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PDB: 22 件
7N69
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BU of 7n69 by Molmil
Pre-fusion state 2 of EEEV with localized reconstruction
分子名称: Spike glycoprotein E1, Spike glycoprotein E2
著者Chen, C.-L, Kuhn, R.J, Klose, T.
登録日2021-06-07
公開日2022-06-22
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (14.1 Å)
主引用文献Cryo-EM structures of alphavirus conformational intermediates in low pH-triggered prefusion states.
Proc.Natl.Acad.Sci.USA, 119, 2022
7N6A
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BU of 7n6a by Molmil
Pre-fusion state 1 of EEEV with localized reconstruction
分子名称: Spike glycoprotein E1, Spike glycoprotein E2
著者Chen, C.-L, Kuhn, R.J, Klose, T.
登録日2021-06-07
公開日2022-06-22
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (14.3 Å)
主引用文献Cryo-EM structures of alphavirus conformational intermediates in low pH-triggered prefusion states.
Proc.Natl.Acad.Sci.USA, 119, 2022
7SJ4
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BU of 7sj4 by Molmil
Human Trio residues 1284-1959 in complex with Rac1
分子名称: Ras-related C3 botulinum toxin substrate 1, Triple functional domain protein
著者Chen, C.-L, Ravala, S.K, Bandekar, S.J, Cash, J, Tesmer, J.J.G.
登録日2021-10-15
公開日2022-07-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1.
J.Biol.Chem., 298, 2022
8SO9
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BU of 8so9 by Molmil
Phosphoinositide phosphate 3 kinase gamma
分子名称: Phosphoinositide 3-kinase regulatory subunit 5, phosphatidylinositol-4,5-bisphosphate 3-kinase
著者Chen, C.-L, Tesmer, J.J.G.
登録日2023-04-28
公開日2024-04-03
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 31, 2024
8SOA
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BU of 8soa by Molmil
Phosphoinositide phosphate 3 kinase gamma bound with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Phosphoinositide 3-kinase regulatory subunit 5, phosphatidylinositol-4,5-bisphosphate 3-kinase
著者Chen, C.-L, Tesmer, J.J.G.
登録日2023-04-28
公開日2024-04-03
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 31, 2024
8SOE
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Phosphoinositide phosphate 3 kinase gamma bound with ADP and two Gbetagamma subunits in State 2
分子名称: ADENOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Chen, C.-L, Tesmer, J.J.G.
登録日2023-04-28
公開日2024-04-03
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 31, 2024
8SOD
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BU of 8sod by Molmil
Phosphoinositide phosphate 3 kinase gamma bound with ADP and two Gbetagamma subunits in State 1
分子名称: ADENOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Chen, C.-L, Tesmer, J.J.G.
登録日2023-04-28
公開日2024-04-03
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 31, 2024
8SOC
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BU of 8soc by Molmil
Phosphoinositide phosphate 3 kinase gamma bound with ADP and Gbetagamma
分子名称: ADENOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Chen, C.-L, Tesmer, J.J.G.
登録日2023-04-28
公開日2024-04-03
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 31, 2024
8SOB
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BU of 8sob by Molmil
Phosphoinositide phosphate 3 kinase gamma bound with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Phosphoinositide 3-kinase regulatory subunit 5, phosphatidylinositol-4,5-bisphosphate 3-kinase
著者Chen, C.-L, Tesmer, J.J.G.
登録日2023-04-28
公開日2024-04-03
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular basis for G beta gamma-mediated activation of phosphoinositide 3-kinase gamma.
Nat.Struct.Mol.Biol., 31, 2024
5GSQ
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BU of 5gsq by Molmil
Crystal structure of IgG Fc with a homogeneous glycoform and Antibody-Dependent Cellular Cytotoxicity
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, C.-L, Hsu, J.-C, Lin, C.-W, Wu, C.-Y, Wong, C.-H, Ma, C.
