2E8V
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with product GGPP (P21) | 分子名称: | GERANYLGERANYL DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase | 著者 | Chen, C.K.-M, Guo, R.T, Ko, T.P, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-23 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2Z78
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with BPH-806 | 分子名称: | 3-(decyloxy)-5-(3,5-difluorophenyl)-1-(2,2-diphosphonoethyl)pyridinium, Geranylgeranyl pyrophosphate synthetase | 著者 | Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-08-16 | 公開日 | 2008-07-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
|
|
2Z4V
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and GGPP (inhibitory site) | 分子名称: | GERANYLGERANYL DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION | 著者 | Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-06-26 | 公開日 | 2008-07-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
|
|
2Z4W
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-749 | 分子名称: | Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, [(6E,11E)-2,6,12,16-tetramethylheptadeca-2,6,11,15-tetraene-9,9-diyl]bis(phosphonic acid) | 著者 | Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-06-26 | 公開日 | 2008-07-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
|
|
2ZYS
| A. Fulgidus lipase with fatty acid fragment and chloride | 分子名称: | CHLORIDE ION, Lipase, putative, ... | 著者 | Chen, C.K, Ko, T.P, Guo, R.T, Wang, A.H. | 登録日 | 2009-01-29 | 公開日 | 2009-06-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of the alkalohyperthermophilic Archaeoglobus fulgidus lipase contains a unique C-terminal domain essential for long-chain substrate binding. J.Mol.Biol., 390, 2009
|
|
2ZYI
| A. Fulgidus lipase with fatty acid fragment and calcium | 分子名称: | CALCIUM ION, Lipase, putative, ... | 著者 | Chen, C.K, Ko, T.P, Guo, R.T, Wang, A.H. | 登録日 | 2009-01-22 | 公開日 | 2009-06-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the alkalohyperthermophilic Archaeoglobus fulgidus lipase contains a unique C-terminal domain essential for long-chain substrate binding. J.Mol.Biol., 390, 2009
|
|
2ZYH
| mutant A. Fulgidus lipase S136A complexed with fatty acid fragment | 分子名称: | CALCIUM ION, HEXADECANE, Lipase, ... | 著者 | Chen, C.K, Ko, T.P, Guo, R.T, Wang, A.H. | 登録日 | 2009-01-22 | 公開日 | 2009-06-16 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Structure of the alkalohyperthermophilic Archaeoglobus fulgidus lipase contains a unique C-terminal domain essential for long-chain substrate binding. J.Mol.Biol., 390, 2009
|
|
2Z4Y
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-252 | 分子名称: | (1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID), Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION | 著者 | Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-06-26 | 公開日 | 2008-07-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
|
|
2Z4Z
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-sc01 | 分子名称: | (6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID), Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION | 著者 | Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-06-26 | 公開日 | 2008-07-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
|
|
2ZYR
| A. Fulgidus lipase with fatty acid fragment and magnesium | 分子名称: | Lipase, putative, MAGNESIUM ION, ... | 著者 | Chen, C.K, Ko, T.P, Guo, R.T, Wang, A.H. | 登録日 | 2009-01-28 | 公開日 | 2009-06-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structure of the alkalohyperthermophilic Archaeoglobus fulgidus lipase contains a unique C-terminal domain essential for long-chain substrate binding. J.Mol.Biol., 390, 2009
|
|
3KP4
| |
3KP5
| |
3KP6
| Staphylococcus epidermidis TcaR in complex with salicylate | 分子名称: | 2-HYDROXYBENZOIC ACID, CACODYLATE ION, Transcriptional regulator TcaR | 著者 | Chang, Y.M, Chen, C.K, Yeh, Y.J, Wang, A.H. | 登録日 | 2009-11-15 | 公開日 | 2010-09-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
3KP3
| Staphylococcus epidermidis in complex with ampicillin | 分子名称: | (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, Transcriptional regulator TcaR | 著者 | Chang, Y.M, Chen, C.K, Wang, A.H. | 登録日 | 2009-11-15 | 公開日 | 2010-06-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
2Z7H
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with inhibitor BPH-210 | 分子名称: | Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, {1-HYDROXY-3-[METHYL(4-PHENYLBUTYL)AMINO]PROPANE-1,1-DIYL}BIS(PHOSPHONIC ACID) | 著者 | Cao, R, Chen, C.K.-M, Guo, R.-T, Hudock, M, Wang, A.H.-J, Oldfield, E. | 登録日 | 2007-08-23 | 公開日 | 2008-05-06 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structures of a potent phenylalkyl bisphosphonate inhibitor bound to farnesyl and geranylgeranyl diphosphate synthases. Proteins, 73, 2008
|
|
2E8T
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium, FsPP and IPP | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, ... | 著者 | Guo, R.T, Ko, T.P, Chen, C.K.-M, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-23 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2E8W
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and IPP | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION | 著者 | Guo, R.T, Ko, T.P, Chen, C.K.-M, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-24 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2E90
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium, pyrophosphate and FPP | 分子名称: | FARNESYL DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, ... | 著者 | Guo, R.T, Ko, T.P, Chen, C.K.-M, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-24 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2E95
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-675 | 分子名称: | 1-HYDROXY-2-[3'-(NAPHTHALENE-2-SULFONYLAMINO)-BIPHENYL-3-YL]ETHYLIDENE-1,1-BISPHOSPHONIC ACID, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION | 著者 | Guo, R.T, Cao, R, Ko, T.P, Jeng, W.Y, Chang, T.H, Chen, C.K.-M, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-24 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2E94
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-364 | 分子名称: | 3-BIPHENYL-3-YL-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION | 著者 | Guo, R.T, Ko, T.P, Cao, R, Chen, C.K.-M, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-24 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2E8U
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and IPP (P21) | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION | 著者 | Guo, R.T, Chen, C.K.-M, Ko, T.P, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-23 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2E91
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-91 | 分子名称: | Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, ZOLEDRONIC ACID | 著者 | Guo, R.T, Ko, T.P, Cao, R, Chen, C.K.-M, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-24 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2E8X
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and GPP | 分子名称: | GERANYL DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION | 著者 | Guo, R.T, Ko, T.P, Chen, C.K.-M, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-24 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2E93
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with BPH-629 | 分子名称: | Geranylgeranyl pyrophosphate synthetase, [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID | 著者 | Guo, R.T, Cao, R, Ko, T.P, Chen, C.K.-M, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-24 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2E92
| S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-261 | 分子名称: | (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION | 著者 | Guo, R.T, Ko, T.P, Cao, R, Jeng, W.Y, Chen, C.K.-M, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-24 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|