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PDB: 621 results

8JTW
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BU of 8jtw by Molmil
hOCT1 in complex with nb5660 in inward facing partially open 1 conformation
Descriptor: Solute carrier family 22 member 1, nanobody 56
Authors:Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X.
Deposit date:2023-06-22
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
8JTZ
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BU of 8jtz by Molmil
hOCT1 in complex with spironolactone in outward facing partially occluded conformation
Descriptor: SPIRONOLACTONE, Solute carrier family 22 member 1
Authors:Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X.
Deposit date:2023-06-22
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
4DGX
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BU of 4dgx by Molmil
LEOPARD Syndrome-Associated SHP2/Y279C mutant
Descriptor: Tyrosine-protein phosphatase non-receptor type 11
Authors:Yu, Z.H, Xu, J, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L.N, Liu, S.J, Zhang, Z.Y.
Deposit date:2012-01-27
Release date:2013-03-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Mechanistic Insights into LEOPARD Syndrome-Associated SHP2 Mutations.
J.Biol.Chem., 288, 2013
4DGP
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BU of 4dgp by Molmil
The wild-type Src homology 2 (SH2)-domain containing protein tyrosine phosphatase-2 (SHP2)
Descriptor: Tyrosine-protein phosphatase non-receptor type 11
Authors:Yu, Z.H, Xu, J, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L.N, Liu, S.J, Zhang, Z.Y.
Deposit date:2012-01-26
Release date:2013-03-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Mechanistic Insights into LEOPARD Syndrome-Associated SHP2 Mutations.
J.Biol.Chem., 288, 2013
3FKU
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BU of 3fku by Molmil
Crystal structure of influenza hemagglutinin (H5) in complex with a broadly neutralizing antibody F10
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Neutralizing antibody F10, ...
Authors:Hwang, W.C, Santelli, E, Stec, B, Wei, G, Cadwell, G, Bankston, L.A, Sui, J, Perez, S, Aird, D, Chen, L.M, Ali, M, Murakami, A, Yammanuru, A, Han, T, Cox, N, Donis, R.O, Liddington, R.C, Marasco, W.A.
Deposit date:2008-12-17
Release date:2009-02-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses.
Nat.Struct.Mol.Biol., 16, 2009
3NPH
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BU of 3nph by Molmil
Crystal structure of the pfam00427 domain from Synechocystis sp. PCC 6803
Descriptor: Phycobilisome 32.1 kDa linker polypeptide, phycocyanin-associated, rod 2
Authors:Gao, X, Chen, L, Wu, J.-W, Zhang, Y.-Z.
Deposit date:2010-06-28
Release date:2011-06-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Crystal structure of the N-terminal domain of linker L(R) and the assembly of cyanobacterial phycobilisome rods
Mol.Microbiol., 82, 2011
6NEB
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BU of 6neb by Molmil
MYC Promoter G-Quadruplex with 1:6:1 loop length
Descriptor: DNA (27-MER)
Authors:Dickerhoff, J, Onel, B, Chen, L, Chen, Y, Yang, D.
Deposit date:2018-12-17
Release date:2019-02-13
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution Structure of a MYC Promoter G-Quadruplex with 1:6:1 Loop Length.
Acs Omega, 4, 2019
3R2A
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BU of 3r2a by Molmil
Crystal structure of RXRalpha ligand-binding domain complexed with corepressor SMRT2 and antagonist rhein
Descriptor: 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid, Nuclear receptor corepressor 2, Retinoic acid receptor RXR-alpha
Authors:Zhang, H, Chen, L, Chen, J, Jiang, H, Shen, X.
Deposit date:2011-03-14
Release date:2011-05-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for retinoic x receptor repression on the tetramer.
J.Biol.Chem., 286, 2011
3QRF
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BU of 3qrf by Molmil
Structure of a domain-swapped FOXP3 dimer
Descriptor: Forkhead box protein P3, MAGNESIUM ION, Nuclear factor of activated T-cells, ...
Authors:Bandukwala, H.S, Wu, Y, Feurer, M, Chen, Y, Barbosa, B, Ghosh, S, Stroud, J.C, Benoist, C, Mathis, D, Rao, A, Chen, L.
Deposit date:2011-02-17
Release date:2011-04-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells.
