5OA1
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![BU of 5oa1 by Molmil](/molmil-images/mine/5oa1) | RNA polymerase I pre-initiation complex | 分子名称: | ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ... | 著者 | Sadian, Y, Tafur, L, Kosinski, J, Jakobi, A.J, Muller, C.W. | 登録日 | 2017-06-20 | 公開日 | 2017-07-26 | 最終更新日 | 2018-10-24 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural insights into transcription initiation by yeast RNA polymerase I. EMBO J., 36, 2017
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1Z9W
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![BU of 1z9w by Molmil](/molmil-images/mine/1z9w) | Tetrameric structure of apo-7,8-Dihydroneopterin Aldolase from Mycobacterium tuberculosis | 分子名称: | Dihydroneopterin aldolase | 著者 | Goulding, C.W, Apostol, M.I, Sawaya, M.R, Philips, M, Parseghian, A, Eisenberg, D, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | 登録日 | 2005-04-05 | 公開日 | 2005-04-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme. J.Mol.Biol., 349, 2005
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3KCW
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![BU of 3kcw by Molmil](/molmil-images/mine/3kcw) | Crystal structure of Ganoderma fungal immunomodulatory protein, GMI | 分子名称: | immunomodulatory protein | 著者 | Hsu, M.F, Wang, A.H.J, Yang, C.S, Huang, C.T, Hseu, R.S, Lin, C.W, Wu, M.Y, Huang, C.S, Fu, H.Y. | 登録日 | 2009-10-22 | 公開日 | 2010-11-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Single cysteine replacement at Leu6 increase the potent and thermostability in Ganoderma fungal immunomodulatory proteins To be Published
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5DD6
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![BU of 5dd6 by Molmil](/molmil-images/mine/5dd6) | |
5DD3
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![BU of 5dd3 by Molmil](/molmil-images/mine/5dd3) | |
3KX5
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![BU of 3kx5 by Molmil](/molmil-images/mine/3kx5) | Crystal structure of Bacillus megaterium BM3 heme domain mutant F261E | 分子名称: | Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Girvan, H.M, Levy, C.W, Leys, D, Munro, A.W. | 登録日 | 2009-12-02 | 公開日 | 2010-05-19 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.686 Å) | 主引用文献 | Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3. Biochem.J., 427, 2010
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5OP9
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![BU of 5op9 by Molmil](/molmil-images/mine/5op9) | The crystal structure of P450 CYP121 in complex with lead compound 7e | 分子名称: | 4-(imidazol-1-ylmethyl)-3-(4-methoxyphenyl)-1-phenyl-pyrazole, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Levy, C.W. | 登録日 | 2017-08-09 | 公開日 | 2018-03-28 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.455 Å) | 主引用文献 | Novel Aryl Substituted Pyrazoles as Small Molecule Inhibitors of Cytochrome P450 CYP121A1: Synthesis and Antimycobacterial Evaluation. J. Med. Chem., 60, 2017
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5OMU
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![BU of 5omu by Molmil](/molmil-images/mine/5omu) | Crystal structure of Amycolatopsis cytochrome P450 GcoA in complex with syringol | 分子名称: | 2,6-dimethoxyphenol, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Mallinson, S.J.B, Johnson, C.W, Neidle, E.L, Beckham, G.T, McGeehan, J.E. | 登録日 | 2017-08-01 | 公開日 | 2018-07-04 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion. Nat Commun, 9, 2018
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5OPA
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![BU of 5opa by Molmil](/molmil-images/mine/5opa) | The crystal structure of P450 CYP121 in complex with lead compound 7b | 分子名称: | 3-(4-fluorophenyl)-4-(imidazol-1-ylmethyl)-1-phenyl-pyrazole, DI(HYDROXYETHYL)ETHER, Mycocyclosin synthase, ... | 著者 | Levy, C.W. | 登録日 | 2017-08-09 | 公開日 | 2018-03-28 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.345 Å) | 主引用文献 | Novel Aryl Substituted Pyrazoles as Small Molecule Inhibitors of Cytochrome P450 CYP121A1: Synthesis and Antimycobacterial Evaluation. J. Med. Chem., 60, 2017
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3KVF
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5DD5
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3KX3
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![BU of 3kx3 by Molmil](/molmil-images/mine/3kx3) | Crystal structure of Bacillus megaterium BM3 heme domain mutant L86E | 分子名称: | Bifunctional P-450/NADPH-P450 reductase, N-PALMITOYLGLYCINE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Girvan, H.M, Levy, C.W, Leys, D, Munro, A.W. | 登録日 | 2009-12-02 | 公開日 | 2010-05-19 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | 主引用文献 | Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3. Biochem.J., 427, 2010
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3KJ6
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![BU of 3kj6 by Molmil](/molmil-images/mine/3kj6) | Crystal structure of a Methylated beta2 Adrenergic Receptor-Fab complex | 分子名称: | Beta-2 adrenergic receptor, Fab heavy chain, Fab light chain, ... | 著者 | Bokoch, M.P, Zou, Y, Rasmussen, S.G.F, Liu, C.W, Nygaard, R, Rosenbaum, D.M, Fung, J.J, Choi, H.-J, Thian, F.S, Kobilka, T.S, Puglisi, J.D, Weis, W.I, Pardo, L, Prosser, S, Mueller, L, Kobilka, B.K. | 登録日 | 2009-11-02 | 公開日 | 2010-02-16 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor. Nature, 463, 2010
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2AB5
