3Q1M
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![BU of 3q1m by Molmil](/molmil-images/mine/3q1m) | Crystal Structure of BmrR Dimer bound to DNA and the ligand 4-amino-quinaldine | Descriptor: | 2-methylquinolin-4-amine, 23 bp promoter DNA, Multidrug-efflux transporter 1 regulator | Authors: | Bachas, S, Eginton, C, Gunio, G, Wade, H. | Deposit date: | 2010-12-17 | Release date: | 2011-06-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
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1AZM
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3P7X
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![BU of 3p7x by Molmil](/molmil-images/mine/3p7x) | Crystal structure of an atypical two-cysteine peroxiredoxin (SAOUHSC_01822) from Staphylococcus aureus NCTC8325 | Descriptor: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Probable thiol peroxidase, ... | Authors: | Bhattacharyya, S, Dutta, D, Ghosh, A.K, Das, A.K. | Deposit date: | 2010-10-13 | Release date: | 2011-10-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal structure of an atypical two-cysteine peroxiredoxin (SAOUHSC_01822) from Staphylococcus aureus NCTC8325 To be Published
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3OR7
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![BU of 3or7 by Molmil](/molmil-images/mine/3or7) | On the structural basis of modal gating behavior in K+channels - E71I | Descriptor: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | Authors: | Chakrapani, S, Cordero-Morales, J.F, Jogini, V, Pan, A.C, Cortes, D.M, Roux, B, Perozo, E. | Deposit date: | 2010-09-06 | Release date: | 2011-01-05 | Last modified: | 2018-08-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | On the structural basis of modal gating behavior in K(+) channels. Nat.Struct.Mol.Biol., 18, 2011
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1CZM
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1YD9
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![BU of 1yd9 by Molmil](/molmil-images/mine/1yd9) | 1.6A Crystal Structure of the Non-Histone Domain of the Histone Variant MacroH2A1.1. | Descriptor: | Core histone macro-H2A.1, GOLD ION | Authors: | Chakravarthy, S, Swamy, G.Y.S.K, Caron, C, Perche, P.Y, Pehrson, J.R, Khochbin, S, Luger, K. | Deposit date: | 2004-12-23 | Release date: | 2005-09-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural characterization of the histone variant macroH2A Mol.Cell.Biol., 25, 2005
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3Q2Y
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![BU of 3q2y by Molmil](/molmil-images/mine/3q2y) | Crystal Structure of BmrR bound to ethidium | Descriptor: | 23 bp promoter, ETHIDIUM, GLYCEROL, ... | Authors: | Bachas, S, Eginton, C, Gunio, G, Wade, H. | Deposit date: | 2010-12-20 | Release date: | 2011-06-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
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3Q3D
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![BU of 3q3d by Molmil](/molmil-images/mine/3q3d) | Crystal structure of BmrR bound to puromycin | Descriptor: | BmrR promoter DNA, Multidrug-efflux transporter 1 regulator, PUROMYCIN | Authors: | Bachas, S, Eginton, C, Gunio, G, Wade, H. | Deposit date: | 2010-12-21 | Release date: | 2011-06-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
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3EKN
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![BU of 3ekn by Molmil](/molmil-images/mine/3ekn) | Insulin receptor kinase complexed with an inhibitor | Descriptor: | 2-fluoro-6-{[2-({2-methoxy-4-[4-(1-methylethyl)piperazin-1-yl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide, Insulin receptor | Authors: | Chamberlain, S, Atkins, C, Deanda, F, Dumble, M, Gerding, R, Groy, A, Korenchuk, S, Kumar, R, Lei, H, Mook, R, Moorthy, G, Redman, A, Rowland, J, Shewchuk, L. | Deposit date: | 2008-09-19 | Release date: | 2008-12-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity. Bioorg.Med.Chem.Lett., 19, 2009
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3Q4H
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![BU of 3q4h by Molmil](/molmil-images/mine/3q4h) | Crystal structure of the Mycobacterium smegmatis EsxGH complex (MSMEG_0620-MSMEG_0621) | Descriptor: | Low molecular weight protein antigen 7, Pe family protein | Authors: | Chan, S, Harris, L, Kuo, E, Ahn, C, Zhou, T.T, Nguyen, L, Shin, A, Sawaya, M.R, Cascio, D, Arbing, M.A, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-12-23 | Release date: | 2011-01-26 | Last modified: | 2014-05-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. Plos One, 8, 2013
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3PFP
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![BU of 3pfp by Molmil](/molmil-images/mine/3pfp) | Structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis in complex with an active site inhibitor | Descriptor: | (2R)-2,7-bis(phosphonooxy)heptanoic acid, (2S)-2,7-bis(phosphonooxy)heptanoic acid, CHLORIDE ION, ... | Authors: | Reichau, S, Jiao, W, Walker, S.R, Hutton, R.D, Parker, E.J, Baker, E.N. | Deposit date: | 2010-10-28 | Release date: | 2011-03-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Potent inhibitors of a shikimate pathway enzyme from Mycobacterium tuberculosis: combining mechanism- and modeling-based design J.Biol.Chem., 286, 2011
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3Q5P