Immunity, 34, 2011
1NLM
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BU of 1nlm by Molmil
CRYSTAL STRUCTURE OF MURG:GLCNAC COMPLEX
Descriptor: GLYCEROL, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
Authors:Hu, Y, Chen, L, Ha, S, Gross, B, Falcone, B, Walker, D, Mokhtarzadeh, M, Walker, S.
Deposit date:2003-01-07
Release date:2003-02-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases
Proc.Natl.Acad.Sci.USA, 100, 2003
3G7N
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BU of 3g7n by Molmil
Crystal Structure of a Triacylglycerol Lipase from Penicillium Expansum at 1.3
Descriptor: DI(HYDROXYETHYL)ETHER, Lipase, PENTAETHYLENE GLYCOL, ...
Authors:Bian, C.B, Yuan, C, Chen, L.Q, Edward, J.M, Lin, L, Jiang, L.G, Huang, Z.X, Huang, M.D.
Deposit date:2009-02-10
Release date:2010-02-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of a triacylglycerol lipase from Penicillium expansum at 1.3 A determined by sulfur SAD
Proteins, 78, 2010
2PK8
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BU of 2pk8 by Molmil
Crystal structure of an uncharacterized protein PF0899 from Pyrococcus furiosus
Descriptor: GOLD (I) CYANIDE ION, Uncharacterized protein PF0899
Authors:Liu, Z.J, Tempel, W, Chen, L, Shah, A, Lee, D, Clancy-Kelley, L.L, Dillard, B.D, Rose, J.P, Sugar, F.J, Jenny Jr, F.E, Lee, H.S, Izumi, M, Shah, C, Poole III, F.L, Adams, M.W.W, Richardson, J.S, Richardson, D.C, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2007-04-17
Release date:2007-05-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of the hypothetical protein PF0899 from Pyrococcus furiosus at 1.85 A resolution.
Acta Crystallogr.,Sect.F, 63, 2007
2EB2
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BU of 2eb2 by Molmil
Crystal structure of mutated EGFR kinase domain (G719S)
Descriptor: Epidermal growth factor receptor
Authors:Yoshikawa, S, Kukimoto-Niino, M, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Senba, K, Yamamoto, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-06
Release date:2008-02-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor
Oncogene, 2012
2DYY
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BU of 2dyy by Molmil
Crystal structure of putative translation initiation inhibitor PH0854 from Pyrococcus horikoshii
Descriptor: UPF0076 protein PH0854
Authors:Ihsanawati, Kishishita, S, Murayama, K, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Bessho, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-09-19
Release date:2007-03-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of putative translation initiation inhibitor PH0854 from Pyrococcus horikoshii
To be Published
1AJB
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BU of 1ajb by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE D153G MUTANT OF E. COLI ALKALINE PHOSPHATASE: A MUTANT WITH WEAKER MAGNESIUM BINDING AND INCREASED CATALYTIC ACTIVITY
Descriptor: ALKALINE PHOSPHATASE, MAGNESIUM ION, SULFATE ION, ...
Authors:Dealwis, C.G, Chen, L, Abad-Zapatero, C.
Deposit date:1995-08-19
Release date:1995-11-14
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:3-D structure of the D153G mutant of Escherichia coli alkaline phosphatase: an enzyme with weaker magnesium binding and increased catalytic activity.
Protein Eng., 8, 1995
1RYQ
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BU of 1ryq by Molmil
Putative DNA-directed RNA polymerase, subunit e'' from Pyrococcus Furiosus Pfu-263306-001
Descriptor: DNA-directed RNA polymerase, subunit e'', ZINC ION
Authors:Liu, Z.-J, Chen, L, Tempel, W, Shah, A, Arendall III, W.B, Rose, J.P, Brereton, P.S, Izumi, M, Jenney Jr, F.E, Lee, H.S, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Richardson, D.C, Richardson, J.S, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2003-12-22
Release date:2004-08-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Parameter-space screening: a powerful tool for high-throughput crystal structure determination.
Acta Crystallogr.,Sect.D, 61, 2005
1D8F
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BU of 1d8f by Molmil
CRYSTAL STRUCTURE OF MMP3 COMPLEXED WITH A PIPERAZINE BASED INHIBITOR.
