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PDB: 621 件

8JTW
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hOCT1 in complex with nb5660 in inward facing partially open 1 conformation
分子名称: Solute carrier family 22 member 1, nanobody 56
著者Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X.
登録日2023-06-22
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
8JTZ
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hOCT1 in complex with spironolactone in outward facing partially occluded conformation
分子名称: SPIRONOLACTONE, Solute carrier family 22 member 1
著者Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X.
登録日2023-06-22
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Structural insights into human organic cation transporter 1 transport and inhibition.
Cell Discov, 10, 2024
4DGX
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BU of 4dgx by Molmil
LEOPARD Syndrome-Associated SHP2/Y279C mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Xu, J, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L.N, Liu, S.J, Zhang, Z.Y.
登録日2012-01-27
公開日2013-03-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Mechanistic Insights into LEOPARD Syndrome-Associated SHP2 Mutations.
J.Biol.Chem., 288, 2013
4DGP
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The wild-type Src homology 2 (SH2)-domain containing protein tyrosine phosphatase-2 (SHP2)
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Yu, Z.H, Xu, J, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L.N, Liu, S.J, Zhang, Z.Y.
登録日2012-01-26
公開日2013-03-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Mechanistic Insights into LEOPARD Syndrome-Associated SHP2 Mutations.
J.Biol.Chem., 288, 2013
3FKU
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Crystal structure of influenza hemagglutinin (H5) in complex with a broadly neutralizing antibody F10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Neutralizing antibody F10, ...
著者Hwang, W.C, Santelli, E, Stec, B, Wei, G, Cadwell, G, Bankston, L.A, Sui, J, Perez, S, Aird, D, Chen, L.M, Ali, M, Murakami, A, Yammanuru, A, Han, T, Cox, N, Donis, R.O, Liddington, R.C, Marasco, W.A.
登録日2008-12-17
公開日2009-02-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses.
Nat.Struct.Mol.Biol., 16, 2009
3NPH
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Crystal structure of the pfam00427 domain from Synechocystis sp. PCC 6803
分子名称: Phycobilisome 32.1 kDa linker polypeptide, phycocyanin-associated, rod 2
著者Gao, X, Chen, L, Wu, J.-W, Zhang, Y.-Z.
登録日2010-06-28
公開日2011-06-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Crystal structure of the N-terminal domain of linker L(R) and the assembly of cyanobacterial phycobilisome rods
Mol.Microbiol., 82, 2011
6NEB
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MYC Promoter G-Quadruplex with 1:6:1 loop length
分子名称: DNA (27-MER)
著者Dickerhoff, J, Onel, B, Chen, L, Chen, Y, Yang, D.
登録日2018-12-17
公開日2019-02-13
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution Structure of a MYC Promoter G-Quadruplex with 1:6:1 Loop Length.
Acs Omega, 4, 2019
3R2A
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Crystal structure of RXRalpha ligand-binding domain complexed with corepressor SMRT2 and antagonist rhein
分子名称: 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid, Nuclear receptor corepressor 2, Retinoic acid receptor RXR-alpha
著者Zhang, H, Chen, L, Chen, J, Jiang, H, Shen, X.
登録日2011-03-14
公開日2011-05-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for retinoic x receptor repression on the tetramer.
J.Biol.Chem., 286, 2011
3QRF
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Structure of a domain-swapped FOXP3 dimer
分子名称: Forkhead box protein P3, MAGNESIUM ION, Nuclear factor of activated T-cells, ...
著者Bandukwala, H.S, Wu, Y, Feurer, M, Chen, Y, Barbosa, B, Ghosh, S, Stroud, J.C, Benoist, C, Mathis, D, Rao, A, Chen, L.
登録日2011-02-17
公開日2011-04-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells.
