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PDB: 437 件
6LBG
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BU of 6lbg by Molmil
Structure of OR51B2 bound FEM1C
分子名称: Protein fem-1 homolog C,Peptide from Olfactory receptor 51B2, SULFATE ION
著者Chen, X, Liao, S, Xu, C.
登録日2019-11-14
公開日2020-10-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
6LE6
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BU of 6le6 by Molmil
Structure of LNLPTQGRAR bound FEM1C
分子名称: Protein fem-1 homolog C,10-mer peptide, SULFATE ION
著者Chen, X, Liao, S, Xu, C.
登録日2019-11-24
公開日2020-10-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
6LBF
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BU of 6lbf by Molmil
Crystal structure of FEM1B
分子名称: Protein fem-1 homolog B, SULFATE ION
著者Chen, X, Liao, S, Xu, C.
登録日2019-11-14
公開日2020-10-21
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.252 Å)
主引用文献Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
6LDP
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BU of 6ldp by Molmil
Structure of CDK5R1-bound FEM1C
分子名称: Protein fem-1 homolog C,Peptide from Cyclin-dependent kinase 5 activator 1, SULFATE ION
著者Chen, X, Liao, S, Xu, C.
登録日2019-11-22
公開日2020-10-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
6LEN
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BU of 6len by Molmil
Structure of NS11 bound FEM1C
分子名称: Protein fem-1 homolog C,NS11 peptide
著者Chen, x, Liao, S, Xu, C.
登録日2019-11-25
公開日2020-10-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.383 Å)
主引用文献Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
6LF0
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BU of 6lf0 by Molmil
Structure of FEM1C
分子名称: Protein fem-1 homolog C, SULFATE ION
著者Chen, X, Liao, S, Xu, C.
登録日2019-11-27
公開日2020-10-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
6LBN
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BU of 6lbn by Molmil
Structure of SIL1-bound FEM1C
分子名称: Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1
著者Chen, X, Liao, S, Xu, C.
登録日2019-11-14
公開日2020-10-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.899 Å)
主引用文献Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
6LEY
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BU of 6ley by Molmil
Structure of Sil1G bound FEM1C
分子名称: Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1
著者Chen, X, Liao, S, Xu, C.
登録日2019-11-27
公開日2020-10-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
6KUZ
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BU of 6kuz by Molmil
E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSL01
分子名称: 3-(1,3-benzothiazol-2-yl)-2-[[4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]methoxy]-5-methyl-benzaldehyde, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Chen, X, Hu, Y.L, Li, X.K, Guo, Y, Li, J.
登録日2019-09-03
公開日2020-07-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献First-generation species-selective chemical probes for fluorescence imaging of human senescence-associated beta-galactosidase.
Chem Sci, 11, 2020
6JPE
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BU of 6jpe by Molmil
Crystal structure of FGFR4 kinase domain with irreversible inhibitor 1
分子名称: Fibroblast growth factor receptor 4, N-[2-[[6-[2-[[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]amino]pyridin-3-yl]pyrimidin-4-yl]amino]-3-methyl-phenyl]prop-2-enamide, SULFATE ION
著者Chen, X, Dai, S, Zhou, Z, Chen, Y.
登録日2019-03-26
公開日2020-05-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Development of a Potent and Specific FGFR4 Inhibitor for the Treatment of Hepatocellular Carcinoma.
J.Med.Chem., 63, 2020
7DWS
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BU of 7dws by Molmil
The structure of T4 Lysozyme I3C/C54T/R125C/E128C complex with Zinc ions
分子名称: Endolysin, ZINC ION
著者Chen, X, Chen, S.
登録日2021-01-17
公開日2021-06-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Rationally designed protein cross-linked hydrogel for bone regeneration via synergistic release of magnesium and zinc ions.
Biomaterials, 274, 2021
5W77
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BU of 5w77 by Molmil
Solution structure of the MYC G-quadruplex bound to small molecule DC-34
分子名称: 4-[(azepan-1-yl)methyl]-5-hydroxy-2-methyl-N-[4-(trifluoromethyl)phenyl]-1-benzofuran-3-carboxamide, DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3'), POTASSIUM ION
著者Chen, X, Walters, K.J.
登録日2017-06-19
公開日2018-10-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex.
Nat Commun, 9, 2018
5XFS
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BU of 5xfs by Molmil
Crystal structure of PE8-PPE15 in complex with EspG5 from M. tuberculosis
分子名称: ESX-5 secretion-associated protein EspG5, PE family protein PE8, PPE family protein PPE15
著者Chen, X, Au, S.W.N.
