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PDB: 727 results

3SQE
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BU of 3sqe by Molmil
Crystal structure of prethrombin-2 mutant S195A in the alternative form
Descriptor: GLYCEROL, Thrombin light chain, heavy chain
Authors:Pozzi, N, Chen, Z, Di Cera, E.
Deposit date:2011-07-05
Release date:2011-11-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of prethrombin-2 reveal alternative conformations under identical solution conditions and the mechanism of zymogen activation.
Biochemistry, 50, 2011
3CX6
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BU of 3cx6 by Molmil
Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein alpha-13 subunit, MAGNESIUM ION, ...
Authors:Sprang, S.R, Chen, Z.
Deposit date:2008-04-23
Release date:2008-10-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Recognition of the Activated States of Galpha13 by the rgRGS Domain of PDZRhoGEF.
Structure, 16, 2008
1GG4
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BU of 1gg4 by Molmil
CRYSTAL STRUCTURE OF ESCHERICHIA COLI UDPMURNAC-TRIPEPTIDE D-ALANYL-D-ALANINE-ADDING ENZYME (MURF) AT 2.3 ANGSTROM RESOLUTION
Descriptor: UDP-N-ACETYLMURAMOYLALANYL-D-GLUTAMYL-2,6-DIAMINOPIMELATE-D-ALANYL-D-ALANYL LIGASE
Authors:Yan, Y, Munshi, S, Chen, Z.
Deposit date:2000-07-12
Release date:2000-12-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of Escherichia coli UDPMurNAc-tripeptide d-alanyl-d-alanine-adding enzyme (MurF) at 2.3 A resolution.
J.Mol.Biol., 304, 2000
1T8P
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BU of 1t8p by Molmil
Crystal structure of Human erythrocyte 2,3-bisphosphoglycerate mutase
Descriptor: Bisphosphoglycerate mutase
Authors:Wang, Y, Wei, Z, Bian, Q, Cheng, Z, Wan, M, Liu, L, Gong, W.
Deposit date:2004-05-13
Release date:2004-08-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human bisphosphoglycerate mutase
J.Biol.Chem., 279, 2004
4TQ9
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BU of 4tq9 by Molmil
Crystal Structure of a GDP-bound G12V Oncogenic Mutant of Human GTPase KRas
Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Hunter, J.C, Manandhar, A, Gurbani, D, Chen, Z, Westover, K.D.
Deposit date:2014-06-10
Release date:2015-06-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.491 Å)
Cite:Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations.
Mol Cancer Res., 13, 2015
3S6P
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BU of 3s6p by Molmil
Crystal Structure of Helicoverpa Armigera Stunt Virus
Descriptor: CALCIUM ION, CHLORIDE ION, Capsid protein
Authors:Speir, J.A, Chen, Z, Taylor, D.J, Johnson, J.E.
Deposit date:2011-05-25
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Helicoverpa armigera stunt virus
To be Published
3SJI
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BU of 3sji by Molmil
crystal structure of CVA16 3C in complex with Rupintrivir (AG7088)
Descriptor: 3C protease, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, SODIUM ION
Authors:Lu, G, Qi, J, Chen, Z, Xu, X, Gao, F, Lin, D, Qian, W, Liu, H, Jiang, H, Yan, J, Gao, G.F.
Deposit date:2011-06-21
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design.
J.Virol., 85, 2011
4TQA
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BU of 4tqa by Molmil
Crystal Structure of a GDP-bound G13D Oncogenic Mutant of Human GTPase KRas
Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Hunter, J.C, Manandhar, A, Gurbani, D, Chen, Z, Westover, K.D.
Deposit date:2014-06-10
Release date:2015-06-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations.
Mol Cancer Res., 13, 2015
2PKA
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BU of 2pka by Molmil
REFINED 2 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF PORCINE PANCREATIC KALLIKREIN A, A SPECIFIC TRYPSIN-LIKE SERINE PROTEINASE. CRYSTALLIZATION, STRUCTURE DETERMINATION, CRYSTALLOGRAPHIC REFINEMENT, STRUCTURE AND ITS COMPARISON WITH BOVINE TRYPSIN
Descriptor: BENZAMIDINE, KALLIKREIN A
Authors:Bode, W, Chen, Z.
