5GJC
 
 | | Zika virus NS3 helicase in complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, NS3 helicase | | 著者 | Tian, H.L, Ji, X.Y, Yang, X.Y, Zhang, Z.X, Lu, Z.K, Yang, K.L, Chen, C, Zhao, Q, Chi, H, Mu, Z.Y, Xie, W, Wang, Z.F, Lou, H.Q, Yang, H.T, Rao, Z.H. | | 登録日 | 2016-06-28 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | | 主引用文献 | Structural basis of Zika virus helicase in recognizing its substrates
Protein Cell, 7, 2016
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4LXL
 | | Crystal structure of JMJD2B complexed with pyridine-2,4-dicarboxylic acid and H3K9me3 | | 分子名称: | H3 peptide, Lysine-specific demethylase 4B, NICKEL (II) ION, ... | | 著者 | Wang, W.-C, Chu, C.-H, Chen, C.-C. | | 登録日 | 2013-07-30 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Crystal structure of JMJD2B complexed with pyridine-2,4-dicarboxylic acid and H3K9me3
To be Published
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4M8V
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5GWY
 | | Structure of Main Protease from Human Coronavirus NL63: Insights for Wide Spectrum Anti-Coronavirus Drug Design | | 分子名称: | N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE, main protease | | 著者 | Wang, F, Chen, C, Tan, W, Yang, K, Yang, H. | | 登録日 | 2016-09-14 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.852 Å) | | 主引用文献 | Structure of Main Protease from Human Coronavirus NL63: Insights for Wide Spectrum Anti-Coronavirus Drug Design.
Sci Rep, 6, 2016
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2JXU
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4JC2
 | | Isolation, Cloning and Biophysical Analysis of a Novel Hexameric Green Fluorescent Protein from a Philippine Soft Coral | | 分子名称: | asFP504 | | 著者 | Huang, Y.C, Emralino, F.L, Liu, F.C, Saloma, C.P, Bascos, N.A, Chen, C.J. | | 登録日 | 2013-02-21 | | 公開日 | 2014-03-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Isolation, Cloning and Biophysical Analysis of a Novel Hexameric Green Fluorescent Protein from a Philippine Soft Coral
To be Published
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3RI1
 | | Crystal structure of the catalytic domain of FGFR2 kinase in complex with ARQ 069 | | 分子名称: | (6S)-6-phenyl-5,6-dihydrobenzo[h]quinazolin-2-amine, Fibroblast growth factor receptor 2, SULFATE ION | | 著者 | Eathiraj, S, Palma, R, Hirschi, M, Volckova, E, Nakuci, E, Castro, J, Chen, C.R, Chan, T.C, France, D.S, Ashwell, M.A. | | 登録日 | 2011-04-12 | | 公開日 | 2011-05-04 | | 最終更新日 | 2011-10-19 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A novel mode of protein kinase inhibition exploiting hydrophobic motifs of autoinhibited kinases: discovery of ATP-independent inhibitors of fibroblast growth factor receptor.
J.Biol.Chem., 286, 2011
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2JN0
 | | Solution NMR structure of the ygdR protein from Escherichia coli. Northeast Structural Genomics target ER382A. | | 分子名称: | Hypothetical lipoprotein ygdR | | 著者 | Rossi, P, Chen, C.X, Jiang, M, Cunningham, K, Ma, L, Xiao, R, Liu, J.C, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2006-12-15 | | 公開日 | 2007-05-01 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of the ygdR protein from Escherichia coli. Northeast Structural Genomics target ER382A.
To be Published
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4L95
 | | Crystal structure of gamma glutamyl hydrolase (H218N) from zebrafish | | 分子名称: | GLYCEROL, Gamma-glutamyl hydrolase | | 著者 | Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. | | 登録日 | 2013-06-18 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase
J.Med.Chem., 56, 2013
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4EM1
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4L7Q
 | | Crystal structure of gamma glutamyl hydrolase (wild-type) from zebrafish | | 分子名称: | GLYCEROL, Gamma-glutamyl hydrolase | | 著者 | Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. | | 登録日 | 2013-06-14 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase
J.Med.Chem., 56, 2013
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2KXT
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4EJW
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6AB5
 | | Cryo-EM structure of T=1 Penaeus vannamei nodavirus | | 分子名称: | Capsid protein | | 著者 | Chen, N.C, Miyazaki, N, Yoshimura, M, Guan, H.H, Lin, C.C, Iwasaki, K, Chen, C.J. | | 登録日 | 2018-07-20 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism.
