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3ECR

Structure of human porphobilinogen deaminase

Summary for 3ECR
Entry DOI10.2210/pdb3ecr/pdb
DescriptorPorphobilinogen deaminase, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid (3 entities in total)
Functional Keywordshuman porphobilinogen deaminase, heme biosynthesis, porphobilinogen hinge, alternative splicing, cytoplasm, disease mutation, porphyrin biosynthesis, transferase
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm (Probable): P08397
Total number of polymer chains2
Total formula weight80151.37
Authors
Song, G.,Li, Y.,Cheng, C.,Zhao, Y.,Gao, A.,Zhang, R.,Joachimiak, A.,Shaw, N.,Liu, Z.J. (deposition date: 2008-09-01, release date: 2008-09-30, Last modification date: 2024-03-20)
Primary citationSong, G.,Li, Y.,Cheng, C.,Zhao, Y.,Gao, A.,Zhang, R.,Joachimiak, A.,Shaw, N.,Liu, Z.J.
Structural insight into acute intermittent porphyria.
Faseb J., 23:396-404, 2009
Cited by
PubMed: 18936296
DOI: 10.1096/fj.08-115469
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.182 Å)
Structure validation

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