Deposit date:1984-05-21
Release date:1984-07-19
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Refined 2 A X-ray crystal structure of porcine pancreatic kallikrein A, a specific trypsin-like serine proteinase. Crystallization, structure determination, crystallographic refinement, structure and its comparison with bovine trypsin.
J.Mol.Biol., 164, 1983
3GIC
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BU of 3gic by Molmil
Structure of thrombin mutant delta(146-149e) in the free form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombin heavy chain, Thrombin light chain
Authors:Bah, A, Carrell, C.J, Chen, Z, Gandhi, P.S, Di Cera, E.
Deposit date:2009-03-05
Release date:2009-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Stabilization of the E* form turns thrombin into an anticoagulant.
J.Biol.Chem., 284, 2009
2LKK
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BU of 2lkk by Molmil
Human L-FABP in complex with oleate
Descriptor: Fatty acid-binding protein, liver, OLEIC ACID
Authors:Cai, J, Luecke, C, Chen, Z, Qiao, Y, Klimtchuk, E.S, Hamilton, J.A.
Deposit date:2011-10-13
Release date:2012-06-20
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure and backbone dynamics of human liver fatty acid binding protein: fatty acid binding revisited.
Biophys.J., 102, 2012
5E7R
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BU of 5e7r by Molmil
Crystal structure of TL10-81 bound to TAK1-TAB1
Descriptor: 2-chloro-N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}acetamide, TAK1 kinase - TAB1 chimera fusion protein
Authors:Gurbani, D, Hunter, J.C, Tan, L, Chen, Z, Westover, K.D.
Deposit date:2015-10-13
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structure-guided development of covalent TAK1 inhibitors.
Bioorg. Med. Chem., 25, 2017
2MLD
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BU of 2mld by Molmil
Solution structure of BmKTX-D19K/K6D
Descriptor: Potassium channel toxin alpha-KTx 3.6
Authors:Hong, J, Lin, D, Chen, Z, Wu, Y.
Deposit date:2014-02-24
Release date:2015-02-25
Method:SOLUTION NMR
Cite:SOLUTION STRUCTURE of BMKTX-D19K
To be Published
5CL1
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BU of 5cl1 by Molmil
Complex structure of Norrin with human Frizzled 4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4, Maltose-binding periplasmic protein,Norrin
Authors:Wang, Z, Ke, J, Shen, G, Cheng, Z, Xu, H.E, Xu, W.
Deposit date:2015-07-16
Release date:2015-08-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of the Norrin-Frizzled 4 interaction.
Cell Res., 25, 2015
2OV0
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BU of 2ov0 by Molmil
Structure of the blue copper protein Amicyanin to 0.75 A resolution
Descriptor: Amicyanin, COPPER (II) ION, PHOSPHATE ION, ...
Authors:Carrell, C.J, Davidson, V.L, Chen, Z, Cunane, L.M, Trickey, P, Mathews, F.S.
Deposit date:2007-02-12
Release date:2007-08-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (0.75 Å)
Cite:Ultrahigh resolution studies of amicyanin
TO BE PUBLISHED
7V27
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BU of 7v27 by Molmil
RBD/XG005 local refinement
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, XG005-VH, ...
Authors:Zhan, W.Q, Zhang, X, Sun, L, Chen, Z.G.
Deposit date:2021-08-07
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (4.18 Å)
Cite:RBD/XG005 local refinement
To Be Published
5V8F
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BU of 5v8f by Molmil
Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1
Descriptor: Cell division control protein 6, Cell division cycle protein CDT1, DNA (39-MER), ...
Authors:Yuan, Z, Riera, A, Bai, L, Sun, J, Spanos, C, Chen, Z.A, Barbon, M, Rappsilber, J, Stillman, B, Speck, C, Li, H.