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![BU of 3q5p by Molmil](/molmil-images/mine/3q5p) | Crystal structure of BmrR bound to Tetracycline | Descriptor: | 23 bp BmrR promoter DNA, GLYCEROL, Multidrug-efflux transporter 1 regulator, ... | Authors: | Bachas, S, Eginton, C, Gunio, G, Wade, H. | Deposit date: | 2010-12-29 | Release date: | 2011-06-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.942 Å) | Cite: | Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
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3Q5R
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![BU of 3q5r by Molmil](/molmil-images/mine/3q5r) | Crystal structure of BmrR bound to Kanamycin | Descriptor: | 23 bp promoter DNA, KANAMYCIN A, Multidrug-efflux transporter 1 regulator | Authors: | Bachas, S, Eginton, C, Gunio, G, Wade, H. | Deposit date: | 2010-12-29 | Release date: | 2011-07-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
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3QMF
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![BU of 3qmf by Molmil](/molmil-images/mine/3qmf) | Crystal strucuture of an inositol monophosphatase family protein (SAS2203) from Staphylococcus aureus MSSA476 | Descriptor: | Inositol monophosphatase family protein, SULFATE ION | Authors: | Bhattacharyya, S, Dutta, D, Ghosh, A.K, Das, A.K. | Deposit date: | 2011-02-04 | Release date: | 2012-01-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of Staphylococcal dual specific inositol monophosphatase/NADP(H) phosphatase (SAS2203) delineates the molecular basis of substrate specificity Biochimie, 94, 2012
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3Q5S
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![BU of 3q5s by Molmil](/molmil-images/mine/3q5s) | Crystal structure of BmrR bound to Acetylcholine | Descriptor: | 23 bp promoter DNA, ACETYLCHOLINE, GLYCEROL, ... | Authors: | Bachas, S, Eginton, C, Gunio, G, Wade, H. | Deposit date: | 2010-12-29 | Release date: | 2011-06-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
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4I3E
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![BU of 4i3e by Molmil](/molmil-images/mine/4i3e) | Crystal structure of Staphylococcal IMPase - I complexed with products. | Descriptor: | GLYCEROL, Inositol monophosphatase family protein, MAGNESIUM ION, ... | Authors: | Bhattacharyya, S, Dutta, A, Dutta, D, Das, A.K. | Deposit date: | 2012-11-26 | Release date: | 2013-12-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of Staphylococcal IMPase - I complexed with products. To be Published
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2IFF
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![BU of 2iff by Molmil](/molmil-images/mine/2iff) | |
2DR0
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1X9X
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![BU of 1x9x by Molmil](/molmil-images/mine/1x9x) | Solution Structure of Dimeric SAM Domain from MAPKKK Ste11 | Descriptor: | Serine/threonine-protein kinase STE11 | Authors: | Bhattacharjya, S, Xu, P, Gingras, R, Shaykhutdinov, R, Wu, C, Whiteway, M, Ni, F. | Deposit date: | 2004-08-24 | Release date: | 2005-08-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the dimeric SAM domain of MAPKKK Ste11 and its interactions with the adaptor protein Ste50 from the budding yeast: implications for Ste11 activation and signal transmission through the Ste50-Ste11 complex. J.Mol.Biol., 344, 2004
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1C8M
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![BU of 1c8m by Molmil](/molmil-images/mine/1c8m) | REFINED CRYSTAL STRUCTURE OF HUMAN RHINOVIRUS 16 COMPLEXED WITH VP63843 (PLECONARIL), AN ANTI-PICORNAVIRAL DRUG CURRENTLY IN CLINICAL TRIALS | Descriptor: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, HUMAN RHINOVIRUS 16 COAT PROTEIN, ZINC ION | Authors: | Chakravarty, S, Bator, C.M, Pevear, D.C, Diana, G.D, Rossmann, M.G. | Deposit date: | 2000-05-26 | Release date: | 2000-11-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | THE REFINED STRUCTURE OF A PICORNAVIRUS INHIBITOR CURRENTLY IN CLINICAL TRIALS, WHEN COMPLEXED WITH HUMAN RHINOVIRUS 16 to be published
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3G4E
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3FXE
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![BU of 3fxe by Molmil](/molmil-images/mine/3fxe) | |
2KJD
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![BU of 2kjd by Molmil](/molmil-images/mine/2kjd) | |
1BLE
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4LRG
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![BU of 4lrg by Molmil](/molmil-images/mine/4lrg) | Structure of BRD4 bromodomain 1 with a dimethyl thiophene isoxazole azepine carboxamide | Descriptor: | 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-[1,2]oxazolo[5,4-c]thieno[2,3-e]azepin-6-yl]acetamide, Bromodomain-containing protein 4 | Authors: | Ravichandran, S, Jayaram, H, Poy, F, Gehling, V, Hewitt, M, Vaswani, R, Leblanc, Y, Cote, A, Nasveschuk, C, Taylor, A, Harmange, J.-C, Audia, J, Pardo, E, Joshi, S, Sandy, P, Mertz, J, Sims, R, Bergeron, L, Bryant, B, Yellapuntala, S, Nandana, B.S, Birudukota, S, Albrecht, B, Bellon, S. | Deposit date: | 2013-07-19 | Release date: | 2013-08-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors. ACS Med Chem Lett, 4, 2013
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