7SAB
 
 | | Phencyclidine-bound GluN1a-GluN2B NMDA receptors | | 分子名称: | 1-(PHENYL-1-CYCLOHEXYL)PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Chou, T.-H, Furukawa, H. | | 登録日 | 2021-09-22 | | 公開日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
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7SAD
 | | Memantine-bound GluN1a-GluN2B NMDA receptors | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | | 著者 | Chou, T.-H, Furukawa, H. | | 登録日 | 2021-09-22 | | 公開日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | | 主引用文献 | Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
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7SAA
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7SAC
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3W52
 | | Zinc-dependent bifunctional nuclease | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Endonuclease 2, ... | | 著者 | Chou, T.L, Ko, T.P, Ko, C.Y, Shaw, J.F, Wang, A.H.J. | | 登録日 | 2013-01-18 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Mechanistic insights to catalysis by a zinc-dependent bi-functional nuclease from Arabidopsis thaliana
BIOCATAL AGRIC BIOTECHNOL, 2013
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8E94
 | | PYD-106-bound Human GluN1a-GluN2C NMDA receptor in intact conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Chou, T.-H, Furukawa, H. | | 登録日 | 2022-08-26 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-14 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
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8E92
 | | D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in intact conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | | 著者 | Chou, T.-H, Furukawa, H. | | 登録日 | 2022-08-26 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-14 | | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
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5D1R
 | | Crystal structure of Mycobacterium tuberculosis Rv1816 transcriptional regulator. | | 分子名称: | MAGNESIUM ION, NICKEL (II) ION, Rv1816 transcriptional regulator, ... | | 著者 | Chou, T.-H, Delmar, J, Su, C.-C, Yu, E. | | 登録日 | 2015-08-04 | | 公開日 | 2015-09-30 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Basis for the Regulation of the MmpL Transporters of Mycobacterium tuberculosis.
J.Biol.Chem., 290, 2015
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5D1W
 | | Crystal structure of Mycobacterium tuberculosis Rv3249c transcriptional regulator. | | 分子名称: | PALMITIC ACID, Rv3249c transcriptional regulator | | 著者 | Chou, T.-H, Delmar, J, Su, C.-C, Yu, E. | | 登録日 | 2015-08-04 | | 公開日 | 2015-09-30 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | | 主引用文献 | Structural Basis for the Regulation of the MmpL Transporters of Mycobacterium tuberculosis.
J.Biol.Chem., 290, 2015
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5D19
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5D18
 | | Crystal structure of Mycobacterium tuberculosis Rv0302, form I | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ISOPROPYL ALCOHOL, SODIUM ION, ... | | 著者 | Chou, T.-H, Delmar, J, Su, C.-C, Yu, E. | | 登録日 | 2015-08-04 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Crystal structure of the Mycobacterium tuberculosis transcriptional regulator Rv0302.
Protein Sci., 2015
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6BHP
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8E97
 | | PYD-106-bound Human GluN1a-GluN2C NMDA receptor in splayed conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | | 著者 | Chou, T.-H, Furukawa, H. | | 登録日 | 2022-08-26 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-14 | | 実験手法 | ELECTRON MICROSCOPY (4.19 Å) | | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
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8E93
 | | D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in splayed conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | | 著者 | Chou, T.-H, Furukawa, H. | | 登録日 | 2022-08-26 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-14 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
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8E99
 | | Human GluN1a-GluN2A-GluN2C triheteromeric NMDA receptor in complex with Nb-4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | | 著者 | Chou, T.-H, Furukawa, H. | | 登録日 | 2022-08-26 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-14 | | 実験手法 | ELECTRON MICROSCOPY (4.24 Å) | | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
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8E98
 | | D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in nanodisc - intact conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ... | | 著者 | Chou, T.-H, Furukawa, H. | | 登録日 | 2022-08-26 | | 公開日 | 2022-12-07 | | 最終更新日 | 2022-12-14 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.
Mol.Cell, 82, 2022
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4J4M
 | | Crystal structure of TM-1, a Trimeresurus mucrosquamatus venom metalloproteinase | | 分子名称: | ZINC ION, zinc-dependent metalloproteinase | | 著者 | Chou, T.L, Wu, C.H, Huang, K.F, Wang, A.H. | | 登録日 | 2013-02-07 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of a Trimeresurus mucrosquamatus venom metalloproteinase providing new insights into the inhibition by endogenous tripeptide inhibitors.
Toxicon, 71C, 2013
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6WHV
 | | GluN1b-GluN2B NMDA receptor in complex with SDZ 220-040 and L689,560, class 2 | | 分子名称: | (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Chou, T, Tajima, N, Furukawa, H. | | 登録日 | 2020-04-08 | | 公開日 | 2020-08-05 | | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
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6WHS
 | | GluN1b-GluN2B NMDA receptor in non-active 1 conformation at 3.95 angstrom resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | | 著者 | Chou, T, Tajima, N, Furukawa, H. | | 登録日 | 2020-04-08 | | 公開日 | 2020-08-05 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
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6WI0
 | | GluN1b-GluN2B NMDA receptor in complex with GluN1 antagonist L689,560, class 2 | | 分子名称: | (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Chou, T, Tajima, N, Furukawa, H. | | 登録日 | 2020-04-08 | | 公開日 | 2020-07-15 | | 最終更新日 | 2020-08-05 | | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
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6WHT
 | | GluN1b-GluN2B NMDA receptor in active conformation at 4.4 angstrom resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | | 著者 | Chou, T, Tajima, N, Furukawa, H. | | 登録日 | 2020-04-08 | | 公開日 | 2020-08-05 | | 実験手法 | ELECTRON MICROSCOPY (4.39 Å) | | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
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6WHX
 | | GluN1b-GluN2B NMDA receptor in complex with GluN2B antagonist SDZ 220-040, class 2 | | 分子名称: | (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ... | | 著者 | Chou, T, Tajima, N, Furukawa, H. | | 登録日 | 2020-04-08 | | 公開日 | 2020-07-15 | | 最終更新日 | 2020-08-05 | | 実験手法 | ELECTRON MICROSCOPY (4.09 Å) | | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
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6WHR
 | | GluN1b-GluN2B NMDA receptor in non-active 2 conformation at 4 angstrom resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | | 著者 | Chou, T, Tajima, N, Furukawa, H. | | 登録日 | 2020-04-08 | | 公開日 | 2020-08-05 | | 実験手法 | ELECTRON MICROSCOPY (3.99 Å) | | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
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6WI1
 | | GluN1b-GluN2B NMDA receptor in active conformation stabilized by inter-GluN1b-GluN2B subunit cross-linking | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ... | | 著者 | Chou, T, Tajima, N, Furukawa, H. | | 登録日 | 2020-04-08 | | 公開日 | 2020-07-15 | | 最終更新日 | 2020-08-05 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
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6WHU
 | | GluN1b-GluN2B NMDA receptor in complex with SDZ 220-040 and L689,560, class 1 | | 分子名称: | (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Chou, T, Tajima, N, Furukawa, H. | | 登録日 | 2020-04-08 | | 公開日 | 2020-08-05 | | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
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