1QBP
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1NND
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![BU of 1nnd by Molmil](/molmil-images/mine/1nnd) | Arginine 116 is Essential for Nucleic Acid Recognition by the Fingers Domain of Moloney Murine Leukemia Virus Reverse Transcriptase | Descriptor: | Reverse Transcriptase | Authors: | Crowther, R.L, Remeta, D.P, Minetti, C.A, Das, D, Montano, S.P, Georgiadis, M.M. | Deposit date: | 2003-01-13 | Release date: | 2004-01-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and energetic characterization of nucleic acid-binding to the fingers domain of Moloney murine leukemia virus reverse transcriptase Proteins, 57, 2004
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1NR7
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![BU of 1nr7 by Molmil](/molmil-images/mine/1nr7) | Crystal structure of apo bovine glutamate dehydrogenase | Descriptor: | Glutamate dehydrogenase 1 | Authors: | Banerjee, S, Schmidt, T, Fang, J, Stanley, C.A, Smith, T.J. | Deposit date: | 2003-01-23 | Release date: | 2003-05-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation Biochemistry, 42, 2003
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1Q1Z
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![BU of 1q1z by Molmil](/molmil-images/mine/1q1z) | Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of PAP | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, SODIUM ION, sulfotransferase family, ... | Authors: | Lee, K.A, Fuda, H, Lee, Y.C, Negishi, M, Strott, C.A, Pedersen, L.C. | Deposit date: | 2003-07-23 | Release date: | 2003-11-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone
and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical
SULT2A1 and the SULT2BG1 isoforms. J.Biol.Chem., 278, 2003
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1Q1Q
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![BU of 1q1q by Molmil](/molmil-images/mine/1q1q) | Crystal structure of human pregnenolone sulfotransferase (SULT2B1a) in the presence of PAP | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ADENOSINE-3'-5'-DIPHOSPHATE, SODIUM ION, ... | Authors: | Lee, K.A, Fuda, H, Lee, Y.C, Negishi, M, Strott, C.A, Pedersen, L.C. | Deposit date: | 2003-07-22 | Release date: | 2003-11-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone
and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical
SULT2A1 and the SULT2BG1 isoforms. J.Biol.Chem., 278, 2003
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1QX4
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![BU of 1qx4 by Molmil](/molmil-images/mine/1qx4) | Structrue of S127P mutant of cytochrome b5 reductase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase | Authors: | Bewley, M.C, Davis, C.A, Marohnic, C.C, Taormina, D, Barber, M.J. | Deposit date: | 2003-09-04 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure of the S127P mutant of cytochrome b5 reductase that causes methemoglobinemia shows the AMP moiety of the flavin occupying the substrate binding site Biochemistry, 42, 2003
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1QTF
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![BU of 1qtf by Molmil](/molmil-images/mine/1qtf) | CRYSTAL STRUCTURE OF EXFOLIATIVE TOXIN B | Descriptor: | EXFOLIATIVE TOXIN B | Authors: | Vath, G.M, Earhart, C.A, Monie, D.D, Schlievert, P.M, Ohlendorf, D.H. | Deposit date: | 1999-06-27 | Release date: | 1999-08-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure of exfoliative toxin B: a superantigen with enzymatic activity. Biochemistry, 38, 1999
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1MHE
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![BU of 1mhe by Molmil](/molmil-images/mine/1mhe) | THE HUMAN NON-CLASSICAL MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE HLA-E | Descriptor: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN HLA-E, PEPTIDE (VMAPRTVLL), ... | Authors: | O'Callaghan, C.A, Tormo, J, Willcox, B.E, Braud, V.B, Jakobsen, B.K, Stuart, D.I, Mcmichael, A.J, Bell, J.I, Jones, E.Y. | Deposit date: | 1998-08-24 | Release date: | 1999-03-23 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E. Mol.Cell, 1, 1998
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1MEY
