2E8X

S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and GPP

Summary for 2E8X
Related2DH4 2E8T 2E8U 2E8V 2E8W 2E90 2E91 2E92 2E93 2E94 2E95 2E96 2E97
DescriptorGeranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, GERANYL DIPHOSPHATE, ... (4 entities in total)
Functional Keywordsprenyltransferase, farnesyl pyrophosphate, bisphosphonate, transferase
Biological sourceSaccharomyces cerevisiae (baker's yeast)
Cellular locationCytoplasm (By similarity): Q12051
Total number of polymer chains2
Total formula weight79323.76
Authors
Guo, R.T.,Ko, T.P.,Chen, C.K.-M.,Jeng, W.Y.,Chang, T.H.,Liang, P.H.,Oldfield, E.,Wang, A.H.-J. (deposition date: 2007-01-24, release date: 2007-06-12, Last modification date: 2011-07-13)
Primary citationCao, R.,Chang, T.H.,Chen, C.K.-M.,Guo, R.T.,Hudock, M.P.,Jeng, W.Y.,Ko, T.P.,Kuo, C.J.,Liang, P.H.,Oldfield, E.,Song, Y.,Wang, A.H.-J.,Yin, F.,Zhang, Y.
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104:10022-10027, 2007
PubMed: 17535895
DOI: 110.1073/pnas.0702254104
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.04 Å)
Structure validation
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PDB entries from 2021-06-16