3KJ6

Crystal structure of a Methylated beta2 Adrenergic Receptor-Fab complex

Summary for 3KJ6

DescriptorBeta-2 adrenergic receptor, Fab light chain, Fab heavy chain, ... (4 entities in total)
Functional Keywordstransmembrane helices, cell membrane, disulfide bond, g-protein coupled receptor, glycoprotein, lipoprotein, membrane, palmitate, phosphoprotein, polymorphism, receptor, transducer, transmembrane, signaling protein
Biological sourceHomo sapiens (human)
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Cellular locationCell membrane ; Multi- pass membrane protein  P07550
Total number of polymer chains3
Total molecular weight88604.47
Authors
Primary citation
Bokoch, M.P.,Zou, Y.,Rasmussen, S.G.,Liu, C.W.,Nygaard, R.,Rosenbaum, D.M.,Fung, J.J.,Choi, H.J.,Thian, F.S.,Kobilka, T.S.,Puglisi, J.D.,Weis, W.I.,Pardo, L.,Prosser, R.S.,Mueller, L.,Kobilka, B.K.
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.
Nature, 463:108-112, 2010
PubMed: 20054398 (PDB entries with the same primary citation)
DOI: 10.1038/nature08650
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.268221.6%6.3%5.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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