1JO5
 
 | | Rhodobacter sphaeroides Light Harvesting 1 beta Subunit in Detergent Micelles | | Descriptor: | LIGHT-HARVESTING PROTEIN B-875 | | Authors: | Sorgen, P.L, Cahill, S.M, Krueger-Koplin, R.D, Krueger-Koplin, S.T, Schenck, C.G, Girvin, M.E. | | Deposit date: | 2001-07-26 | | Release date: | 2002-02-27 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of the Rhodobacter sphaeroides light-harvesting 1 beta subunit in detergent micelles.
Biochemistry, 41, 2002
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5MFO
 | | Designed armadillo repeat protein YIIIM3AIII | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, YIIIM3AIII | | Authors: | Hansen, S, Ernst, P, Reichen, C, Ewald, C, Mittl, P, Plueckthun, A. | | Deposit date: | 2016-11-18 | | Release date: | 2017-09-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Curvature of designed armadillo repeat proteins allows modular peptide binding.
J. Struct. Biol., 201, 2018
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4PLQ
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3TVD
 | | Crystal Structure of Mouse RhoA-GTP complex | | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA | | Authors: | Swaminathan, K, Pal, K, Jobichen, C. | | Deposit date: | 2011-09-20 | | Release date: | 2012-10-10 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.989 Å) | | Cite: | Crystal structure of mouse RhoA:GTPgammaS complex in a centered lattice.
J.Struct.Funct.Genom., 13, 2012
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4JV4
 | | Crystal Structure of RIalpha(91-379) bound to HE33, a N6 di-propyl substituted cAMP analog | | Descriptor: | (2R,4aR,6R,7R,7aS)-6-[6-(dipropylamino)-9H-purin-9-yl]tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide, cAMP-dependent protein kinase type I-alpha regulatory subunit | | Authors: | Brown, S.H.J, Cheng, C.Y, Saldanha, A.S, Wu, J, Cottam, H, Sankaran, B, Taylor, S.S. | | Deposit date: | 2013-03-25 | | Release date: | 2013-09-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.952 Å) | | Cite: | Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs.
Acs Chem.Biol., 8, 2013
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2JG7
 | | Crystal structure of Seabream Antiquitin and Elucidation of its substrate specificity | | Descriptor: | ANTIQUITIN, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Tang, W.K, Wong, K.B, Cha, S.S, Lee, H.S, Cheng, C.H.K, Fong, W.P. | | Deposit date: | 2007-02-09 | | Release date: | 2008-05-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.83 Å) | | Cite: | The Crystal Structure of Seabream Antiquitin Reveals the Structural Basis of its Substrate Specificity.
FEBS Lett., 582, 2008
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5BN4
 | | Structure of a unique ATP synthase NeqA-NeqB in complex with ANP from Nanoarcheaum equitans | | Descriptor: | MAGNESIUM ION, NEQ263, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | | Deposit date: | 2015-05-25 | | Release date: | 2015-09-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.699 Å) | | Cite: | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans
J.Biol.Chem., 290, 2015
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5BN3
 | | Structure of a unique ATP synthase NeqA-NeqB in complex with ADP from Nanoarcheaum equitans | | Descriptor: | 1,4-DIETHYLENE DIOXIDE, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | | Authors: | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | | Deposit date: | 2015-05-25 | | Release date: | 2015-09-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans
J.Biol.Chem., 290, 2015
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5BO5
 | | Structure of a unique ATP synthase subunit NeqB from Nanoarcheaum equitans | | Descriptor: | MAGNESIUM ION, NEQ263, SULFATE ION | | Authors: | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | | Deposit date: | 2015-05-27 | | Release date: | 2015-09-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.808 Å) | | Cite: | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans
J.Biol.Chem., 290, 2015
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7OS9
 | | Crystal Structure of Domain Swapped Trp Repressor V58I Variant with purification tag | | Descriptor: | IMIDAZOLE, Trp operon repressor | | Authors: | Sprenger, J, Lawson, C.L, Lo Leggio, L, Von Wachenfeldt, C, Carey, J. | | Deposit date: | 2021-06-08 | | Release date: | 2021-07-14 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal structures of Val58Ile tryptophan repressor in a domain-swapped array in the presence and absence of L-tryptophan.
