5OA1
 
 | | RNA polymerase I pre-initiation complex | | 分子名称: | ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ... | | 著者 | Sadian, Y, Tafur, L, Kosinski, J, Jakobi, A.J, Muller, C.W. | | 登録日 | 2017-06-20 | | 公開日 | 2017-07-26 | | 最終更新日 | 2018-10-24 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural insights into transcription initiation by yeast RNA polymerase I.
EMBO J., 36, 2017
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1Z9W
 | | Tetrameric structure of apo-7,8-Dihydroneopterin Aldolase from Mycobacterium tuberculosis | | 分子名称: | Dihydroneopterin aldolase | | 著者 | Goulding, C.W, Apostol, M.I, Sawaya, M.R, Philips, M, Parseghian, A, Eisenberg, D, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | | 登録日 | 2005-04-05 | | 公開日 | 2005-04-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
J.Mol.Biol., 349, 2005
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3KCW
 | | Crystal structure of Ganoderma fungal immunomodulatory protein, GMI | | 分子名称: | immunomodulatory protein | | 著者 | Hsu, M.F, Wang, A.H.J, Yang, C.S, Huang, C.T, Hseu, R.S, Lin, C.W, Wu, M.Y, Huang, C.S, Fu, H.Y. | | 登録日 | 2009-10-22 | | 公開日 | 2010-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Single cysteine replacement at Leu6 increase the potent and thermostability in Ganoderma fungal immunomodulatory proteins
To be Published
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5DD6
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5DD3
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3KX5
 | | Crystal structure of Bacillus megaterium BM3 heme domain mutant F261E | | 分子名称: | Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | 著者 | Girvan, H.M, Levy, C.W, Leys, D, Munro, A.W. | | 登録日 | 2009-12-02 | | 公開日 | 2010-05-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.686 Å) | | 主引用文献 | Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3.
Biochem.J., 427, 2010
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5OP9
 | | The crystal structure of P450 CYP121 in complex with lead compound 7e | | 分子名称: | 4-(imidazol-1-ylmethyl)-3-(4-methoxyphenyl)-1-phenyl-pyrazole, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Levy, C.W. | | 登録日 | 2017-08-09 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.455 Å) | | 主引用文献 | Novel Aryl Substituted Pyrazoles as Small Molecule Inhibitors of Cytochrome P450 CYP121A1: Synthesis and Antimycobacterial Evaluation.
J. Med. Chem., 60, 2017
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5OMU
 | | Crystal structure of Amycolatopsis cytochrome P450 GcoA in complex with syringol | | 分子名称: | 2,6-dimethoxyphenol, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Mallinson, S.J.B, Johnson, C.W, Neidle, E.L, Beckham, G.T, McGeehan, J.E. | | 登録日 | 2017-08-01 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion.
Nat Commun, 9, 2018
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5OPA
 | | The crystal structure of P450 CYP121 in complex with lead compound 7b | | 分子名称: | 3-(4-fluorophenyl)-4-(imidazol-1-ylmethyl)-1-phenyl-pyrazole, DI(HYDROXYETHYL)ETHER, Mycocyclosin synthase, ... | | 著者 | Levy, C.W. | | 登録日 | 2017-08-09 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.345 Å) | | 主引用文献 | Novel Aryl Substituted Pyrazoles as Small Molecule Inhibitors of Cytochrome P450 CYP121A1: Synthesis and Antimycobacterial Evaluation.
J. Med. Chem., 60, 2017
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3KVF
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5DD5
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3KX3
 | | Crystal structure of Bacillus megaterium BM3 heme domain mutant L86E | | 分子名称: | Bifunctional P-450/NADPH-P450 reductase, N-PALMITOYLGLYCINE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Girvan, H.M, Levy, C.W, Leys, D, Munro, A.W. | | 登録日 | 2009-12-02 | | 公開日 | 2010-05-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | | 主引用文献 | Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3.
Biochem.J., 427, 2010
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3KJ6
 | | Crystal structure of a Methylated beta2 Adrenergic Receptor-Fab complex | | 分子名称: | Beta-2 adrenergic receptor, Fab heavy chain, Fab light chain, ... | | 著者 | Bokoch, M.P, Zou, Y, Rasmussen, S.G.F, Liu, C.W, Nygaard, R, Rosenbaum, D.M, Fung, J.J, Choi, H.-J, Thian, F.S, Kobilka, T.S, Puglisi, J.D, Weis, W.I, Pardo, L, Prosser, S, Mueller, L, Kobilka, B.K. | | 登録日 | 2009-11-02 | | 公開日 | 2010-02-16 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.
