2E8T

S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium, FsPP and IPP

Summary for 2E8T

Related2DH4 2E8U 2E8V 2E8W 2E8X 2E90 2E91 2E92 2E93 2E94 2E95 2E96 2E97
DescriptorGeranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ... (5 entities in total)
Functional Keywordsprenyltransferase, farnesyl pyrophosphate, bisphosphonate, transferase
Biological sourceSaccharomyces cerevisiae (baker's yeast)
Cellular locationCytoplasm (By similarity) Q12051
Total number of polymer chains2
Total molecular weight79984.31
Authors
Guo, R.T.,Ko, T.P.,Chen, C.K.-M.,Jeng, W.Y.,Chang, T.H.,Liang, P.H.,Oldfield, E.,Wang, A.H.-J. (deposition date: 2007-01-23, release date: 2007-06-12, Last modification date: 2011-07-13)
Primary citation
Guo, R.T.,Cao, R.,Liang, P.H.,Ko, T.P.,Chang, T.H.,Hudock, M.P.,Jeng, W.Y.,Chen, C.K.-M.,Zhang, Y.,Song, Y.,Kuo, C.J.,Yin, F.,Oldfield, E.,Wang, A.H.-J.
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104:10022-10027, 2007
PubMed: 17535895 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.0702254104
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.13 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.252200.2%3.2%5.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution