4BNJ
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![BU of 4bnj by Molmil](/molmil-images/mine/4bnj) | Crystal structure of S. aureus FabI in complex with NADP and 5-methyl- 2-phenoxyphenol | 分子名称: | 5-methyl-2-phenoxyphenol, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... | 著者 | Schiebel, J, Chang, A, Bommineni, G.R, Tonge, P.J, Kisker, C. | 登録日 | 2013-05-15 | 公開日 | 2013-06-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Rational Optimization of Drug-Target Residence Time: Insights from Inhibitor Binding to the S. Aureus Fabi Enzyme-Product Complex. Biochemistry, 52, 2013
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4BNH
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![BU of 4bnh by Molmil](/molmil-images/mine/4bnh) | Crystal structure of S. aureus FabI in complex with NADP and 5-hexyl- 2-phenoxyphenol | 分子名称: | 5-hexyl-2-phenoxyphenol, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... | 著者 | Schiebel, J, Chang, A, Bommineni, G.R, Tonge, P.J, Kisker, C. | 登録日 | 2013-05-15 | 公開日 | 2013-06-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Rational Optimization of Drug-Target Residence Time: Insights from Inhibitor Binding to the S. Aureus Fabi Enzyme-Product Complex. Biochemistry, 52, 2013
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4BNL
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![BU of 4bnl by Molmil](/molmil-images/mine/4bnl) | Crystal structure of S. aureus FabI in complex with NADP and 2- phenoxy-5-(2-propenyl)phenol | 分子名称: | 2-PHENOXY-5-(2-PROPENYL)PHENOL, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... | 著者 | Schiebel, J, Chang, A, Bommineni, G.R, Tonge, P.J, Kisker, C.F. | 登録日 | 2013-05-15 | 公開日 | 2013-06-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Rational Optimization of Drug-Target Residence Time: Insights from Inhibitor Binding to the S. Aureus Fabi Enzyme-Product Complex. Biochemistry, 52, 2013
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4BNF
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![BU of 4bnf by Molmil](/molmil-images/mine/4bnf) | Crystal structure of S. aureus FabI in complex with NADP and 2- phenoxy-5-propylphenol | 分子名称: | 2-phenoxy-5-propyl-phenol, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... | 著者 | Schiebel, J, Chang, A, Bommineni, G.R, Tonge, P.J, Kisker, C. | 登録日 | 2013-05-15 | 公開日 | 2013-06-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Rational Optimization of Drug-Target Residence Time: Insights from Inhibitor Binding to the S. Aureus Fabi Enzyme-Product Complex. Biochemistry, 52, 2013
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4BNM
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![BU of 4bnm by Molmil](/molmil-images/mine/4bnm) | Crystal structure of S. aureus FabI in complex with NADP and 5-hexyl- 2-(2-methylphenoxy)phenol | 分子名称: | 5-HEXYL-2-(2-METHYLPHENOXY)PHENOL, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... | 著者 | Schiebel, J, Chang, A, Bommineni, G.R, Tonge, P.J, Kisker, C. | 登録日 | 2013-05-15 | 公開日 | 2013-06-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Rational Optimization of Drug-Target Residence Time: Insights from Inhibitor Binding to the S. Aureus Fabi Enzyme-Product Complex. Biochemistry, 52, 2013
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2ZOX
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![BU of 2zox by Molmil](/molmil-images/mine/2zox) | Crystal Structure of the Covalent Intermediate of Human Cytosolic beta-Glucosidase | 分子名称: | 4-nitrophenyl alpha-D-glucopyranoside, Cytosolic beta-glucosidase, GLYCEROL, ... | 著者 | Noguchi, J, Hayashi, Y, Baba, Y, Okino, N, Kimura, M, Ito, M, Kakuta, Y. | 登録日 | 2008-06-17 | 公開日 | 2008-09-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the covalent intermediate of human cytosolic beta-glucosidase Biochem.Biophys.Res.Commun., 374, 2008
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4WJO
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![BU of 4wjo by Molmil](/molmil-images/mine/4wjo) | Crystal Structure of SUMO1 in complex with PML | 分子名称: | Protein PML, Small ubiquitin-related modifier 1 | 著者 | Cappadocia, L, Mascle, X.H, Bourdeau, V, Tremblay-Belzile, S, Chaker-Margot, M, Lussier-Price, M, Wada, J, Sakaguchi, K, Aubry, M, Ferbeyre, G, Omichinski, J.G. | 登録日 | 2014-10-01 | 公開日 | 2014-12-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | Structural and Functional Characterization of the Phosphorylation-Dependent Interaction between PML and SUMO1. Structure, 23, 2015
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1IYF
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![BU of 1iyf by Molmil](/molmil-images/mine/1iyf) | Solution structure of ubiquitin-like domain of human parkin | 分子名称: | parkin | 著者 | Sakata, E, Yamaguchi, Y, Kurimoto, E, Kikuchi, J, Yokoyama, S, Kawahara, H, Yokosawa, H, Hattori, N, Mizuno, Y, Tanaka, K, Kato, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-08-13 | 公開日 | 2003-03-25 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain EMBO REP., 4, 2003