Acta Crystallogr.,Sect.F, 77, 2021
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5MFE
 | | Designed armadillo repeat protein YIIIM5AII in complex with (RR)4 peptide | | Descriptor: | (RR)4, 1,2-ETHANEDIOL, CALCIUM ION, ... | | Authors: | Hansen, S, Ernst, P, Reichen, C, Ewald, C, Mittl, P, Plueckthun, A. | | Deposit date: | 2016-11-18 | | Release date: | 2017-09-13 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Curvature of designed armadillo repeat proteins allows modular peptide binding.
J. Struct. Biol., 201, 2018
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5BN5
 | | Structural basis for a unique ATP synthase core complex from Nanoarcheaum equitans | | Descriptor: | NEQ263, SULFATE ION, V-type ATP synthase alpha chain | | Authors: | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | | Deposit date: | 2015-05-25 | | Release date: | 2015-09-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.997 Å) | | Cite: | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans
J.Biol.Chem., 290, 2015
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2L95
 | | Solution Structure of Cytotoxic T-Lymphocyte Antigent-2(Ctla protein), Crammer at pH 6.0 | | Descriptor: | Crammer | | Authors: | Tseng, T.S, Cheng, C.S, Liu, Y.N, Lyu, P.C. | | Deposit date: | 2011-01-31 | | Release date: | 2011-12-21 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | A molten globule-to-ordered structure transition of Drosophila melanogaster crammer is required for its ability to inhibit cathepsin.
Biochem.J., 442, 2012
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2HY6
 | | A seven-helix coiled coil | | Descriptor: | General control protein GCN4, HEXANE-1,6-DIOL | | Authors: | Liu, J, Zheng, Q, Deng, Y, Cheng, C.S, Kallenbach, N.R, Lu, M. | | Deposit date: | 2006-08-04 | | Release date: | 2006-10-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | A seven-helix coiled coil.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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5AEI
 | | Designed Armadillo repeat protein YIIIM5AII in complex with peptide (KR)5 | | Descriptor: | ACETATE ION, CALCIUM ION, DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII, ... | | Authors: | Hansen, S, Tremmel, D, Madhurantakam, C, Reichen, C, Mittl, P, Plueckthun, A. | | Deposit date: | 2015-08-31 | | Release date: | 2016-03-30 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Structure and Energetic Contributions of a Designed Modular Peptide-Binding Protein with Picomolar Affinity.
J.Am.Chem.Soc., 138, 2016
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7P3I
 | | Crystal structure of human CD40/TNFRSF5 in complex with the anti-CD40 DARPin protein | | Descriptor: | Darpin, SODIUM ION, Tumor necrosis factor receptor superfamily member 5 | | Authors: | Malvezzi, F, Mangold, S, Hospodarsch, T, Reichen, C, Iss, C, Lammens, A, Krapp, S, Domke, C. | | Deposit date: | 2021-07-07 | | Release date: | 2022-04-06 | | Last modified: | 2022-05-11 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | A Multispecific Anti-CD40 DARPin Construct Induces Tumor-Selective CD40 Activation and Tumor Regression.
