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PDB: 27 件
7UW3
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Structure of SARS-CoV-2 Nucleocapsid Protein N-Terminal Domain
分子名称: Nucleoprotein
著者Calero, G.
登録日2022-05-02
公開日2023-05-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Atomic-Resolution Structure of SARS-CoV-2 Nucleocapsid Protein N-Terminal Domain.
J.Am.Chem.Soc., 144, 2022
8FSL
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Human Mesothelin bound to a neutralizing VH domain antibody
分子名称: Mesothelin, VH domain
著者Calero, G.
登録日2023-01-10
公開日2024-05-29
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Preclinical assessment of a novel human antibody VH domain targeting mesothelin as an antibody-drug conjugate.
Mol Ther Oncolytics, 31, 2023
5JK7
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The X-ray structure of the DDB1-DCAF1-Vpr-UNG2 complex
分子名称: DNA damage-binding protein 1, Protein VPRBP, Protein Vpr, ...
著者Calero, G, Ahn, J, Wu, Y.
登録日2016-04-26
公開日2016-10-05
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction.
Nat.Struct.Mol.Biol., 23, 2016
9BVT
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RNA Pol II - High Mn(+2) concentration
分子名称: DNA (5'-D(P*AP*CP*GP*TP*CP*CP*CP*TP*CP*TP*CP*GP*A)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
著者Calero, G.
登録日2024-05-20
公開日2024-10-02
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser.
Proc.Natl.Acad.Sci.USA, 121, 2024
9BW0
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RNA Polymerase II - No ATP
分子名称: DNA (5'-D(P*AP*CP*GP*TP*CP*CP*CP*TP*CP*TP*CP*GP*A)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
著者Calero, G.
登録日2024-05-20
公開日2024-10-02
実験手法X-RAY DIFFRACTION (3.51 Å)
主引用文献Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser.
Proc.Natl.Acad.Sci.USA, 121, 2024
1PJA
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The crystal structure of palmitoyl protein thioesterase-2 reveals the basis for divergent substrate specificities of the two lysosomal thioesterases (PPT1 and PPT2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Palmitoyl-protein thioesterase 2 precursor
著者Calero, G, Gupta, P, Nonato, M.C, Tandel, S, Biehl, E.R, Hofmann, S.L, Clardy, J.
登録日2003-06-02
公開日2003-09-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2.
J.Biol.Chem., 278, 2003
6OI7
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Se-Met structure of apo- Escherichia coli dGTPase
分子名称: Deoxyguanosinetriphosphate triphosphohydrolase, MANGANESE (II) ION, SULFATE ION
著者Calero, G, Barnes, C.O, Wu, Y.
登録日2019-04-08
公開日2019-05-29
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Proc.Natl.Acad.Sci.USA, 116, 2019
1N52
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Cap Binding Complex
分子名称: 20 kDa nuclear cap binding protein, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, 80 kDa nuclear cap binding protein, ...
著者Calero, G, Wilson, K, Ly, T, Rios-Steiner, J, Clardy, J, Cerione, R.
登録日2002-11-04
公開日2003-02-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural basis of m7GpppG binding to the nuclear cap-binding protein complex.
Nat.Struct.Biol., 9, 2002
1N54
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Cap Binding Complex m7GpppG free
分子名称: 20 kDa nuclear cap binding protein, 80 kDa nuclear cap binding protein, GLYCEROL
著者Calero, G, Wilson, K, Ly, T, Rios-Steiner, J, Clardy, J, Cerione, R.
登録日2002-11-04
公開日2003-02-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural basis of m7GpppG binding to the nuclear cap-binding protein complex.
Nat.Struct.Biol., 9, 2002
7SD4
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BU of 7sd4 by Molmil
SARS-CoV-2 Nucleocapsid N-terminal domain (N-NTD) protein
分子名称: Nucleoprotein
著者Sarkar, S, Runge, B, Russell, R.W, Calero, D, Zeinalilathori, S, Quinn, C.M, Lu, M, Calero, G, Gronenborn, A.M, Polenova, T.