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1IYR
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![BU of 1iyr by Molmil](/molmil-images/mine/1iyr) | NMR Structure Ensemble Of Dff-C Domain | 分子名称: | DNA FRAGMENTATION FACTOR ALPHA SUBUNIT | 著者 | Fukushima, K, Kikuchi, J, Koshiba, S, Kigawa, T, Kuroda, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-09-05 | 公開日 | 2002-09-25 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Dff-C Domain of Dff45/Icad. A Structural Basis for the Regulation of Apoptotic DNA Fragmentation J.Mol.Biol., 321, 2002
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6YUR
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![BU of 6yur by Molmil](/molmil-images/mine/6yur) | Crystal structure of S. aureus FabI inhibited by SKTS1 | 分子名称: | 6-[4-(4-hexyl-2-oxidanyl-phenoxy)phenoxy]pyridin-2-ol, Enoyl-[acyl-carrier-protein] reductase [NADPH], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Weinrich, J.D, Eltschkner, S, Schiebel, J, Kehrein, J, Le, T.A, Davoodi, S, Merget, B, Tonge, P.J, Engels, B, Sotriffer, C.A, Kisker, C. | 登録日 | 2020-04-27 | 公開日 | 2021-03-24 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure. Acs Infect Dis., 7, 2021
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6YUU
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![BU of 6yuu by Molmil](/molmil-images/mine/6yuu) | Crystal structure of M. tuberculosis InhA inhibited by SKTS1 | 分子名称: | 6-[4-(4-hexyl-2-oxidanyl-phenoxy)phenoxy]pyridin-2-ol, CHLORIDE ION, Enoyl-[acyl-carrier-protein] reductase [NADH], ... | 著者 | Eltschkner, S, Schiebel, J, Kehrein, J, Le, T.A, Davoodi, S, Merget, B, Weinrich, J.D, Tonge, P.J, Engels, B, Sotriffer, C.A, Kisker, C. | 登録日 | 2020-04-27 | 公開日 | 2021-03-24 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure. Acs Infect Dis., 7, 2021
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5M5B
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![BU of 5m5b by Molmil](/molmil-images/mine/5m5b) | Crystal structure of Zika virus NS5 methyltransferase | 分子名称: | CHLORIDE ION, GLYCEROL, NS5 methyltransferase, ... | 著者 | Barral, K, Ortiz Lombardia, M, Coutard, B, Decroly, E, Lichiere, J. | 登録日 | 2016-10-21 | 公開日 | 2016-12-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives. J. Virol., 91, 2017
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4H9R
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![BU of 4h9r by Molmil](/molmil-images/mine/4h9r) | Complex structure 5 of DAXX(E225A)/H3.3(sub5,G90A)/H4 | 分子名称: | Death domain-associated protein 6, Histone H3.3, Histone H4, ... | 著者 | Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J. | 登録日 | 2012-09-24 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | 主引用文献 | DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out To be Published
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4H9O
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![BU of 4h9o by Molmil](/molmil-images/mine/4h9o) | Complex structure 2 of DAXX/H3.3(sub5,G90M)/H4 | 分子名称: | Death domain-associated protein 6, Histone H3.3, Histone H4, ... | 著者 | Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J. | 登録日 | 2012-09-24 | 公開日 | 2012-10-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.053 Å) | 主引用文献 | DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out To be Published
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4H9Q
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![BU of 4h9q by Molmil](/molmil-images/mine/4h9q) | Complex structure 4 of DAXX(E225A)/H3.3(sub5)/H4 | 分子名称: | Death domain-associated protein 6, Histone H3.3, Histone H4, ... | 著者 | Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J. | 登録日 | 2012-09-24 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out To be Published
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6T94
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![BU of 6t94 by Molmil](/molmil-images/mine/6t94) | NAD+-dependent fungal formate dehydrogenase from Chaetomium thermophilum: A complex of N120C mutant protein with the reduced form of the cofactor NADH. | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Isupov, M.N, Yelmazer, B, De Rose, S.A, Littlechild, J.A. | 登録日 | 2019-10-25 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Structural insights into the NAD + -dependent formate dehydrogenase mechanism revealed from the NADH complex and the formate NAD + ternary complex of the Chaetomium thermophilum enzyme. J.Struct.Biol., 212, 2020
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6T8Y
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![BU of 6t8y by Molmil](/molmil-images/mine/6t8y) | NAD+-dependent fungal formate dehydrogenase from Chaetomium thermophilum: A complex with the reduced form of the cofactor NADH and the substrate formate at a secondary site. | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Isupov, M.N, Yelmazer, B, De Rose, S.A, Littlechild, J.A. | 登録日 | 2019-10-25 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Structural insights into the NAD + -dependent formate dehydrogenase mechanism revealed from the NADH complex and the formate NAD + ternary complex of the Chaetomium thermophilum enzyme. J.Struct.Biol., 212, 2020
