2KO0
Solution structure of the THAP zinc finger of THAP1 in complex with its DNA target
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THAP domain-containing protein 1 | polymer | 87 | 10189.8 | 1 | UniProt (Q9NVV9) Pfam (PF05485) | Homo sapiens (Human) | |
| 2 | B (B) | RRM1 | polymer | 16 | 4986.2 | 1 | |||
| 3 | C (C) | ZINC ION | polymer | 16 | 4813.1 | 1 | |||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A: 1 - 82 (UniProt: Q9NVV9)
| PDB | External Database | Details |
|---|---|---|
| Ser 62 | Cys 62 | engineered mutation |
| Ser 67 | Cys 67 | engineered mutation |
| Glu 83 | - | expression tag |
| Leu 84 | - | expression tag |
| Val 85 | - | expression tag |
| Pro 86 | - | expression tag |
| Arg 87 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 19989.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 20054.5 |
