A.
登録日2000-07-25
公開日2002-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Peptidic termini play a significant role in TCR recognition
J.IMMUNOL., 169, 2002
1FFP
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BU of 1ffp by Molmil
CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH PEPTIDE GP33 (C9M/K1S)
分子名称: BETA-2 MICROGLOBULIN BETA CHAIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B, ...
著者Wang, B, Sharma, A, Maile, R, Saad, M, Collins, E.J, Frelinger, J.A.
登録日2000-07-25
公開日2002-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Peptidic termini play a significant role in TCR recognition
J.IMMUNOL., 169, 2002
1EEY
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BU of 1eey by Molmil
Crystal Structure Determination Of HLA A2 Complexed to Peptide GP2 with the substitution (I2L/V5L/L9V)
分子名称: BETA-2-MICROGLOBULIN (LIGHT CHAIN), GP2 PEPTIDE, HLA-A2.1 MHC CLASS I (HEAVY CHAIN)
著者Sharma, A.K, Kuhns, J.J, Collins, E.J.
登録日2000-02-04
公開日2003-06-10
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Class I major histocompatibility complex anchor substitutions alter the conformation of T cell receptor contacts.
J.Biol.Chem., 276, 2001
1EEZ
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Crystal Structure Determination of HLA-A2.1 Complexed to GP2 Peptide Variant(I2L/V5L)
分子名称: BETA-2-MICROGLOBULIN (LIGHT CHAIN), GP2 PEPTIDE, HLA-A2.1 MHC CLASS I (HEAVY CHAIN)
著者Sharma, A.K, Kuhns, J.J, Collins, E.J.
登録日2000-02-04
公開日2003-06-10
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Class I major histocompatibility complex anchor substitutions alter the conformation of T cell receptor contacts.
J.Biol.Chem., 276, 2001
2AAI
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Crystallographic refinement of ricin to 2.5 Angstroms
分子名称: RICIN (A CHAIN), RICIN (B CHAIN), alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rutenber, E, Katzin, B.J, Montfort, W, Villafranca, J.E, Ernst, S.R, Collins, E.J, Mlsna, D, Monzingo, A.F, Ready, M.P, Robertus, J.D.
登録日1993-09-07
公開日1994-01-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallographic refinement of ricin to 2.5 A.
Proteins, 10, 1991
1B0G
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CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A2.1)/BETA 2-MICROGLOBULIN/PEPTIDE P1049 COMPLEX
分子名称: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN, PEPTIDE P1049 (ALWGFFPVL)
著者Zhao, R, Collins, E.J.
登録日1998-11-09
公開日1998-11-18
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural evidence of T cell xeno-reactivity in the absence of molecular mimicry.
J.Exp.Med., 189, 1999
1I7R
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CRYSTAL STRUCTURE OF CLASS I MHC A2 IN COMPLEX WITH PEPTIDE P1058
分子名称: 9 RESIDUE PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Busslep, J, Zhao, R, Loftus, D, Appella, E, Collins, E.J.
登録日2001-03-10
公開日2001-10-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献T cell activity correlates with oligomeric peptide/MHC binding on T cell surface
J.Biol.Chem., 276, 2001
1I7U
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CRYSTAL STRUCTURE OF CLASS I MHC A2 IN COMPLEX WITH PEPTIDE P1049-6V
分子名称: 9 RESIDUE PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Busslep, J, Zhao, R, Loftus, D, Appella, E, Collins, E.J.
登録日2001-03-10
公開日2001-10-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献T cell activity correlates with oligomeric peptide-major histocompatibility complex binding on T cell surface
J.Biol.Chem., 276, 2001
1I7T
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CRYSTAL STRUCTURE OF CLASS I MHC A2 IN COMPLEX WITH PEPTIDE P1049-5V
分子名称: 9 RESIDUE PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Busslep, J, Zhao, R, Loftus, D, Appella, E, Collins, E.J.
登録日2001-03-10
公開日2001-10-24
最終更新日2021-07-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献T cell activity correlates with oligomeric peptide-major histocompatibility complex binding on T cell surface
J.Biol.Chem., 276, 2001
1BZ9
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CRYSTAL STRUCTURE OF MURINE CLASS I MHC H2-DB COMPLEXED WITH A SYNTHETIC PEPTIDE P1027
分子名称: PROTEIN (CLASS I HISTOCOMPATIBILITY ANTIGEN), PROTEIN (PEPTIDE P1027 (FAPGVFPYM))
著者Zhao, R, Collins, E.J.
登録日1998-11-06
公開日1999-05-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural evidence of T cell xeno-reactivity in the absence of molecular mimicry.
J.Exp.Med., 189, 1999
1I1Y
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CRYSTAL STRUCTURE OF HUMAN CLASS I MHC (HLA-A2.1) COMPLEXED WITH BETA 2-MICROGLOBULIN AND HIV-RT VARIANT PEPTIDE I1Y
分子名称: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN, HIV-RT VARIANT PEPTIDE I1Y (YLKEPVHGV)
著者Kirksey, T.J, Collins, E.J.
登録日1999-04-16
公開日2000-01-21
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structural basis for the increased immunogenicity of two HIV-reverse transcriptase peptide variant/class I major histocompatibility complexes.
J.Biol.Chem., 274, 1999
1QR1
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POOR BINDING OF A HER-2/NEU EPITOPE (GP2) TO HLA-A2.1 IS DUE TO A LACK OF INTERACTIONS IN THE CENTER OF THE PEPTIDE
分子名称: BETA-2 MICROGLOBULIN, GP2 PEPTIDE, HLA-A2.1 HEAVY CHAIN
著者Kuhns, J.J, Batalia, M.A, Yan, S, Collins, E.J.
登録日1999-06-17
公開日2000-01-01
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Poor binding of a HER-2/neu epitope (GP2) to HLA-A2.1 is due to a lack of interactions with the center of the peptide.
J.Biol.Chem., 274, 1999

 

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