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PDB: 42 件

7ZAP
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BU of 7zap by Molmil
Solution structure of RBM39 RRM1 bound to U1 snRNA stem loop 3
分子名称: RNA-binding protein 39, U1 snRNA SL3
著者Campagne, S, Allain, F.H.
登録日2022-03-22
公開日2023-03-29
最終更新日2023-09-20
実験手法SOLUTION NMR
主引用文献Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39.
Nat Commun, 14, 2023
6SNJ
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BU of 6snj by Molmil
Solution structure of the FUS/TLS RNA recognition motif in complex with U1 snRNA stem loop III
分子名称: RNA-binding protein FUS, U1 snRNA stem loop III, RNA (28-MER)
著者Campagne, S, Allain, F.H.
登録日2019-08-26
公開日2020-10-28
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Nat Commun, 11, 2020
5IEJ
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BU of 5iej by Molmil
Solution structure of the BeF3-activated conformation of SdrG from Pseudomonas melonis Fr1
分子名称: SdrG
著者Campagne, S, Vorholt, J.A, Allain, F.H.-T.
登録日2016-02-25
公開日2016-07-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Role of the PFXFATG[G/Y] Motif in the Activation of SdrG, a Response Regulator Involved in the Alphaproteobacterial General Stress Response.
Structure, 24, 2016
5IEB
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BU of 5ieb by Molmil
Solution structure of SdrG from Sphingomonas melonis Fr1
分子名称: Sensory transduction regulatory protein
著者Campagne, S, Vorholt, J.A, Allain, F.H.-T.
登録日2016-02-25
公開日2016-07-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Role of the PFXFATG[G/Y] Motif in the Activation of SdrG, a Response Regulator Involved in the Alphaproteobacterial General Stress Response.
Structure, 24, 2016
7AEP
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BU of 7aep by Molmil
Solution structure of U1-A RRM2 (190-282)
分子名称: U1 small nuclear ribonucleoprotein A
著者Campagne, S, Allain, F.H.
登録日2020-09-18
公開日2021-02-03
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献An in vitro reconstituted U1 snRNP allows the study of the disordered regions of the particle and the interactions with proteins and ligands.
Nucleic Acids Res., 49, 2021
6HMI
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BU of 6hmi by Molmil
Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7
分子名称: RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Campagne, S, Allain, F.H.
登録日2018-09-12
公開日2019-08-14
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural basis of a small molecule targeting RNA for a specific splicing correction.
Nat.Chem.Biol., 15, 2019
6HMO
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BU of 6hmo by Molmil
Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7 in complex with the SMN-C5 splicing modifier
分子名称: 2-(8-fluoranyl-2-methyl-imidazo[1,2-a]pyridin-6-yl)-7-(4-methylpiperazin-1-yl)pyrido[1,2-a]pyrimidin-4-one, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Campagne, S, Allain, F.H.
登録日2018-09-12
公開日2019-08-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis of a small molecule targeting RNA for a specific splicing correction.
Nat.Chem.Biol., 15, 2019
7Q33
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BU of 7q33 by Molmil
Solution structure of RBM39 RRM2 bound to 5'-AGCUUUG-3
分子名称: RNA (5'-R(*AP*GP*CP*UP*UP*UP*G)-3'), RNA-binding protein 39
著者Campagne, S, Allain, F.H.
登録日2021-10-26
公開日2023-02-08
最終更新日2023-09-20
実験手法SOLUTION NMR
主引用文献Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39.
Nat Commun, 14, 2023
5OR0
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BU of 5or0 by Molmil
NMR derived model of the 5'-splice site of SMN2 in complex with the 5'-end of U1 snRNA
分子名称: RNA (5'-R(P*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Campagne, S, Clery, A, Allain, F.H.
登録日2017-08-14
公開日2017-08-30
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers.