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6GSD
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![BU of 6gsd by Molmil](/molmil-images/mine/6gsd) | Plantago Major multifunctional oxidoreductase in complex with progesterone and NADP+ | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROGESTERONE, Progesterone 5-beta-reductase | 著者 | Fellows, R, Silva, C, Russo, C.M, Lee, S.G, Jez, J.M, Chisholm, J.D, Zubieta, C, Nanao, M. | 登録日 | 2018-06-14 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A multisubstrate reductase from Plantago major: structure-function in the short chain reductase superfamily. Sci Rep, 8, 2018
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4UBQ
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![BU of 4ubq by Molmil](/molmil-images/mine/4ubq) | Crystal Structure of IMP-2 Metallo-beta-Lactamase from Acinetobacter spp. | 分子名称: | ACETATE ION, Beta-lactamase, ZINC ION | 著者 | Yamaguchi, Y, Matsueda, S, Matsunaga, K, Takashio, N, Toma-Fukai, S, Yamagata, Y, Shibata, N, Wachino, J, Shibayama, K, Arakawa, Y, Kurosaki, H. | 登録日 | 2014-08-13 | 公開日 | 2014-12-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of IMP-2 metallo-beta-lactamase from Acinetobacter spp.: comparison of active-site loop structures between IMP-1 and IMP-2. Biol.Pharm.Bull., 38, 2015
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6ZGA
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![BU of 6zga by Molmil](/molmil-images/mine/6zga) | COPII on membranes, inner coat | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, PRO-PRO-PRO, ... | 著者 | Zanetti, G, Hutchings, J, Cheung, A.C.M. | 登録日 | 2020-06-18 | 公開日 | 2021-02-17 | 最終更新日 | 2021-04-14 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network. Nat Commun, 12, 2021
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6ZG6
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![BU of 6zg6 by Molmil](/molmil-images/mine/6zg6) | COPII on membranes, outer coat vertex | 分子名称: | Protein transport protein SEC13, Protein transport protein SEC31 | 著者 | Zanetti, G, Hutchings, J. | 登録日 | 2020-06-18 | 公開日 | 2021-02-17 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (12 Å) | 主引用文献 | Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network. Nat Commun, 12, 2021
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4V5M
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![BU of 4v5m by Molmil](/molmil-images/mine/4v5m) | tRNA tranlocation on the 70S ribosome: the pre-translocational translocation intermediate TI(PRE) | 分子名称: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Ratje, A.H, Loerke, J, Mikolajka, A, Bruenner, M, Hildebrand, P.W, Starosta, A.L, Doenhoefer, A, Connell, S.R, Fucini, P, Mielke, T, Whitford, P.C, Onuchic, J.N, Yu, Y, Sanbonmatsu, K.Y, Hartmann, R.K, Penczek, P.A, Wilson, D.N, Spahn, C.M.T. | 登録日 | 2010-10-01 | 公開日 | 2014-07-09 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | 主引用文献 | Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites. Nature, 468, 2010
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4UHH
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![BU of 4uhh by Molmil](/molmil-images/mine/4uhh) | Structural studies of a thermophilic esterase from Thermogutta terrifontis (cacodylate complex) | 分子名称: | CACODYLIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Sayer, C, Isupov, M.N, Bonch-Osmolovskaya, E, Littlechild, J.A. | 登録日 | 2015-03-24 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | 主引用文献 | Structural Studies of a Thermophilic Esterase from a New Planctomycetes Species, Thermogutta Terrifontis. FEBS J., 282, 2015
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4UHE
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![BU of 4uhe by Molmil](/molmil-images/mine/4uhe) | Structural studies of a thermophilic esterase from Thermogutta terrifontis (malate bound) | 分子名称: | CHLORIDE ION, D-MALATE, ESTERASE, ... | 著者 | Sayer, C, Isupov, M.N, Bonch-Osmolovskaya, E, Littlechild, J.A. | 登録日 | 2015-03-24 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | 主引用文献 | Structural Studies of a Thermophilic Esterase from a New Planctomycetes Species, Thermogutta Terrifontis. FEBS J., 282, 2015
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4UHF
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![BU of 4uhf by Molmil](/molmil-images/mine/4uhf) | Structural studies of a thermophilic esterase from Thermogutta terrifontis (L37A mutant with butyrate bound) | 分子名称: | CACODYLIC ACID, ESTERASE, TRIETHYLENE GLYCOL, ... | 著者 | Sayer, C, Isupov, M.N, Bonch-Osmolovskaya, E, Littlechild, J.A. | 登録日 | 2015-03-24 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | Structural Studies of a Thermophilic Esterase from a New Planctomycetes Species, Thermogutta Terrifontis. FEBS J., 282, 2015
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