登録日2016-08-17
公開日2017-06-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of a Homogeneous IgG-Fc Glycoform with the N-Glycan Designed to Maximize the Antibody Dependent Cellular Cytotoxicity
ACS Chem. Biol., 12, 2017
7MTB
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BU of 7mtb by Molmil
Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab6
分子名称: Fab6 heavy chain, Fab6 light chain, RETINAL, ...
著者Chen, Q, Chen, C.-L, Tesmer, J.J.G.
登録日2021-05-13
公開日2021-07-07
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
7MT8
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BU of 7mt8 by Molmil
Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin
分子名称: RETINAL, Rhodopsin, Rhodopsin kinase GRK1, ...
著者Chen, Q, Chen, C.-L, Tesmer, J.J.G.
登録日2021-05-13
公開日2021-07-07
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
7MTA
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BU of 7mta by Molmil
Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab1
分子名称: Fab1 Heavy chain, Fab1 Light chain, RETINAL, ...
著者Chen, Q, Chen, C.-L, Tesmer, J.J.G.
登録日2021-05-13
公開日2021-07-07
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
7MT9
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BU of 7mt9 by Molmil
Rhodopsin kinase (GRK1) in complex with rhodopsin
分子名称: RETINAL, Rhodopsin, Rhodopsin kinase GRK1, ...
著者Chen, Q, Chen, C.-L, Tesmer, J.J.G.
登録日2021-05-13
公開日2021-07-07
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
5V2M
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BU of 5v2m by Molmil
Mevalonate diphosphate mediated ATP binding mechanism of the mevalonate diphosphate decarboxylase from Enterococcus faecalis
分子名称: Mevalonate diphosphate decarboxylase, SULFATE ION
著者Stauffacher, C.V, Chen, C.-L.
登録日2017-03-05
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.989 Å)
主引用文献Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis.
J. Biol. Chem., 292, 2017
5V2L
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BU of 5v2l by Molmil
Mevalonate diphosphate mediated ATP binding mechanism of the mevalonate diphosphate decarboxylase from Enterococcus faecalis
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Mevalonate diphosphate decarboxylase, PHOSPHATE ION
著者Stauffacher, C.V, Chen, C.-L.
登録日2017-03-05
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis.
J. Biol. Chem., 292, 2017
6E2S
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BU of 6e2s by Molmil
apo form of MDDEF with buffer exchange
分子名称: Mevalonate diphosphate decarboxylase, SULFATE ION
著者Stauffacher, C.V, Chen, C.-L.
登録日2018-07-12
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.791 Å)
主引用文献Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase.
Nat Commun, 11, 2020
6E2T
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BU of 6e2t by Molmil
MDDEF in complex with MVAPP
分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, Mevalonate diphosphate decarboxylase
著者Stauffacher, C.V, Chen, C.-L.
登録日2018-07-12
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.692 Å)
主引用文献Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase.
Nat Commun, 11, 2020
6E2U
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BU of 6e2u by Molmil
MDDEF in complex with MVAPP, AMPPCP and Magnesium
分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, MAGNESIUM ION, Mevalonate diphosphate decarboxylase, ...
著者Stauffacher, C.V, Chen, C.-L.
登録日2018-07-12
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase.
Nat Commun, 11, 2020
6E2W
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BU of 6e2w by Molmil
MDDEF in complex with MVAPP, ADP, sulfate and cobalt
分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, ...
著者Stauffacher, C.V, Chen, C.-L.
登録日2018-07-12
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase.
Nat Commun, 11, 2020
6E2V
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BU of 6e2v by Molmil
MDDEF in complex with MVAPP, ADPBeF3 and magnesium
分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
著者Stauffacher, C.V, Chen, C.-L.
登録日2018-07-12
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase.
Nat Commun, 11, 2020
6E2Y
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BU of 6e2y by Molmil
MDDEF in complex with MVAPP, ADP, sulfate and cobalt. Anomalous data
分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, ...
著者Stauffacher, C.V, Chen, C.-L.
登録日2018-07-12
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase.
Nat Commun, 11, 2020

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