6T8Y

NAD+-dependent fungal formate dehydrogenase from Chaetomium thermophilum: A complex with the reduced form of the cofactor NADH and the substrate formate at a secondary site.

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Summary for 6T8Y

DescriptorFormate dehydrogenase, DI(HYDROXYETHYL)ETHER, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... (6 entities in total)
Functional Keywordsnad+, cytosolic protein
Biological sourceChaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
Total number of polymer chains4
Total molecular weight186526.7
Authors
Isupov, M.N.,Yelmazer, B.,De Rose, S.A.,Littlechild, J.A. (deposition date: 2019-10-25, release date: 2020-11-18)
Primary citation
Yelmazer, B.,Isupov, M.N.,De Rose, S.A.,Bulut, H.,Benninghoff, J.C.,Binay, B.,Littlechild, J.A.
Structural insights into the reduced cofactor structure and the formate ternary complex of the fungal NAD+-dependent formate dehydrogenase from Chaetomium thermophilum
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.26 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.19860 0.7% 8.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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171588
PDB entries from 2020-11-25