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PDB: 41 件

2JG7
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Crystal structure of Seabream Antiquitin and Elucidation of its substrate specificity
分子名称: ANTIQUITIN, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Tang, W.K, Wong, K.B, Cha, S.S, Lee, H.S, Cheng, C.H.K, Fong, W.P.
登録日2007-02-09
公開日2008-05-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献The Crystal Structure of Seabream Antiquitin Reveals the Structural Basis of its Substrate Specificity.
FEBS Lett., 582, 2008
5E26
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Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ...
著者DONG, A, LOPPNAU, P, RAVICHANDRAN, M, CHENG, C, TEMPEL, W, SEITOVA, A, HUTCHINSON, A, HONG, B.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, Structural Genomics Consortium (SGC)
登録日2015-09-30
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate
to be published
4JVA
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Crystal Structure of RIIbeta(108-402) bound to HE33, a N6 di-propyl substituted cAMP analog
分子名称: (2R,4aR,6R,7R,7aS)-6-[6-(dipropylamino)-9H-purin-9-yl]tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide, cAMP-dependent protein kinase type II-beta regulatory subunit
著者Brown, S.H.J, Cheng, C.Y, Saldanha, A.S, Wu, J, Cottam, H, Sankaran, B, Taylor, S.S.
登録日2013-03-25
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs.
Acs Chem.Biol., 8, 2013
3HY4
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Structure of human MTHFS with N5-iminium phosphate
分子名称: 5-formyltetrahydrofolate cyclo-ligase, MAGNESIUM ION, N-({trans-4-[({(2R,4R,4aS,6S,8aS)-2-amino-4-hydroxy-5-[(phosphonooxy)methyl]decahydropteridin-6-yl}methyl)amino]cyclohexyl}carbonyl)-L-glutamic acid, ...
著者Wu, D, Li, Y, Song, G, Cheng, C, Shaw, N, Liu, Z.-J.
登録日2009-06-22
公開日2009-07-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.795 Å)
主引用文献Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues
Cancer Res., 69, 2009
3HY6
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Structure of human MTHFS with ADP
分子名称: 5-formyltetrahydrofolate cyclo-ligase, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Wu, D, Li, Y, Song, G, Cheng, C, Shaw, N, Liu, Z.-J.
登録日2009-06-22
公開日2009-07-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues
Cancer Res., 69, 2009
3HY3
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Structure of human MTHFS with 10-formyltetrahydrofolate
分子名称: 5-formyltetrahydrofolate cyclo-ligase, MAGNESIUM ION, N-({4-[{[(2R,4S,4aR,6S,8aS)-2-amino-4-hydroxydecahydropteridin-6-yl]methyl}(formyl)amino]phenyl}carbonyl)-D-glutamic acid, ...
著者Wu, D, Li, Y, Song, G, Cheng, C, Shaw, N, Liu, Z.-J.
登録日2009-06-22
公開日2009-07-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues
Cancer Res., 69, 2009
3ECR
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Structure of human porphobilinogen deaminase
分子名称: 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase
著者Song, G, Li, Y, Cheng, C, Zhao, Y, Gao, A, Zhang, R, Joachimiak, A, Shaw, N, Liu, Z.J.
登録日2008-09-01
公開日2008-09-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.182 Å)
主引用文献Structural insight into acute intermittent porphyria.
Faseb J., 23, 2009
4I2U
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Crystal structure of the reduced glutaredoxin from Chlorella sorokiniana T-89 in complex with glutathione
分子名称: GLUTATHIONE, glutaredoxin
著者Nien, C.-Y, Cheng, C.-Y, Shaw, J.-F, Chen, Y.-T, Liu, J.-H.
登録日2012-11-23
公開日2013-11-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure and functional analysis of glutaredoxin from Chlorella sorokiniana T-89
To be Published
6JLI
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Crystal structure of CTLD7 domain of human PLA2R
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Secretory phospholipase A2 receptor
著者Yu, B, Hu, Z, Kong, D, Cheng, C, He, Y.
登録日2019-03-06
公開日2019-07-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.778 Å)
主引用文献Crystal structure of the CTLD7 domain of human M-type phospholipase A2 receptor.
J.Struct.Biol., 207, 2019
4I2T
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Crystal structure of the oxidized glutaredoxin from Chlorella sorokiniana T-89
分子名称: glutaredoxin
著者Nien, C.-Y, Cheng, C.-Y, Shaw, J.-F, Chen, Y.-T, Liu, J.-H.
登録日2012-11-22
公開日2013-11-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure and functional analysis of glutaredoxin from Chlorella sorokiniana T-89
To be Published
6KYC
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Structure of the S207A mutant of Clostridium difficile sortase B
分子名称: Putative peptidase C60B, sortase B
著者Kang, C.Y, Huang, I.H, Wu, T.Y, Chang, J.C, Hsiao, Y.Y, Cheng, C.H, Tsai, W.J, Hsu, K.C, Wang, S.Y.
登録日2019-09-17
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Functional analysis ofClostridium difficilesortase B reveals key residues for catalytic activity and substrate specificity.
J.Biol.Chem., 295, 2020
6KYD
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Structure of the R217A mutant of Clostridium difficile sortase B
分子名称: Putative peptidase C60B, sortase B
著者Kang, C.Y, Huang, I.H, Wu, T.Y, Chang, J.C, Hsiao, Y.Y, Cheng, C.H, Tsai, W.J, Hsu, K.C, Wang, S.Y.
登録日2019-09-18
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Functional analysis ofClostridium difficilesortase B reveals key residues for catalytic activity and substrate specificity.
J.Biol.Chem., 295, 2020
4JV4
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Crystal Structure of RIalpha(91-379) bound to HE33, a N6 di-propyl substituted cAMP analog
分子名称: (2R,4aR,6R,7R,7aS)-6-[6-(dipropylamino)-9H-purin-9-yl]tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide, cAMP-dependent protein kinase type I-alpha regulatory subunit
著者Brown, S.H.J, Cheng, C.Y, Saldanha, A.S, Wu, J, Cottam, H, Sankaran, B, Taylor, S.S.
登録日2013-03-25
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.952 Å)
主引用文献Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs.
Acs Chem.Biol., 8, 2013
3NV7
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Crystal structure of H.pylori phosphopantetheine adenylyltransferase mutant I4V/N76Y
分子名称: ACETIC ACID, Phosphopantetheine adenylyltransferase, SULFATE ION
著者Chen, C.H, Cheng, C.S, Yin, H.S.
登録日2010-07-08
公開日2011-07-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of H.pylori phosphopantetheine adenylyltransferase mutant I4V/N76Y
To be Published
3HXT
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Structure of human MTHFS
分子名称: 5-formyltetrahydrofolate cyclo-ligase, MAGNESIUM ION, NICKEL (II) ION
著者Wu, D, Li, Y, Song, G, Cheng, C, Zhang, R, Joachimiak, A, Shaw, N, Liu, Z.-J.
登録日2009-06-22
公開日2009-07-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues
Cancer Res., 69, 2009
8HBC
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Crystal structure of the CysR-CTLD3 fragment of human DEC205
分子名称: Lymphocyte antigen 75
著者Kong, D, Yu, B, Hu, Z, Cheng, C, Cao, L, He, Y.
登録日2022-10-28
公開日2023-11-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Interaction of human dendritic cell receptor DEC205/CD205 with keratins.
J.Biol.Chem., 300, 2024
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