2E8T

S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium, FsPP and IPP

Summary for 2E8T

Entry DOI	10.2210/pdb2e8t/pdb
Related	2DH4 2E8U 2E8V 2E8W 2E8X 2E90 2E91 2E92 2E93 2E94 2E95 2E96 2E97
Descriptor	Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ... (5 entities in total)
Functional Keywords	prenyltransferase, farnesyl pyrophosphate, bisphosphonate, transferase
Biological source	Saccharomyces cerevisiae (baker's yeast)
Cellular location	Cytoplasm (By similarity): Q12051
Total number of polymer chains	2
Total formula weight	79984.31
Authors	Guo, R.T.,Ko, T.P.,Chen, C.K.-M.,Jeng, W.Y.,Chang, T.H.,Liang, P.H.,Oldfield, E.,Wang, A.H.-J. (deposition date: 2007-01-23, release date: 2007-06-12, Last modification date: 2023-10-25)
Primary citation	Guo, R.T.,Cao, R.,Liang, P.H.,Ko, T.P.,Chang, T.H.,Hudock, M.P.,Jeng, W.Y.,Chen, C.K.-M.,Zhang, Y.,Song, Y.,Kuo, C.J.,Yin, F.,Oldfield, E.,Wang, A.H.-J. Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104:10022-10027, 2007 Cited by PubMed: 17535895 DOI: 10.1073/pnas.0702254104 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.13 Å)

Structure validation