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![BU of 1mey by Molmil](/molmil-images/mine/1mey) | CRYSTAL STRUCTURE OF A DESIGNED ZINC FINGER PROTEIN BOUND TO DNA | Descriptor: | CHLORIDE ION, CONSENSUS ZINC FINGER, DNA (5'-D(*AP*TP*GP*AP*GP*GP*CP*AP*GP*AP*AP*CP*T)-3'), ... | Authors: | Kim, C.A, Berg, J.M. | Deposit date: | 1996-09-27 | Release date: | 1997-03-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A 2.2 A Resolution Crystal Structure of a Designed Zinc Finger Protein Bound to DNA Nat.Struct.Biol., 3, 1996
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6M44
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![BU of 6m44 by Molmil](/molmil-images/mine/6m44) | 355 bp di-nucleosome harboring cohesive DNA termini (high cryoprotectant) | Descriptor: | CALCIUM ION, DNA (355-MER), Histone H2A type 1-B/E, ... | Authors: | Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. | Deposit date: | 2020-03-05 | Release date: | 2020-10-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.81 Å) | Cite: | Near-atomic resolution structures of interdigitated nucleosome fibres. Nat Commun, 11, 2020
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4D45
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![BU of 4d45 by Molmil](/molmil-images/mine/4d45) | Crystal structure of S. aureus FabI in complex with NADP and 5-bromo- 2-(4-chloro-2-hydroxyphenoxy)benzonitrile | Descriptor: | 5-bromo-2-(4-chloro-2-hydroxyphenoxy)benzonitrile, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... | Authors: | Tareilus, M, Schiebel, J, Chang, A, Tonge, P.J, Sotriffer, C.A, Kisker, C. | Deposit date: | 2014-10-26 | Release date: | 2015-03-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | An Ordered Water Channel in Staphylococcus Aureus Fabi: Unraveling the Mechanism of Substrate Recognition and Reduction. Biochemistry, 54, 2015
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6OOD
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![BU of 6ood by Molmil](/molmil-images/mine/6ood) | Structure of the pterocarpan synthase dirigent protein PsPTS1 | Descriptor: | pterocarpan synthase dirigent protein PsPTS1 | Authors: | Smith, C.A. | Deposit date: | 2019-04-23 | Release date: | 2020-04-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Pterocarpan synthase (PTS) structures suggest a common quinone methide-stabilizing function in dirigent proteins and proteins with dirigent-like domains. J.Biol.Chem., 295, 2020
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6OOU
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![BU of 6oou by Molmil](/molmil-images/mine/6oou) | Crystal structure of HIV-1 Protease NL4-3 L89V Mutant in complex with darunavir | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, NL4-3 PROTEASE, SULFATE ION | Authors: | Henes, M, Kosovrasti, K, Lockbaum, G.J, Leidner, F, Nachum, G.S, Nalivaika, E.A, Bolon, D.N.A, KurtYilmaz, N, Schiffer, C.A, Whitfield, T.W. | Deposit date: | 2019-04-23 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.127 Å) | Cite: | Molecular Determinants of Epistasis in HIV-1 Protease: Elucidating the Interdependence of L89V and L90M Mutations in Resistance. Biochemistry, 58, 2019
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6O4M
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![BU of 6o4m by Molmil](/molmil-images/mine/6o4m) | Racemic melittin | Descriptor: | D-Melittin, Melittin, SULFATE ION | Authors: | Kurgan, K.W, Bingman, C.A, Gellman, S.H, Forest, K.T. | Deposit date: | 2019-02-28 | Release date: | 2019-05-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Retention of Native Quaternary Structure in Racemic Melittin Crystals. J.Am.Chem.Soc., 141, 2019
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6M3V
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![BU of 6m3v by Molmil](/molmil-images/mine/6m3v) | 355 bp di-nucleosome harboring cohesive DNA termini | Descriptor: | CALCIUM ION, DNA (355-MER), Histone H2A type 1-B/E, ... | Authors: | Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. | Deposit date: | 2020-03-04 | Release date: | 2020-10-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (4.6 Å) | Cite: | Near-atomic resolution structures of interdigitated nucleosome fibres. Nat Commun, 11, 2020
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116D
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117D
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4D41
