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3ECR

Structure of human porphobilinogen deaminase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Porphobilinogen deaminasepolymer36439655.32UniProt (P08397)
Pfam (PF01379)
Pfam (PF03900)
Homo sapiens (Human)PBG-D, Pre-uroporphyrinogen synthase, Hydroxymethylbilane synthase, HMBS
2C, D
(A, B)
3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acidnon-polymer420.42Chemie (DPM)
3E, F
(A, B)
waterwater18.0137Chemie (HOH)
Sequence modifications
A, B: 4 - 364 (UniProt: P08397)
PDBExternal DatabaseDetails
Ser 1-expression tag
Asn 2-expression tag
Ala 3-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight79310.5
Non-Polymers*Number of molecules2
Total formula weight840.8
All*Total formula weight80151.4
*Water molecules are not included.

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PDB entries from 2025-12-24

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