Nature, 463, 2010
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2AB5
 | | bI3 LAGLIDADG Maturase | | 分子名称: | SULFATE ION, mRNA maturase | | 著者 | Longo, A, Leonard, C.W, Bassi, G.S, Berndt, D, Krahn, J.M, Hall, T.M, Weeks, K.M. | | 登録日 | 2005-07-14 | | 公開日 | 2005-08-30 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Evolution from DNA to RNA recognition by the bI3 LAGLIDADG maturase
Nat.Struct.Mol.Biol., 12, 2005
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1XE0
 | | The structure and function of Xenopus NO38-core, a histone binding chaperone in the nucleolus | | 分子名称: | Nucleophosmin | | 著者 | Namboodiri, V.M, Akey, I.V, Schmidt-Zachmann, M.S, Head, J.F, Akey, C.W. | | 登録日 | 2004-09-08 | | 公開日 | 2004-12-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Structure and Function of Xenopus NO38-Core, a Histone Chaperone in the Nucleolus.
Structure, 12, 2004
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1XBO
 | | PTP1B complexed with Isoxazole Carboxylic Acid | | 分子名称: | 5-(3-{3-[3-HYDROXY-2-(METHOXYCARBONYL)PHENOXY]PROPENYL}PHENYL)-4-(HYDROXYMETHYL)ISOXAZOLE-3-CARBOXYLIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 | | 著者 | Zhao, H, Liu, G, Xin, Z, Serby, M, Pei, Z, Szczepankiewicz, B.G, Hajduk, P.J, Abad-Zapatero, C, Hutchins, C.W, Lubben, T.H, Ballaron, S.J, Hassach, D.L, Kaszubska, W, Rondinone, C.M, Trevillyan, J.M, Jirousek, M.R. | | 登録日 | 2004-08-31 | | 公開日 | 2004-10-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
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1XB9
 | | The structure and function of Xenopus NO38-core, a histone chaperone in the nucleolus | | 分子名称: | Nucleophosmin | | 著者 | Namboodiri, V.M, Akey, I.V, Schmidt-Zachmann, M.S, Head, J.F, Akey, C.W. | | 登録日 | 2004-08-30 | | 公開日 | 2004-12-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Structure and Function of Xenopus NO38-Core, a Histone Chaperone in the Nucleolus.
Structure, 12, 2004
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8EW6
 | | Anti-human CD8 VHH complex with CD8 alpha | | 分子名称: | Anti-CD8 alpha VHH, T-cell surface glycoprotein CD8 alpha chain | | 著者 | Kiefer, J.R, Williams, S, Davies, C.W, Koerber, J.T, Sriraman, S.K, Yin, Y.P. | | 登録日 | 2022-10-21 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-02-01 | | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | | 主引用文献 | Development of an 18 F-labeled anti-human CD8 VHH for same-day immunoPET imaging.
Eur J Nucl Med Mol Imaging, 50, 2023
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6A7J
 | | Testerone bound CYP154C4 from Streptomyces sp. ATCC 11861 | | 分子名称: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE | | 著者 | Lee, C.W, Lee, J.H. | | 登録日 | 2018-07-03 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Characterization of two steroid hydroxylases from different Streptomyces spp. and their ligand-bound and -unbound crystal structures.
Febs J., 286, 2019
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6A2E
 | | Apo structure of the Kdo hydroxylase KdoO, a non-heme Fe(II) alphaketoglutarate dependent dioxygenase | | 分子名称: | ACETATE ION, Kdo hydroxylase, KdoO, ... | | 著者 | Chung, H.S, Pemble, C.W, Joo, S.H. | | 登録日 | 2018-06-11 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.939 Å) | | 主引用文献 | Biochemical and Structural Insights into an Fe(II)/ alpha-Ketoglutarate/O2-Dependent Dioxygenase, Kdo 3-Hydroxylase (KdoO).
J. Mol. Biol., 430, 2018
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6A4D
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6A4E
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8ELZ
 | | HRAS R97M Crystal Form 1 | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GTPase HRas, ... | | 著者 | Johnson, C.W, Mattos, C. | | 登録日 | 2022-09-26 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.961 Å) | | 主引用文献 | Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
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8ELS
 | | HRAS R97A Crystal Form 1 R-state | | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | | 著者 | Davis, D, Johnson, C.W, Mattos, C. | | 登録日 | 2022-09-26 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.267 Å) | | 主引用文献 | Allosteric site variants affect GTP hydrolysis on Ras.
Protein Sci., 32, 2023
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6A7I
 | | CYP154C4 from Streptomyces sp. W2061 | | 分子名称: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Lee, C.W, Lee, J.H. | | 登録日 | 2018-07-03 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Characterization of two steroid hydroxylases from different Streptomyces spp. and their ligand-bound and -unbound crystal structures.
Febs J., 286, 2019
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