1AZM
DRUG-PROTEIN INTERACTIONS: STRUCTURE OF SULFONAMIDE DRUG COMPLEXED WITH HUMAN CARBONIC ANHYDRASE I
Summary for 1AZM
Entry DOI | 10.2210/pdb1azm/pdb |
Descriptor | CARBONIC ANHYDRASE I, ZINC ION, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, ... (4 entities in total) |
Functional Keywords | protein-drug interactions, oxo-acid lyase, sulfonamides, lyase(oxo-acid) |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00915 |
Total number of polymer chains | 1 |
Total formula weight | 29062.64 |
Authors | Chakravarty, S.,Kannan, K.K. (deposition date: 1993-11-28, release date: 1994-04-30, Last modification date: 2024-02-07) |
Primary citation | Chakravarty, S.,Kannan, K.K. Drug-protein interactions. Refined structures of three sulfonamide drug complexes of human carbonic anhydrase I enzyme. J.Mol.Biol., 243:298-309, 1994 Cited by PubMed: 7932756DOI: 10.1006/jmbi.1994.1655 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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