Commun Biol, 2, 2019
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4EJV
 | | Staphylococcus epidermidis TcaR in complex with chloramphenicol | | 分子名称: | 2,2-dichloro-N-[(1S,2S)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide, Transcriptional regulator TcaR | | 著者 | Chang, Y.M, Chen, C.K.M, Wang, A.H.J. | | 登録日 | 2012-04-07 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural analysis of the antibiotic recognition mechanism of MarR family proteins
Acta Crystallogr.,Sect.D, 2013
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3GCX
 | | PCSK9:EGFA (pH 7.4) | | 分子名称: | CALCIUM ION, Low-density lipoprotein receptor, Proprotein convertase subtilisin/kexin type 9 | | 著者 | McNutt, M.C, Kwon, H.J, Chen, C, Chen, J.R, Horton, J.D, Lagace, T.A. | | 登録日 | 2009-02-22 | | 公開日 | 2009-03-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Antagonism of Secreted PCSK9 Increases Low Density Lipoprotein Receptor Expression in HepG2 Cells.
J.Biol.Chem., 284, 2009
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4M4C
 | | Crystal structure of Rhodostomin ARGDP mutant | | 分子名称: | SULFATE ION, Zinc metalloproteinase/disintegrin | | 著者 | Chang, Y.T, Jeng, W.Y, Shiu, J.H, Chen, C.Y, Chuang, W.J. | | 登録日 | 2013-08-07 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Effect of C-terminal proline residue adjacent to the RGD motif in rhodostomin on its activity and structure
To be Published
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4QT5
 | | Crystal Structure of 3BD10: A Monoclonal Antibody against the TSH Receptor | | 分子名称: | 3BD10 mouse monoclonal antibody, heavy chain, light chain | | 著者 | Hubbard, P.A, Chen, C.R, McLachlan, S.M, Rapoport, B, Murali, R. | | 登録日 | 2014-07-07 | | 公開日 | 2015-04-01 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of a TSH receptor monoclonal antibody: insight into Graves' disease pathogenesis.
Mol.Endocrinol., 29, 2015
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4LRH
 | | Crystal structure of human folate receptor alpha in complex with folic acid | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, Folate receptor alpha | | 著者 | Ke, J, Chen, C, Zhou, X.E, Yi, W, Brunzelle, J.S, Li, J, Young, E.-L, Xu, H.E, Melcher, K. | | 登録日 | 2013-07-19 | | 公開日 | 2013-07-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for molecular recognition of folic acid by folate receptors.
Nature, 500, 2013
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2JNY
 | | Solution NMR structure of protein Uncharacterized BCR, Northeast Structural Genomics Consortium target CgR1 | | 分子名称: | Uncharacterized BCR | | 著者 | Wu, Y, Liu, G, Zhang, Q, Chen, C, Nwosu, C, Cunningham, K, Ma, L, Xiao, R, Liu, J, Baran, M, Swapna, G, Acton, T, Rost, B, Montelione, G, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2007-02-14 | | 公開日 | 2007-04-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of protein Uncharacterized BCR, Northeast Structural Genomics Consortium target CgR1
To be Published
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2JOZ
 | | Solution NMR structure of protein yxeF, Northeast Structural Genomics Consortium target Sr500a | | 分子名称: | Hypothetical protein yxeF | | 著者 | Wu, Y, Liu, G, Zhang, Q, Bhatnagar, S, Chen, C, Nwosu, C, Xiao, R, Cunningham, K, Locke, J, Ma, L, Swapna, G, Baran, M, Acton, T, Montelione, G, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2007-04-10 | | 公開日 | 2007-05-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of protein yxeF , Northeast Structural Genomics Consortium target Sr500a
To be Published
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4EJU
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4MY2
 | | Crystal Structure of Norrin in fusion with Maltose Binding Protein | | 分子名称: | Maltose-binding periplasmic protein, Norrin fusion protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Ke, J, Jurecky, C, Chen, C, Gu, X, Parker, N, Williams, B.O, Melcher, K, Xu, H.E. | | 登録日 | 2013-09-27 | | 公開日 | 2013-11-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complex.
Genes Dev., 27, 2013
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4L8W
 | | Crystal structure of gamma glutamyl hydrolase (H218N) from zebrafish complex with MTX polyglutamate | | 分子名称: | D-GLUTAMIC ACID, Gamma-glutamyl hydrolase, METHOTREXATE | | 著者 | Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. | | 登録日 | 2013-06-18 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase
J.Med.Chem., 56, 2013
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4L8Y
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