Cancer Immunol Res, 10, 2022
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2GCX
 | | Solution Structure of Ferrous Iron Transport Protein A (FeoA) of Klebsiella pneumoniae | | Descriptor: | Ferrous iron transport protein A | | Authors: | Hung, K.-W, Cheng, C.-C, Yu, T.-H, Wang, S.-H, Chang, C.-F, Tsai, S.-F, Huang, T.-H. | | Deposit date: | 2006-03-14 | | Release date: | 2007-03-20 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Ferrous Iron Transport Protein A (FeoA) of Klebsiella pneumoniae
To be Published
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2HQE
 | | Crystal structure of human P100 Tudor domain: Large fragment | | Descriptor: | P100 Co-activator tudor domain | | Authors: | Shah, N, Zhao, M, Cheng, C, Xu, H, Yang, J, Silvennoinen, O, Liu, Z.J, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | | Deposit date: | 2006-07-18 | | Release date: | 2007-07-03 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of a large fragment of the Human P100 Tudor Domain
To be Published
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2DUW
 | | Solution structure of putative CoA-binding protein of Klebsiella pneumoniae | | Descriptor: | putative CoA-binding protein | | Authors: | Hung, K.W, Lin, Y.C, Cheng, C.C, Chang, C.F, Tsai, S.F, Huang, T.H. | | Deposit date: | 2006-07-27 | | Release date: | 2007-08-14 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of putative CoA-binding protein of Klebsiella pneumoniae
To be Published
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4R1Y
 | | Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitor | | Descriptor: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 3-(diethylamino)propyl (3-{[5-(3,4-dimethoxyphenyl)-2-oxo-2H-1,3,4-thiadiazin-3(6H)-yl]methyl}phenyl)carbamate, Hepatocyte growth factor receptor | | Authors: | Blaukat, A, Bladt, F, Friese-Hamim, M, Knuehl, C, Fittschen, C, Graedler, U, Meyring, M, Dorsch, D, Stieber, F, Schadt, O. | | Deposit date: | 2014-08-08 | | Release date: | 2015-03-18 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
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4R1V
 | | Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors | | Descriptor: | 3-[1-(3-{5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl}benzyl)-6-oxo-1,6-dihydropyridazin-3-yl]benzonitrile, GAMMA-BUTYROLACTONE, Hepatocyte growth factor receptor | | Authors: | Blaukat, A, Bladt, F, Friese-Hamim, M, Knuehl, C, Fittschen, C, Graedler, U, Meyring, M, Dorsch, D, Stieber, F, Schadt, O. | | Deposit date: | 2014-08-07 | | Release date: | 2015-03-18 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
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5OQV
 | | Near-atomic resolution fibril structure of complete amyloid-beta(1-42) by cryo-EM | | Descriptor: | Amyloid beta A4 protein | | Authors: | Gremer, L, Schoelzel, D, Schenk, C, Reinartz, E, Labahn, J, Ravelli, R, Tusche, M, Lopez-Iglesias, C, Hoyer, W, Heise, H, Willbold, D, Schroeder, G.F. | | Deposit date: | 2017-08-14 | | Release date: | 2017-09-13 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Fibril structure of amyloid-beta (1-42) by cryo-electron microscopy.
Science, 358, 2017
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2WRY
 | | Crystal structure of chicken cytokine interleukin 1 beta | | Descriptor: | INTERLEUKIN-1BETA | | Authors: | Lu, W.S, Cheng, C.S, Lyu, P.C, Lee, L.H, Wang, W.C, Yin, H.S. | | Deposit date: | 2009-09-03 | | Release date: | 2010-09-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Structural and Functional Comparison of Cytokine Interleukin-1 Beta from Chicken and Human.
Mol.Immunol., 48, 2011
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4JVA
 | | Crystal Structure of RIIbeta(108-402) bound to HE33, a N6 di-propyl substituted cAMP analog | | Descriptor: | (2R,4aR,6R,7R,7aS)-6-[6-(dipropylamino)-9H-purin-9-yl]tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide, cAMP-dependent protein kinase type II-beta regulatory subunit | | Authors: | Brown, S.H.J, Cheng, C.Y, Saldanha, A.S, Wu, J, Cottam, H, Sankaran, B, Taylor, S.S. | | Deposit date: | 2013-03-25 | | Release date: | 2013-09-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs.
Acs Chem.Biol., 8, 2013
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2VT2
 | | Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex | | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, REDOX-SENSING TRANSCRIPTIONAL REPRESSOR REX | | Authors: | Wang, E, Bauer, M.C, Rogstam, A, Linse, S, Logan, D.T, von Wachenfeldt, C. | | Deposit date: | 2008-05-08 | | Release date: | 2008-09-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex.
Mol. Microbiol., 69, 2008
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