Nat Commun, 8, 2017
5OR5
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BU of 5or5 by Molmil
NMR structure of the complex formed by an engineered region 2 of sigmaE in complex with GTAAAA
分子名称: DNA (5'-D(*GP*TP*AP*AP*AP*A)-3'), ECF RNA polymerase sigma-E factor,ECF RNA polymerase sigma factor SigW,ECF RNA polymerase sigma-E factor
著者Campagne, S, Vorholt, J.A, Allain, F.H.
登録日2017-08-15
公開日2018-06-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Engineered promoter selectivity of an ECF sigma factor
Not published
2NB9
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BU of 2nb9 by Molmil
Solution structure of ZitP zinc finger
分子名称: Uncharacterized protein, ZINC ION
著者Campagne, S, Berge, M, Viollier, P.H, Allain, F.H.-T.
登録日2016-02-01
公開日2016-12-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Modularity and determinants of a (bi-)polarization control system from free-living and obligate intracellular bacteria.
Elife, 5, 2016
4LUP
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BU of 4lup by Molmil
Crystal structure of the complex formed by region of E. coli sigmaE bound to its -10 element non template strand
分子名称: 1,2-ETHANEDIOL, RNA polymerase sigma factor, region 2 of sigmaE of E. coli
著者Campagne, S, Marsh, M.E, Vorholt, J.A.V, Allain, F.H.-T, Capitani, G.
登録日2013-07-25
公開日2014-02-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural basis for -10 promoter element melting by environmentally induced sigma factors.
Nat.Struct.Mol.Biol., 21, 2014
2LFW
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BU of 2lfw by Molmil
NMR structure of the PhyRSL-NepR complex from Sphingomonas sp. Fr1
分子名称: NepR anti sigma factor, PhyR sigma-like domain
著者Campagne, S, Damberger, F.F, Vorholt, J.A, Allain, F.H.-T.
登録日2011-07-18
公開日2012-04-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for sigma factor mimicry in the general stress response of Alphaproteobacteria.
Proc.Natl.Acad.Sci.USA, 109, 2012
2KO0
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BU of 2ko0 by Molmil
Solution structure of the THAP zinc finger of THAP1 in complex with its DNA target
分子名称: RRM1, THAP domain-containing protein 1, ZINC ION
著者Campagne, S, Gervais, V, Saurel, O, Milon, A.
登録日2009-09-08
公開日2010-01-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural determinants of specific DNA-recognition by the THAP zinc finger
Nucleic Acids Res., 2010
2MAO
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BU of 2mao by Molmil
NMR structure of region 2 of E. coli sigmaE
分子名称: RNA polymerase sigma factor
著者Campagne, S, Vorholt, J.A, Allain, F.H.-T.
登録日2013-07-16
公開日2014-02-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for -10 promoter element melting by environmentally induced sigma factors.
Nat.Struct.Mol.Biol., 21, 2014
2L1G
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BU of 2l1g by Molmil
RDC refined solution structure of the THAP zinc finger of THAP1 in complex with its 16bp RRM1 DNA target
分子名称: DNA (5'-D(*GP*CP*TP*TP*GP*TP*GP*TP*GP*GP*GP*CP*AP*GP*CP*G)-3'), DNA (5'-D(P*CP*GP*CP*TP*GP*CP*CP*CP*AP*CP*AP*CP*AP*AP*GP*C)-3'), THAP domain-containing protein 1, ...
著者Campagne, S, Gervais, V, Saurel, O, Milon, A.
登録日2010-07-28
公開日2010-09-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献RDC refined solution structure of the THAP zinc finger of THAP1 in complex with its 16bp RRM1 DNA target
To be published
2JOS
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BU of 2jos by Molmil
Solution structure of piscidin in presence of DPC micelles
分子名称: Moronecidin
著者Campagna, S, Saint, N, Molle, G, Aumelas, A.
