2KO0

Solution structure of the THAP zinc finger of THAP1 in complex with its DNA target

Summary for 2KO0

• Entry DOI: 10.2210/pdb2ko0/pdb
• Related: 2JTG
• NMR Information: BMRB: 16485
• Descriptor: THAP domain-containing protein 1, RRM1, ZINC ION, ... (4 entities in total)
• Functional Keywords: zinc finger, protein-dna complex, dna binding domain, transcription factor, ccch, coiled coil, dna-binding, metal-binding, nucleus, zinc-finger, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus, nucleoplasm: Q9NVV9
• Total number of polymer chains: 3
• Total formula weight: 20054.53

Authors

Campagne, S.,Gervais, V.,Saurel, O.,Milon, A. (deposition date: 2009-09-08, release date: 2010-01-19, Last modification date: 2021-11-10)

• Primary citation: Campagne, S.,Saurel, O.,Gervais, V.,Milon, A.; Structural determinants of specific DNA-recognition by the THAP zinc finger; Nucleic Acids Res., 2010; PubMed: 20144952; DOI: 10.1093/nar/gkq053

Experimental method

SOLUTION NMR