Descriptor: CALCIUM ION, N-HYDROXY-1-(4-METHOXYPHENYL)SULFONYL-4-BENZYLOXYCARBONYL-PIPERAZINE-2-CARBOXAMIDE, STROMELYSIN-1 PRECURSOR, ...
Authors:Cheng, M.Y, De, B, Pikul, S, Almstead, N.G, Natchus, M.G, Anastasio, M.V, McPhail, S.J, Snider, C.E, Taiwo, Y.O, Chen, L.Y.
Deposit date:1999-10-22
Release date:2000-10-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Design and synthesis of piperazine-based matrix metalloproteinase inhibitors.
J.Med.Chem., 43, 2000
3CQ2
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BU of 3cq2 by Molmil
Structure of the DTDP-4-Keto-L-Rhamnose Reductase related protein (other form) from Thermus Thermophilus HB8
Descriptor: Putative uncharacterized protein TTHB138
Authors:Jeyakanthan, J, Kanaujia, S.P, Sekar, K, Satoh, S, Kitamura, Y, Ebihara, A, Chen, L, Liu, Z.J, Wang, B.C, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2008-04-02
Release date:2009-04-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the DTDP-4-Keto-L-Rhamnose Reductase related protein from Thermus Thermophilus HB8
To be Published
8B9P
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BU of 8b9p by Molmil
ACE2 in complex with bicyclic peptide inhibitor
Descriptor: 1-[3,5-bis(3-bromanylpropanoyl)-1,3,5-triazinan-1-yl]-3-bromanyl-propan-1-one, ALA-CYS-GLY-ARG-GLN-PHE-CYS-HIS-THR-LEU-MET-PRO-ARG-HIS-LEU-CYS-ALA-NH2, Processed angiotensin-converting enzyme 2
Authors:Brear, P, Lulla, A, Harman, M, Dods, R, Chen, L, Bezerra, G, Demydchuk, Y, Stanway, S, Hyvonen, M.
Deposit date:2022-10-06
Release date:2023-09-20
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structure-Guided Chemical Optimization of Bicyclic Peptide ( Bicycle ) Inhibitors of Angiotensin-Converting Enzyme 2.
J.Med.Chem., 66, 2023
2H8N
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BU of 2h8n by Molmil
Structure of a glutamine-rich domain from histone deacetylase 4
Descriptor: Histone deacetylase 4
Authors:Guo, L, Han, A, Bates, D.L, Chen, L.
Deposit date:2006-06-07
Release date:2007-02-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3PA2
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BU of 3pa2 by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type Ley
Descriptor: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
Authors:Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
Deposit date:2010-10-18
Release date:2011-05-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
3PA1
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BU of 3pa1 by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type A
Descriptor: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
Authors:Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
Deposit date:2010-10-18
Release date:2011-05-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
3NQZ
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BU of 3nqz by Molmil
Crystal structure of the autoprocessed Vibriolysin MCP-02 with E369A mutation
Descriptor: CALCIUM ION, Secreted metalloprotease Mcp02, ZINC ION
Authors:Gao, X, Wang, J, Chen, L, Wu, J.-W, Zhang, Y.-Z.
Deposit date:2010-06-30
Release date:2010-10-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for the autoprocessing of zinc metalloproteases in the thermolysin family
Proc.Natl.Acad.Sci.USA, 107, 2010
1AAJ
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BU of 1aaj by Molmil
CRYSTAL STRUCTURE ANALYSIS OF AMICYANIN AND APOAMICYANIN FROM PARACOCCUS DENITRIFICANS AT 2.0 ANGSTROMS AND 1.8 ANGSTROMS RESOLUTION
Descriptor: AMICYANIN
Authors:Durley, R.C.E, Chen, L, Lim, L.W, Mathews, F.S.
Deposit date:1992-04-09
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure analysis of amicyanin and apoamicyanin from Paracoccus denitrificans at 2.0 A and 1.8 A resolution.
Protein Sci., 2, 1993
2E3V
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BU of 2e3v by Molmil
Crystal structure of the first fibronectin type III domain of neural cell adhesion molecule splicing isoform from human muscle culture lambda-4.4
Descriptor: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Nishino, A, Saijo, S, Kishishita, S, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-11-30
Release date:2007-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the first fibronectin type III domain of neural cell adhesion molecule splicing isoform from human muscle culture lambda-4.4
To be Published

221051

数据于2024-06-12公开中

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