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PDB: 15 件
8QBN
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BU of 8qbn by Molmil
Structure of the non-canonical CTLH E3 substrate receptor WDR26 bound to YPEL5
分子名称: Protein yippee-like 5, WD repeat-containing protein 26, ZINC ION
著者Chrustowicz, J, Sherpa, D, Schulman, B.A.
登録日2023-08-24
公開日2024-05-15
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism.
Mol.Cell, 84, 2024
8QE8
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BU of 8qe8 by Molmil
Structure of the non-canonical CTLH E3 substrate receptor WDR26 bound to NMNAT1 substrate
分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1, WD repeat-containing protein 26, ...
著者Chrustowicz, J, Sherpa, D, Schulman, B.A.
登録日2023-08-30
公開日2024-05-15
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism.
Mol.Cell, 84, 2024
8PJN
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BU of 8pjn by Molmil
Catalytic module of human CTLH E3 ligase bound to multiphosphorylated UBE2H~ubiquitin
分子名称: E3 ubiquitin-protein transferase MAEA, E3 ubiquitin-protein transferase RMND5A, Ubiquitin, ...
著者Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A.
登録日2023-06-23
公開日2024-01-03
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.
Mol.Cell, 84, 2024
8PMQ
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BU of 8pmq by Molmil
Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin
分子名称: E3 ubiquitin-protein ligase RMD5, Protein FYV10, Ubiquitin, ...
著者Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A.
登録日2023-06-29
公開日2024-01-03
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.
Mol.Cell, 84, 2024
7NSB
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BU of 7nsb by Molmil
Supramolecular assembly module of yeast Chelator-GID SR4 E3 ubiquitin ligase
分子名称: Glucose-induced degradation protein 7, Glucose-induced degradation protein 8, Vacuolar import and degradation protein 30
著者Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A.
登録日2021-03-05
公開日2021-05-05
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
7NSC
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BU of 7nsc by Molmil
Substrate receptor scaffolding module of human CTLH E3 ubiquitin ligase
分子名称: Glucose-induced degradation protein 4 homolog, Glucose-induced degradation protein 8 homolog, Isoform 2 of Armadillo repeat-containing protein 8, ...
著者Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A.
登録日2021-03-05
公開日2021-05-05
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
7Q51
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BU of 7q51 by Molmil
yeast Gid10 bound to a Phe/N-peptide
分子名称: CHLORIDE ION, FWLPANLW peptide, Uncharacterized protein YGR066C
著者Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A.
登録日2021-11-02
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases.
J.Mol.Biol., 434, 2022
7Q50
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BU of 7q50 by Molmil
human Gid4 bound to a Phe/N-peptide
分子名称: FDVSWFMG peptide, Glucose-induced degradation protein 4 homolog
著者Chrustowicz, J, Sherpa, D, Loke, M.S, Prabu, J.R, Schulman, B.A.
登録日2021-11-02
公開日2022-03-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases.
J.Mol.Biol., 434, 2022
7QQY
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BU of 7qqy by Molmil
yeast Gid10 bound to Art2 Pro/N-degron
分子名称: CHLORIDE ION, ECM21, Uncharacterized protein YGR066C
著者Chrustowicz, J, Sherpa, D, Schulman, B.A.
登録日2022-01-10
公開日2022-03-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters.
Embo Rep., 23, 2022
6N3J
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BU of 6n3j by Molmil
MicroED Structure of the CTD-SP1 fragment of HIV-1 Gag
分子名称: CTD-SP1 fragment of HIV-1 Gag
著者Purdy, M.D, Shi, D, Hattne, J, Chrustowicz, J.
登録日2018-11-15
公開日2018-12-12
最終更新日2023-10-11
実験手法ELECTRON CRYSTALLOGRAPHY (3 Å)
主引用文献MicroED structures of HIV-1 Gag CTD-SP1 reveal binding interactions with the maturation inhibitor bevirimat.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6N3U
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BU of 6n3u by Molmil
MicroED Structure of the CTD-SP1 fragment of HIV-1 Gag with bound maturation inhibitor Bevirimat.
分子名称: CTD-SP1 fragment of HIV-1 Gag
著者Purdy, M.D, Shi, D, Hattne, J, Chrustowicz, J.
登録日2018-11-16
公開日2018-12-12
最終更新日2023-10-25
実験手法ELECTRON CRYSTALLOGRAPHY (2.9 Å)
主引用文献MicroED structures of HIV-1 Gag CTD-SP1 reveal binding interactions with the maturation inhibitor bevirimat.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7NS4
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BU of 7ns4 by Molmil
Catalytic module of yeast Chelator-GID SR4 E3 ubiquitin ligase
分子名称: E3 ubiquitin-protein ligase RMD5, Protein FYV10, ZINC ION
著者Sherpa, D, Chrustowicz, J, Prabu, J.R, Schulman, B.A.
登録日2021-03-05
公開日2021-05-05
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
7NS3
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BU of 7ns3 by Molmil
Substrate receptor scaffolding module of yeast Chelator-GID SR4 E3 ubiquitin ligase bound to Fbp1 substrate
分子名称: BJ4_G0018240.mRNA.1.CDS.1, Fructose-bisphosphatase, Glucose-induced degradation protein 8, ...
著者Sherpa, D, Chrustowicz, J, Prabu, J.R, Schulman, B.A.
登録日2021-03-05
公開日2021-05-05
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
7NS5
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BU of 7ns5 by Molmil
Structure of yeast Fbp1 (Fructose-1,6-bisphosphatase 1)
分子名称: Fructose-1,6-bisphosphatase, MAGNESIUM ION, PHOSPHATE ION
著者Sherpa, D, Chrustowicz, J, Prabu, J.R, Schulman, B.A.
登録日2021-03-05
公開日2021-05-05
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
7Q4Y
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BU of 7q4y by Molmil
human Gid4 bound to a Gly/N-peptide
分子名称: Glucose-induced degradation protein 4 homolog
著者Sherpa, D, Chrustowicz, J, Prabu, J.R, Schulman, B.A.
登録日2021-11-02
公開日2022-03-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases.
J.Mol.Biol., 434, 2022

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件を2024-11-06に公開中

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