8QBN
Structure of the non-canonical CTLH E3 substrate receptor WDR26 bound to YPEL5
Summary for 8QBN
Entry DOI | 10.2210/pdb8qbn/pdb |
EMDB information | 18170 18171 18172 18173 18174 18175 18176 18177 18178 18316 |
Descriptor | WD repeat-containing protein 26, Protein yippee-like 5, ZINC ION (3 entities in total) |
Functional Keywords | e3 ubiquitin ligase, ctlh, gid, nmnat1, ypel5, ligase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 155136.43 |
Authors | Chrustowicz, J.,Sherpa, D.,Schulman, B.A. (deposition date: 2023-08-24, release date: 2024-05-15, Last modification date: 2024-05-29) |
Primary citation | Gottemukkala, K.V.,Chrustowicz, J.,Sherpa, D.,Sepic, S.,Vu, D.T.,Karayel, O.,Papadopoulou, E.C.,Gross, A.,Schorpp, K.,von Gronau, S.,Hadian, K.,Murray, P.J.,Mann, M.,Schulman, B.A.,Alpi, A.F. Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism. Mol.Cell, 84:1948-1963.e11, 2024 Cited by PubMed: 38759627DOI: 10.1016/j.molcel.2024.04.014 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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