Immunity, 34, 2011
1NLM
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BU of 1nlm by Molmil
CRYSTAL STRUCTURE OF MURG:GLCNAC COMPLEX
分子名称: GLYCEROL, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
著者Hu, Y, Chen, L, Ha, S, Gross, B, Falcone, B, Walker, D, Mokhtarzadeh, M, Walker, S.
登録日2003-01-07
公開日2003-02-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases
Proc.Natl.Acad.Sci.USA, 100, 2003
3G7N
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Crystal Structure of a Triacylglycerol Lipase from Penicillium Expansum at 1.3
分子名称: DI(HYDROXYETHYL)ETHER, Lipase, PENTAETHYLENE GLYCOL, ...
著者Bian, C.B, Yuan, C, Chen, L.Q, Edward, J.M, Lin, L, Jiang, L.G, Huang, Z.X, Huang, M.D.
登録日2009-02-10
公開日2010-02-23
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of a triacylglycerol lipase from Penicillium expansum at 1.3 A determined by sulfur SAD
Proteins, 78, 2010
2PK8
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Crystal structure of an uncharacterized protein PF0899 from Pyrococcus furiosus
分子名称: GOLD (I) CYANIDE ION, Uncharacterized protein PF0899
著者Liu, Z.J, Tempel, W, Chen, L, Shah, A, Lee, D, Clancy-Kelley, L.L, Dillard, B.D, Rose, J.P, Sugar, F.J, Jenny Jr, F.E, Lee, H.S, Izumi, M, Shah, C, Poole III, F.L, Adams, M.W.W, Richardson, J.S, Richardson, D.C, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2007-04-17
公開日2007-05-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of the hypothetical protein PF0899 from Pyrococcus furiosus at 1.85 A resolution.
Acta Crystallogr.,Sect.F, 63, 2007
2EB2
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BU of 2eb2 by Molmil
Crystal structure of mutated EGFR kinase domain (G719S)
分子名称: Epidermal growth factor receptor
著者Yoshikawa, S, Kukimoto-Niino, M, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Senba, K, Yamamoto, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-06
公開日2008-02-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor
Oncogene, 2012
2DYY
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BU of 2dyy by Molmil
Crystal structure of putative translation initiation inhibitor PH0854 from Pyrococcus horikoshii
分子名称: UPF0076 protein PH0854
著者Ihsanawati, Kishishita, S, Murayama, K, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Bessho, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-09-19
公開日2007-03-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of putative translation initiation inhibitor PH0854 from Pyrococcus horikoshii
To be Published
1AJB
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BU of 1ajb by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE D153G MUTANT OF E. COLI ALKALINE PHOSPHATASE: A MUTANT WITH WEAKER MAGNESIUM BINDING AND INCREASED CATALYTIC ACTIVITY
分子名称: ALKALINE PHOSPHATASE, MAGNESIUM ION, SULFATE ION, ...
著者Dealwis, C.G, Chen, L, Abad-Zapatero, C.
登録日1995-08-19
公開日1995-11-14
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献3-D structure of the D153G mutant of Escherichia coli alkaline phosphatase: an enzyme with weaker magnesium binding and increased catalytic activity.
Protein Eng., 8, 1995
1RYQ
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BU of 1ryq by Molmil
Putative DNA-directed RNA polymerase, subunit e'' from Pyrococcus Furiosus Pfu-263306-001
分子名称: DNA-directed RNA polymerase, subunit e'', ZINC ION
著者Liu, Z.-J, Chen, L, Tempel, W, Shah, A, Arendall III, W.B, Rose, J.P, Brereton, P.S, Izumi, M, Jenney Jr, F.E, Lee, H.S, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Richardson, D.C, Richardson, J.S, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2003-12-22
公開日2004-08-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Parameter-space screening: a powerful tool for high-throughput crystal structure determination.
Acta Crystallogr.,Sect.D, 61, 2005
1D8F
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CRYSTAL STRUCTURE OF MMP3 COMPLEXED WITH A PIPERAZINE BASED INHIBITOR.
