7Y6E
 
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7Y54
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7Y8S
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7Y6O
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7Y8I
 | | Crystal structure of sDscam FNIII3 domain, isoform alpha7 | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Dscam, ... | | Authors: | Chen, Q, Yu, Y, Cheng, J. | | Deposit date: | 2022-06-24 | | Release date: | 2023-05-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
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7Y9A
 | | Crystal structure of sDscam Ig1-2 domains, isoform beta2v6 | | Descriptor: | Down Syndrome Cell Adhesion Molecules, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-3)][beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Chen, Q, Yu, Y, Cheng, J. | | Deposit date: | 2022-06-24 | | Release date: | 2023-05-24 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
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7Y95
 | | Crystal structure of sDscam Ig1 domain, isoform beta6v2 | | Descriptor: | Dscam, GLYCEROL, SODIUM ION | | Authors: | Chen, Q, Yu, Y, Cheng, J. | | Deposit date: | 2022-06-24 | | Release date: | 2023-05-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
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7Y8H
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3LAF
 | | Structure of DCC, a netrin-1 receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Deleted in Colorectal Cancer, SULFATE ION, ... | | Authors: | Chen, Q, Liu, J.-H, Wang, J.-H. | | Deposit date: | 2010-01-06 | | Release date: | 2011-03-02 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | N-terminal horseshoe conformation of DCC is functionally required for axon guidance and might be shared by other neural receptors.
J.Cell.Sci., 126, 2013
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6LJM
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6KNZ
 | | Crystal structure of T2R-TTL-KXO1 complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[5-[4-(2-morpholin-4-ylethoxy)phenyl]pyridin-2-yl]-~{N}-(phenylmethyl)ethanamide, CALCIUM ION, ... | | Authors: | Chen, Q, Yu, Y. | | Deposit date: | 2019-08-07 | | Release date: | 2019-10-23 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.475 Å) | | Cite: | Reversible binding of the anticancer drug KXO1 (tirbanibulin) to the colchicine-binding site of beta-tubulin explains KXO1's low clinical toxicity.
J.Biol.Chem., 294, 2019
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7Y4X
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3Q5Y
 | | V beta/V beta homodimerization-based pre-TCR model suggested by TCR beta crystal structures | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Chen, Q, Zhang, H, Wang, J.-H. | | Deposit date: | 2010-12-30 | | Release date: | 2011-03-09 | | Last modified: | 2014-10-15 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A conserved hydrophobic patch on Vbeta domains revealed by TCRbeta chain crystal structures: implications for pre-TCR dimerization
Front Immunol, 2, 2011
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7EPW
 | | Crystal structure of monooxygenase Tet(X4) with tigecycline | | Descriptor: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase, TIGECYCLINE | | Authors: | Cheng, Q, Chen, S. | | Deposit date: | 2021-04-28 | | Release date: | 2021-11-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Structural and mechanistic basis of the high catalytic activity of monooxygenase Tet(X4) on tigecycline.
Bmc Biol., 19, 2021
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7EPV
 | | Crystal structure of tigecycline degrading monooxygenase Tet(X4) | | Descriptor: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase, GLYCEROL | | Authors: | Cheng, Q, Chen, S. | | Deposit date: | 2021-04-27 | | Release date: | 2021-11-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Structural and mechanistic basis of the high catalytic activity of monooxygenase Tet(X4) on tigecycline.
Bmc Biol., 19, 2021
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3Q5T
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6LDU
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6LE7
 | | Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 2 | | Descriptor: | (4R)-3-(2-hydroxyphenyl)-4-(3-methoxy-4-propoxy-phenyl)-5-(pyridin-3-ylmethyl)-1,4-dihydropyrrolo[3,4-c]pyrazol-6-one, Probable endochitinase | | Authors: | Chen, Q, Yang, Q, Zhou, Y. | | Deposit date: | 2019-11-24 | | Release date: | 2021-05-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.85753441 Å) | | Cite: | Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 2
To Be Published
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6LE8
 | | Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 1 | | Descriptor: | (4R)-4-(4-ethoxyphenyl)-3-(2-hydroxyphenyl)-5-(pyridin-3-ylmethyl)-1,4-dihydropyrrolo[3,4-c]pyrazol-6-one, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... | | Authors: | Chen, Q, Yang, Q, Zhou, Y. | | Deposit date: | 2019-11-24 | | Release date: | 2021-05-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.39909327 Å) | | Cite: | Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 1
To Be Published
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7MTB
 | | Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab6 | | Descriptor: | Fab6 heavy chain, Fab6 light chain, RETINAL, ... | | Authors: | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | | Deposit date: | 2021-05-13 | | Release date: | 2021-07-07 | | Last modified: | 2021-08-25 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
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7MT8
 | | Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin | | Descriptor: | RETINAL, Rhodopsin, Rhodopsin kinase GRK1, ... | | Authors: | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | | Deposit date: | 2021-05-13 | | Release date: | 2021-07-07 | | Last modified: | 2021-08-25 | | Method: | ELECTRON MICROSCOPY (5.8 Å) | | Cite: | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
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7MTA
 | | Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab1 | | Descriptor: | Fab1 Heavy chain, Fab1 Light chain, RETINAL, ... | | Authors: | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | | Deposit date: | 2021-05-13 | | Release date: | 2021-07-07 | | Last modified: | 2021-08-25 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
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7MT9
 | | Rhodopsin kinase (GRK1) in complex with rhodopsin | | Descriptor: | RETINAL, Rhodopsin, Rhodopsin kinase GRK1, ... | | Authors: | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | | Deposit date: | 2021-05-13 | | Release date: | 2021-07-07 | | Last modified: | 2021-08-25 | | Method: | ELECTRON MICROSCOPY (7 Å) | | Cite: | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
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6CTE
 | | 77Se-NMR probes the protein environment of selenomethionine | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... | | Authors: | Chen, Q, Rozovsky, S. | | Deposit date: | 2018-03-22 | | Release date: | 2019-07-10 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | 77Se NMR Probes the Protein Environment of Selenomethionine.
J.Phys.Chem.B, 124, 2020
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6CPZ
 | | Selenomethionine mutant (I6Sem) of protein GB1 examined by X-ray diffraction | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Immunoglobulin G-binding protein G, ... | | Authors: | Chen, Q, Rozovsky, S. | | Deposit date: | 2018-03-14 | | Release date: | 2019-07-10 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.12 Å) | | Cite: | 77Se NMR Probes the Protein Environment of Selenomethionine.
J.Phys.Chem.B, 124, 2020
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