登録日2007-03-21
公開日2007-04-03
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Structure and mechanism of action of the antimicrobial peptide piscidin
Biochemistry, 46, 2007
2MAP
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BU of 2map by Molmil
Solution structure of the complex formed by the region 2 of E. coli sigmaE and its cognate -10 promoter element non template strand TGTCAAA.
分子名称: DNA, RNA polymerase sigma factor
著者Campagne, S, Vorholt, J.A, Allain, F.H.-T.
登録日2013-07-16
公開日2014-02-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for -10 promoter element melting by environmentally induced sigma factors.
Nat.Struct.Mol.Biol., 21, 2014
3BEW
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BU of 3bew by Molmil
10mer Crystal Structure of chicken MHC class I haplotype B21
分子名称: 10-mer from Tubulin beta-6 chain, Beta-2-microglobulin, Major histocompatibility complex class I glycoprotein haplotype B21
著者Koch, M, Camp, S, Collen, T, Avila, D, Salomonsen, J, Wallny, H.J, van Hateren, A, Hunt, L, Jacob, J.P, Johnston, F, Marston, D.A, Shaw, I, Dunbar, P.R, Cerundolo, V, Jones, E.Y, Kaufman, J.
登録日2007-11-20
公開日2008-01-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of an MHC class I molecule from b21 chickens illustrate promiscuous Peptide binding
Immunity, 27, 2007
3SWY
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BU of 3swy by Molmil
CNGA3 626-672 containing CLZ domain
分子名称: Cyclic nucleotide-gated cation channel alpha-3
著者Shuart, N.G, Haitin, Y, Camp, S.S, Black, K.D, Zagotta, W.N.
登録日2011-07-14
公開日2011-09-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular mechanism for 3:1 subunit stoichiometry of rod cyclic nucleotide-gated ion channels.
Nat Commun, 2, 2011
3SWF
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BU of 3swf by Molmil
CNGA1 621-690 containing CLZ domain
分子名称: ZINC ION, cGMP-gated cation channel alpha-1
著者Shuart, N.G, Haitin, Y, Camp, S.S, Black, K.D, Zagotta, W.N.
登録日2011-07-13
公開日2011-09-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Molecular mechanism for 3:1 subunit stoichiometry of rod cyclic nucleotide-gated ion channels.
Nat Commun, 2, 2011
4EQF
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BU of 4eqf by Molmil
Trip8b-1a#206-567 interacting with the carboxy-terminal seven residues of HCN2
分子名称: PEX5-related protein, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
著者Bankston, J.R, Camp, S.S, Dimaio, F, Lewis, A.S, Chetkovich, D.M, Zagotta, W.N.
登録日2012-04-18
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels.
Proc.Natl.Acad.Sci.USA, 109, 2012
8R63
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BU of 8r63 by Molmil
Solution structure of branaplam bound to the RNA duplex formed upon 5'-splice site recognition
分子名称: 5-(1~{H}-pyrazol-4-yl)-2-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]phenol, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Malard, F, Campagne, S.
登録日2023-11-20
公開日2024-03-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design.
Nucleic Acids Res., 52, 2024
8R62
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BU of 8r62 by Molmil
Solution structure of Risdiplam bound to the RNA duplex formed upon 5'-splice site recognition
分子名称: 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-1~{H}-pyrido[1,2-a]pyrimidin-4-one, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Malard, F, Campagne, S.
登録日2023-11-20
公開日2024-03-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design.
Nucleic Acids Res., 52, 2024
7P08
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BU of 7p08 by Molmil
Solution structure of the human SF3A1 ubiquitin-like domain
分子名称: Isoform 1 of Splicing factor 3A subunit 1
著者de Vries, T, Campagne, S, Allain, F.H.T.
登録日2021-06-29
公開日2022-02-09
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Sequence-specific RNA recognition by an RGG motif connects U1 and U2 snRNP for spliceosome assembly.
Proc.Natl.Acad.Sci.USA, 119, 2022

 

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