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![BU of 2ab5 by Molmil](/molmil-images/mine/2ab5) | bI3 LAGLIDADG Maturase | 分子名称: | SULFATE ION, mRNA maturase | 著者 | Longo, A, Leonard, C.W, Bassi, G.S, Berndt, D, Krahn, J.M, Hall, T.M, Weeks, K.M. | 登録日 | 2005-07-14 | 公開日 | 2005-08-30 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Evolution from DNA to RNA recognition by the bI3 LAGLIDADG maturase Nat.Struct.Mol.Biol., 12, 2005
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1XE0
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![BU of 1xe0 by Molmil](/molmil-images/mine/1xe0) | The structure and function of Xenopus NO38-core, a histone binding chaperone in the nucleolus | 分子名称: | Nucleophosmin | 著者 | Namboodiri, V.M, Akey, I.V, Schmidt-Zachmann, M.S, Head, J.F, Akey, C.W. | 登録日 | 2004-09-08 | 公開日 | 2004-12-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Structure and Function of Xenopus NO38-Core, a Histone Chaperone in the Nucleolus. Structure, 12, 2004
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1XBO
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![BU of 1xbo by Molmil](/molmil-images/mine/1xbo) | PTP1B complexed with Isoxazole Carboxylic Acid | 分子名称: | 5-(3-{3-[3-HYDROXY-2-(METHOXYCARBONYL)PHENOXY]PROPENYL}PHENYL)-4-(HYDROXYMETHYL)ISOXAZOLE-3-CARBOXYLIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 | 著者 | Zhao, H, Liu, G, Xin, Z, Serby, M, Pei, Z, Szczepankiewicz, B.G, Hajduk, P.J, Abad-Zapatero, C, Hutchins, C.W, Lubben, T.H, Ballaron, S.J, Hassach, D.L, Kaszubska, W, Rondinone, C.M, Trevillyan, J.M, Jirousek, M.R. | 登録日 | 2004-08-31 | 公開日 | 2004-10-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors. Bioorg.Med.Chem.Lett., 14, 2004
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1XB9
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![BU of 1xb9 by Molmil](/molmil-images/mine/1xb9) | The structure and function of Xenopus NO38-core, a histone chaperone in the nucleolus | 分子名称: | Nucleophosmin | 著者 | Namboodiri, V.M, Akey, I.V, Schmidt-Zachmann, M.S, Head, J.F, Akey, C.W. | 登録日 | 2004-08-30 | 公開日 | 2004-12-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Structure and Function of Xenopus NO38-Core, a Histone Chaperone in the Nucleolus. Structure, 12, 2004
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8EW6
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![BU of 8ew6 by Molmil](/molmil-images/mine/8ew6) | Anti-human CD8 VHH complex with CD8 alpha | 分子名称: | Anti-CD8 alpha VHH, T-cell surface glycoprotein CD8 alpha chain | 著者 | Kiefer, J.R, Williams, S, Davies, C.W, Koerber, J.T, Sriraman, S.K, Yin, Y.P. | 登録日 | 2022-10-21 | 公開日 | 2022-11-23 | 最終更新日 | 2023-02-01 | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | 主引用文献 | Development of an 18 F-labeled anti-human CD8 VHH for same-day immunoPET imaging. Eur J Nucl Med Mol Imaging, 50, 2023
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6A7J
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![BU of 6a7j by Molmil](/molmil-images/mine/6a7j) | Testerone bound CYP154C4 from Streptomyces sp. ATCC 11861 | 分子名称: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE | 著者 | Lee, C.W, Lee, J.H. | 登録日 | 2018-07-03 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Characterization of two steroid hydroxylases from different Streptomyces spp. and their ligand-bound and -unbound crystal structures. Febs J., 286, 2019
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6A2E
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![BU of 6a2e by Molmil](/molmil-images/mine/6a2e) | Apo structure of the Kdo hydroxylase KdoO, a non-heme Fe(II) alphaketoglutarate dependent dioxygenase | 分子名称: | ACETATE ION, Kdo hydroxylase, KdoO, ... | 著者 | Chung, H.S, Pemble, C.W, Joo, S.H. | 登録日 | 2018-06-11 | 公開日 | 2018-09-05 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.939 Å) | 主引用文献 | Biochemical and Structural Insights into an Fe(II)/ alpha-Ketoglutarate/O2-Dependent Dioxygenase, Kdo 3-Hydroxylase (KdoO). J. Mol. Biol., 430, 2018
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6A4D
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6A4E
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8ELZ
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![BU of 8elz by Molmil](/molmil-images/mine/8elz) | HRAS R97M Crystal Form 1 | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GTPase HRas, ... | 著者 | Johnson, C.W, Mattos, C. | 登録日 | 2022-09-26 | 公開日 | 2023-09-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.961 Å) | 主引用文献 | Allosteric site variants affect GTP hydrolysis on Ras. Protein Sci., 32, 2023
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8ELS
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![BU of 8els by Molmil](/molmil-images/mine/8els) | HRAS R97A Crystal Form 1 R-state | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Davis, D, Johnson, C.W, Mattos, C. | 登録日 | 2022-09-26 | 公開日 | 2023-09-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.267 Å) | 主引用文献 | Allosteric site variants affect GTP hydrolysis on Ras. Protein Sci., 32, 2023
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6A7I
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![BU of 6a7i by Molmil](/molmil-images/mine/6a7i) | CYP154C4 from Streptomyces sp. W2061 | 分子名称: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Lee, C.W, Lee, J.H. | 登録日 | 2018-07-03 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Characterization of two steroid hydroxylases from different Streptomyces spp. and their ligand-bound and -unbound crystal structures. Febs J., 286, 2019
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