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![BU of 4d41 by Molmil](/molmil-images/mine/4d41) | Crystal structure of S. aureus FabI in complex with NADP and 5-hexyl- 2-(4-nitrophenoxy)phenol | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 5-HEXYL-2-(4-NITROPHENOXY)PHENOL, ... | Authors: | Schiebel, J, Chang, A, Tonge, P.J, Sotriffer, C.A, Kisker, C. | Deposit date: | 2014-10-26 | Release date: | 2015-03-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | An Ordered Water Channel in Staphylococcus Aureus Fabi: Unraveling the Mechanism of Substrate Recognition and Reduction. Biochemistry, 54, 2015
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3LEZ
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2FZD
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![BU of 2fzd by Molmil](/molmil-images/mine/2fzd) | Human aldose reductase complexed with tolrestat at 1.08 A resolution. | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TOLRESTAT, aldose reductase | Authors: | Steuber, H, Zentgraf, M, Gerlach, C, Sotriffer, C.A, Heine, A, Klebe, G. | Deposit date: | 2006-02-09 | Release date: | 2006-10-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Expect the Unexpected or Caveat for Drug Designers: Multiple Structure Determinations Using Aldose Reductase Crystals Treated under Varying Soaking and Co-crystallisation Conditions. J.Mol.Biol., 363, 2006
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6OPU
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![BU of 6opu by Molmil](/molmil-images/mine/6opu) | HIV-1 Protease NL4-3 K45I, M46I, V82F, I84V Mutant in complex with darunavir | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease NL4-3 | Authors: | Lockbaum, G.J, Henes, M, Kosovrasti, K, Leidner, F, Nachum, G.S, Nalivaika, E.A, Bolon, D.N.A, KurtYilmaz, N, Schiffer, C.A. | Deposit date: | 2019-04-25 | Release date: | 2019-09-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance. Acs Chem.Biol., 14, 2019
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6OPY
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![BU of 6opy by Molmil](/molmil-images/mine/6opy) | HIV-1 Protease NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, A71V, L76V, V82F, I84V Mutant in complex with darunavir | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease NL4-3 | Authors: | Lockbaum, G.J, Henes, M, Kosovrasti, K, Leidner, F, Nachum, G.S, Nalivaika, E.A, Bolon, D.N.A, KurtYilmaz, N, Schiffer, C.A. | Deposit date: | 2019-04-25 | Release date: | 2019-09-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance. Acs Chem.Biol., 14, 2019
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2FZ9
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![BU of 2fz9 by Molmil](/molmil-images/mine/2fz9) | Human Aldose Reductase complexed with inhibitor zopolrestat after six days soaking. | Descriptor: | 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, aldose reductase | Authors: | Steuber, H, Zentgraf, M, Gerlach, C, Sotriffer, C.A, Heine, A, Klebe, G. | Deposit date: | 2006-02-09 | Release date: | 2006-10-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Expect the Unexpected or Caveat for Drug Designers: Multiple Structure Determinations Using Aldose Reductase Crystals Treated under Varying Soaking and Co-crystallisation Conditions. J.Mol.Biol., 363, 2006
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2G09
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![BU of 2g09 by Molmil](/molmil-images/mine/2g09) | X-ray structure of mouse pyrimidine 5'-nucleotidase type 1, product complex | Descriptor: | Cytosolic 5'-nucleotidase III, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2006-02-11 | Release date: | 2006-04-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning. J.Biol.Chem., 281, 2006
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2MH2
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![BU of 2mh2 by Molmil](/molmil-images/mine/2mh2) | Structural insights into the DNA recognition and protein interaction domains reveal fundamental homologous DNA pairing properties of HOP2 | Descriptor: | Homologous-pairing protein 2 homolog | Authors: | Moktan, H, Guiraldelli, M.F, Eyter, C.A, Zhao, W, Camerini-Otero, R.D, Sung, P, Zhou, D.H, Pezza, R.J. | Deposit date: | 2013-11-13 | Release date: | 2014-04-16 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution Structure and DNA-binding Properties of the Winged Helix Domain of the Meiotic Recombination HOP2 Protein. J.Biol.Chem., 289, 2014
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