Deposit date:2017-03-21
Release date:2017-05-10
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.
Nat. Struct. Mol. Biol., 24, 2017
2P5B
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BU of 2p5b by Molmil
The complex structure of JMJD2A and trimethylated H3K36 peptide
Descriptor: FE (II) ION, Histone H3, JmjC domain-containing histone demethylation protein 3A, ...
Authors:Zhang, G, Chen, Z, Zang, J, Hong, X, Shi, Y.
Deposit date:2007-03-14
Release date:2007-06-12
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural basis of the recognition of a methylated histone tail by JMJD2A.
Proc.Natl.Acad.Sci.USA, 104, 2007
2PMV
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BU of 2pmv by Molmil
Crystal Structure of Human Intrinsic Factor- Cobalamin Complex at 2.6 A Resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COBALAMIN, Gastric intrinsic factor
Authors:Mathews, F.S, Gordon, M.M, Chen, Z, Rajashankar, K.R, Ealick, S.E, Alpers, D.H, Sukumar, N.
Deposit date:2007-04-23
Release date:2007-10-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human intrinsic factor: Cobalamin complex at 2.6-A resolution
Proc.Natl.Acad.Sci.USA, 104, 2007
3KPQ
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BU of 3kpq by Molmil
Crystal Structure of HLA B*4405 in complex with EEYLKAWTF, a mimotope
Descriptor: Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ...
Authors:Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J.
Deposit date:2009-11-16
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
3KUN
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BU of 3kun by Molmil
X-ray structure of the metcyano form of dehaloperoxidase from amphitrite ornata: evidence for photoreductive lysis of iron-cyanide bond
Descriptor: CYANIDE ION, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Serrano, V.S, Chen, Z, Gaff, J.F, Rose, R, Franzen, S.
Deposit date:2009-11-27
Release date:2010-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:X-ray structure of the metcyano form of dehaloperoxidase from Amphitrite ornata: evidence for photoreductive dissociation of the iron-cyanide bond.
Acta Crystallogr.,Sect.D, 66, 2010
2QFK
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BU of 2qfk by Molmil
X-ray Crystal Structure Analysis of the Binding Site in the Ferric and Oxyferrous Forms of the Recombinant Heme Dehaloperoxidase Cloned from Amphitrite ornata
Descriptor: AMMONIUM ION, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:de Serrano, V.S, Chen, Z, Davis, M.F, Franzen, S.
Deposit date:2007-06-27
Release date:2008-07-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:X-ray crystal structural analysis of the binding site in the ferric and oxyferrous forms of the recombinant heme dehaloperoxidase cloned from Amphitrite ornata
Acta Crystallogr.,Sect.D, 63, 2007
2MLA
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BU of 2mla by Molmil
Solution structure of BmKTX-D19K
Descriptor: Potassium channel toxin alpha-KTx 3.6
Authors:Hong, J, Lin, D, Chen, Z, Wu, Y.
Deposit date:2014-02-21
Release date:2015-02-25
Method:SOLUTION NMR
Cite:Solution structure of BmKTX-D19K
To be Published
2R9E
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BU of 2r9e by Molmil
The structure of the binary complex of citryl dethia COA and citrate synthase from the thermophilic archaeonthermoplasma acidophilum
Descriptor: Citrate synthase, s-citryldethia Coenzyme A
Authors:Lehmann, C, Chen, Z.
Deposit date:2007-09-12
Release date:2008-09-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Snapshots of Intermediates in the Condensation Reaction Catalyzed by Citrate Synthase
To be Published
5TO3
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BU of 5to3 by Molmil
Crystal structure of thrombin mutant W215A/E217A fused to EGF456 of thrombomodulin via a 31-residue linker and bound to PPACK
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
Authors:Barranco-Medina, S, Murphy, M, Pelc, L, Chen, Z, Di Cera, E, Pozzi, N.
Deposit date:2016-10-16
Release date:2017-03-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Rational Design of Protein C Activators.
Sci Rep, 7, 2017

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数据于2024-09-04公开中

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