登録日2021-09-29
公開日2022-06-08
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Atomic-Resolution Structure of SARS-CoV-2 Nucleocapsid Protein N-Terminal Domain.
J.Am.Chem.Soc., 144, 2022
5C4J
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Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
登録日2015-06-18
公開日2015-08-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
5C4A
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Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Barnes, C.O, Calero, M, Malik, I, Saphr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
登録日2015-06-17
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
5C4X
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Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
登録日2015-06-18
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
5C3E
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BU of 5c3e by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
登録日2015-06-17
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
5C44
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BU of 5c44 by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
登録日2015-06-17
公開日2015-08-26
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
8U9R
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STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION USING A FREE-ELECTRON LASER
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*AP*CP*GP*TP*CP*CP*CP*TP*CP*TP*CP*GP*A)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Arjunan, P, Calero, G, Kaplan, C.D.
登録日2023-09-20
公開日2024-09-18
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U9X
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STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION AT 3.0 A OF T834P MUTANT USING A FREE-ELECTRON LASER
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
著者Arjunan, P, Calero, G, Kaplan, C.D.
登録日2023-09-20
公開日2024-09-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser.
Proc.Natl.Acad.Sci.USA, 121, 2024
3RJ1
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BU of 3rj1 by Molmil
Architecture of the Mediator Head module
分子名称: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ...
著者Imasaki, T, Calero, G, Cai, G, Tsai, K.L, Yamada, K, Cardelli, F, Erdjument-Bromage, H, Tempst, P, Berger, I, Kornberg, G.L, Asturias, F.J, Kornberg, R.D, Takagi, Y.
登録日2011-04-14
公開日2011-07-27
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Architecture of the Mediator head module.
Nature, 475, 2011
2QRZ
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Cdc42 bound to GMP-PCP: Induced Fit by Effector is Required
分子名称: Cell division control protein 42 homolog precursor, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Phillips, M.J, Calero, G, Chan, B, Cerione, R.A.
登録日2007-07-30
公開日2008-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Effector Proteins Exert an Important Influence on the Signaling-active State of the Small GTPase Cdc42.
J.Biol.Chem., 283, 2008
4Z8L
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BU of 4z8l by Molmil
Crystal structure of DCAF1/SIV-MND VPX/MND SAMHD1 NTD ternary complex
分子名称: Protein VPRBP, SAM domain and HD domain-containing protein, Vpx protein, ...
著者Koharudin, L.M, Wu, Y, Calero, G, Ahn, J, Gronenborn, A.M.
登録日2015-04-09
公開日2015-06-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile alpha Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.
J.Biol.Chem., 290, 2015
3H0G
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RNA Polymerase II from Schizosaccharomyces pombe
分子名称: DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
著者Spahr, H, Calero, G, Bushnell, D.A, Kornberg, R.D.
登録日2009-04-09
公開日2009-08-25
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution.
Proc.Natl.Acad.Sci.USA, 106, 2009
3K7A
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Crystal Structure of an RNA polymerase II-TFIIB complex
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Liu, X, Bushnell, D.A, Wang, D, Calero, G, Kornberg, R.D.
登録日2009-10-12
公開日2009-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism.
Science, 327, 2010
6XQJ
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Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A
分子名称: Protein Vpr,UV excision repair protein RAD23 homolog A, ZINC ION
著者Byeon, I.-J.L, Calero, G, Wu, Y, Byeon, C.H, Gronenborn, A.M.
登録日2020-07-09
公開日2021-11-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A.
Nat Commun, 12, 2021
6OIX
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Structure of Escherichia coli dGTPase bound to GTP
分子名称: Deoxyguanosinetriphosphate triphosphohydrolase, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION
著者Barnes, C.O, Wu, Y, Calero, G.
登録日2019-04-09
公開日2019-05-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OIY
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Structure of Escherichia coli bound to dGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxyguanosinetriphosphate triphosphohydrolase, MANGANESE (II) ION
著者Barnes, C.O, Wu, Y, Calero, G.
登録日2019-04-09
公開日2019-05-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Proc.Natl.Acad.Sci.USA, 116, 2019

 

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