NAD+-dependent fungal formate dehydrogenase from Chaetomium thermophilum: A complex of N120C mutant protein with the reduced form of the cofactor NADH.

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Summary for 6T94

DescriptorFormate dehydrogenase, DI(HYDROXYETHYL)ETHER, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... (5 entities in total)
Functional Keywordsnadh, cytosolic protein
Biological sourceChaetomium thermophilum
Total number of polymer chains4
Total molecular weight186210.67
Isupov, M.N.,Yelmazer, B.,De Rose, S.A.,Littlechild, J.A. (deposition date: 2019-10-25, release date: 2020-11-18)
Primary citation
Yelmazer, B.,Isupov, M.N.,De Rose, S.A.,Bulut, H.,Benninghoff, J.C.,Binay, B.,Littlechild, J.A.
Structural insights into the reduced cofactor structure and the formate ternary complex of the fungal NAD+-dependent formate dehydrogenase from Chaetomium thermophilum
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.22550 1.1% 7.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-12-02