2B3Z
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5GUT
| The crystal structure of mouse DNMT1 (731-1602) mutant - N1248A | Descriptor: | DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | Authors: | Chen, S.J, Ye, F. | Deposit date: | 2016-08-31 | Release date: | 2017-09-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1. ACS Chem. Biol., 13, 2018
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2ZJO
| Crystal structure of hepatitis C virus NS3 helicase with a novel inhibitor | Descriptor: | Genome polyprotein, N-[4-(BIS{4-[(3-SULFOPHENYL)AMINO]PHENYL}METHYLENE)CYCLOHEXA-2,5-DIEN-1-YLIDENE]-4-SULFOBENZENAMINIUM | Authors: | Liaw, S.H, Chen, S.J, Hu, C.Y, Chi, W.K, Chu, I.D, Hwang, L.H, Chern, J.W, Chen, D.S. | Deposit date: | 2008-03-07 | Release date: | 2009-03-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-Based Discovery of Triphenylmethane Derivatives as Novel Inhibitors of Hepatitis C Virus Helicase To be Published
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4LZX
| Complex of IQCG and Ca2+-free CaM | Descriptor: | Calmodulin, IQ domain-containing protein G, SULFATE ION | Authors: | Liang, W.X, Chen, L.T, Chen, Z, Chen, S.J, Chen, S. | Deposit date: | 2013-08-01 | Release date: | 2014-05-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish Nat Commun, 5, 2014
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4M1L
| Complex of IQCG and Ca2+-bound CaM | Descriptor: | CALCIUM ION, Calmodulin, IQ domain-containing protein G, ... | Authors: | Liang, W.X, Chen, L.T, Chen, Z, Chen, S.J, Chen, S. | Deposit date: | 2013-08-03 | Release date: | 2014-05-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish Nat Commun, 5, 2014
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6IMQ
| Crystal structure of PML B1-box multimers | Descriptor: | CHLORIDE ION, Protein PML, ZINC ION | Authors: | Li, Y, Ma, X, Chen, Z, Wu, H, Wang, P, Wu, W, Cheng, N, Zeng, L, Zhang, H, Cai, X, Chen, S.J, Chen, Z, Meng, G. | Deposit date: | 2018-10-23 | Release date: | 2019-07-31 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis. Nat Commun, 10, 2019
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2D5N
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7X1N
| Crystal structure of MEF2D-MRE complex | Descriptor: | DNA (5'-D(P*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*G)-3'), DNA (5'-D(P*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*T)-3'), Myocyte enhancer factor 2D/deleted in azoospermia associated protein 1 fusion protein | Authors: | Zhang, H, Zhang, M, Wang, Q.Q, Chen, Z, Chen, S.J, Meng, G. | Deposit date: | 2022-02-24 | Release date: | 2022-05-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.315 Å) | Cite: | Functional, structural, and molecular characterizations of the leukemogenic driver MEF2D-HNRNPUL1 fusion. Blood, 140, 2022
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8HFR
| NPC-trapped pre-60S particle | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Li, Z.Q, Chen, S.J, Sui, S.F. | Deposit date: | 2022-11-12 | Release date: | 2023-04-12 | Last modified: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | Nuclear export of pre-60S particles through the nuclear pore complex. Nature, 618, 2023
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8HBN
| Structure of the Mex67-Mtr2-1 heterodimer | Descriptor: | mRNA export factor MEX67, mRNA transport regulator MTR2 | Authors: | Li, Z.Q, Chen, S.J, Sui, S.F. | Deposit date: | 2022-10-29 | Release date: | 2023-04-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | Nuclear export of pre-60S particles through the nuclear pore complex. Nature, 618, 2023
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5GUV
| The crystal structure of mouse DNMT1 (731-1602) mutant - R1279D | Descriptor: | DNA (cytosine-5)-methyltransferase 1, ZINC ION | Authors: | Ye, F, Chen, S.J. | Deposit date: | 2016-08-31 | Release date: | 2017-08-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.078 Å) | Cite: | Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1. ACS Chem. Biol., 13, 2018
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