分子名称: CALCIUM ION, N-HYDROXY-1-(4-METHOXYPHENYL)SULFONYL-4-BENZYLOXYCARBONYL-PIPERAZINE-2-CARBOXAMIDE, STROMELYSIN-1 PRECURSOR, ...
著者Cheng, M.Y, De, B, Pikul, S, Almstead, N.G, Natchus, M.G, Anastasio, M.V, McPhail, S.J, Snider, C.E, Taiwo, Y.O, Chen, L.Y.
登録日1999-10-22
公開日2000-10-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Design and synthesis of piperazine-based matrix metalloproteinase inhibitors.
J.Med.Chem., 43, 2000
3CQ2
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Structure of the DTDP-4-Keto-L-Rhamnose Reductase related protein (other form) from Thermus Thermophilus HB8
分子名称: Putative uncharacterized protein TTHB138
著者Jeyakanthan, J, Kanaujia, S.P, Sekar, K, Satoh, S, Kitamura, Y, Ebihara, A, Chen, L, Liu, Z.J, Wang, B.C, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-04-02
公開日2009-04-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the DTDP-4-Keto-L-Rhamnose Reductase related protein from Thermus Thermophilus HB8
To be Published
8B9P
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ACE2 in complex with bicyclic peptide inhibitor
分子名称: 1-[3,5-bis(3-bromanylpropanoyl)-1,3,5-triazinan-1-yl]-3-bromanyl-propan-1-one, ALA-CYS-GLY-ARG-GLN-PHE-CYS-HIS-THR-LEU-MET-PRO-ARG-HIS-LEU-CYS-ALA-NH2, Processed angiotensin-converting enzyme 2
著者Brear, P, Lulla, A, Harman, M, Dods, R, Chen, L, Bezerra, G, Demydchuk, Y, Stanway, S, Hyvonen, M.
登録日2022-10-06
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structure-Guided Chemical Optimization of Bicyclic Peptide ( Bicycle ) Inhibitors of Angiotensin-Converting Enzyme 2.
J.Med.Chem., 66, 2023
2H8N
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Structure of a glutamine-rich domain from histone deacetylase 4
分子名称: Histone deacetylase 4
著者Guo, L, Han, A, Bates, D.L, Chen, L.
登録日2006-06-07
公開日2007-02-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3PA2
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Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type Ley
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-10-18
公開日2011-05-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
3PA1
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Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type A
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-10-18
公開日2011-05-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
3NQZ
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BU of 3nqz by Molmil
Crystal structure of the autoprocessed Vibriolysin MCP-02 with E369A mutation
分子名称: CALCIUM ION, Secreted metalloprotease Mcp02, ZINC ION
著者Gao, X, Wang, J, Chen, L, Wu, J.-W, Zhang, Y.-Z.
登録日2010-06-30
公開日2010-10-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for the autoprocessing of zinc metalloproteases in the thermolysin family
Proc.Natl.Acad.Sci.USA, 107, 2010
1AAJ
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CRYSTAL STRUCTURE ANALYSIS OF AMICYANIN AND APOAMICYANIN FROM PARACOCCUS DENITRIFICANS AT 2.0 ANGSTROMS AND 1.8 ANGSTROMS RESOLUTION
分子名称: AMICYANIN
著者Durley, R.C.E, Chen, L, Lim, L.W, Mathews, F.S.
登録日1992-04-09
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure analysis of amicyanin and apoamicyanin from Paracoccus denitrificans at 2.0 A and 1.8 A resolution.
Protein Sci., 2, 1993
2E3V
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Crystal structure of the first fibronectin type III domain of neural cell adhesion molecule splicing isoform from human muscle culture lambda-4.4
分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Nishino, A, Saijo, S, Kishishita, S, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-11-30
公開日2007-06-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the first fibronectin type III domain of neural cell adhesion molecule splicing isoform from human muscle culture lambda-4.4
To be Published

221051

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