登録日2017-04-11
公開日2017-08-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of the PE-PPE protein interaction in Mycobacterium tuberculosis.
J. Biol. Chem., 292, 2017
7ENA
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BU of 7ena by Molmil
TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED)
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y.
登録日2021-04-16
公開日2021-05-26
最終更新日2021-06-16
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
7ENC
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BU of 7enc by Molmil
TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED)
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y.
登録日2021-04-16
公開日2021-05-26
最終更新日2021-06-16
実験手法ELECTRON MICROSCOPY (4.13 Å)
主引用文献Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
5YQG
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BU of 5yqg by Molmil
The structure of 14-3-3 and pNumb peptide
分子名称: 14-3-3 protein eta, Peptide from Protein numb homolog
著者Chen, X, Liu, Z, Wen, W.
登録日2017-11-06
公開日2018-02-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural determinants controlling 14-3-3 recruitment to the endocytic adaptor Numb and dissociation of the Numb/alpha-adaptin complex.
J. Biol. Chem., 293, 2018
5ZCS
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BU of 5zcs by Molmil
4.9 Angstrom Cryo-EM structure of human mTOR complex 2
分子名称: Rapamycin-insensitive companion of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex 2 subunit MAPKAP1, ...
著者Chen, X, Liu, M, Tian, Y, Wang, H, Wang, J, Xu, Y.
登録日2018-02-20
公開日2018-03-21
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Cryo-EM structure of human mTOR complex 2.
Cell Res., 28, 2018
6LYN
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BU of 6lyn by Molmil
CD146 D4-D5/AA98 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AA98 Fab heavy chain, ...
著者Chen, X, Yan, X.
登録日2020-02-14
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.776 Å)
主引用文献Structure basis for AA98 inhibition on the activation of endothelial cells mediated by CD146.
Iscience, 24, 2021
6K9C
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BU of 6k9c by Molmil
The apo structure of NrS-1 C terminal region (305-718)
分子名称: MERCURY (II) ION, Primase, SULFATE ION
著者Chen, X, Gan, J.
登録日2019-06-14
公開日2020-04-08
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.406 Å)
主引用文献Structural studies reveal a ring-shaped architecture of deep-sea vent phage NrS-1 polymerase.
Nucleic Acids Res., 48, 2020
6K9E
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BU of 6k9e by Molmil
The A form apo structure of NrS-1 C terminal region-CTR(305-718)
分子名称: PHOSPHATE ION, Primase
著者Chen, X, Gan, J.
登録日2019-06-14
公開日2020-06-17
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural studies reveal a ring-shaped architecture of deep-sea vent phage NrS-1 polymerase.
Nucleic Acids Res., 48, 2020
6LRB
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BU of 6lrb by Molmil
The A form apo structure of NrS-1 C terminal region-CTR
分子名称: MAGNESIUM ION, Primase
著者Chen, X, Gan, J.
登録日2020-01-15
公開日2020-04-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural studies reveal a ring-shaped architecture of deep-sea vent phage NrS-1 polymerase.
Nucleic Acids Res., 48, 2020
7XYO
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BU of 7xyo by Molmil
Crystal Structure of a M61 aminopeptidase family member from Myxococcus fulvus
分子名称: Aminopeptidase M61, HEXAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ...
著者Chen, X, Wang, X, Huo, L, Wu, D.
登録日2022-06-02
公開日2023-06-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery and Characterization of a Myxobacterial Lanthipeptide with Unique Biosynthetic Features and Anti-inflammatory Activity.
J.Am.Chem.Soc., 145, 2023
7CNG
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BU of 7cng by Molmil
Structure of CDK5R1 bound FEM1B
分子名称: Protein fem-1 homolog B,Peptide from Cyclin-dependent kinase 5 activator 1, SULFATE ION
著者Chen, X, Liao, S, Xu, C.
登録日2020-07-31
公開日2020-10-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
8GRD
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BU of 8grd by Molmil
Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ADP and Mg
分子名称: ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ...
著者Chen, X, Sun, P, Ding, J.
登録日2022-09-01
公開日2022-11-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.699 Å)
主引用文献Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
8HHX
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BU of 8hhx by Molmil
SARS-CoV-2 Delta Spike in complex with FP-12A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FP-12A Fab heavy chain, ...
著者Chen, X, Wu, Y.-M.
登録日2022-11-17
公開日2023-02-01
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2.
Nat Commun, 14, 2023

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