8PPQ
 
 | | Tick-borne encephalitis virus Kuutsalo-14 prM3E3 trimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, Protein prM | | 著者 | Anastasina, M, Domanska, A, Pulkkinen, L.I.A, Butcher, S.J. | | 登録日 | 2023-07-07 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | The structure of immature tick-borne encephalitis virus supports the collapse model of flavivirus maturation.
Sci Adv, 10, 2024
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6ZCK
 | | Coxsackievirus B4 in complex with capsid binder compound 48 | | 分子名称: | 4-[(6-propoxynaphthalen-2-yl)sulfonylamino]benzoic acid, Capsid protein VP1, Capsid protein VP2, ... | | 著者 | Flatt, J.W, Domanska, A, Butcher, S.J. | | 登録日 | 2020-06-11 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Identification of a conserved virion-stabilizing network inside the interprotomer pocket of enteroviruses.
Commun Biol, 4, 2021
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1HI8
 | | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 | | 分子名称: | MAGNESIUM ION, P2 PROTEIN | | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | | 登録日 | 2001-01-03 | | 公開日 | 2001-03-27 | | 最終更新日 | 2019-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
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1HHS
 | | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 | | 分子名称: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | | 登録日 | 2000-12-28 | | 公開日 | 2001-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
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1HHT
 | | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus template | | 分子名称: | DNA (5'-(*TP*TP*TP*CP*C)-3'), MANGANESE (II) ION, P2 PROTEIN | | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | | 登録日 | 2000-12-28 | | 公開日 | 2001-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
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1HI1
 | | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus bound NTP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, P2 PROTEIN | | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | | 登録日 | 2001-01-01 | | 公開日 | 2001-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
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7Z51
 | | Tick-borne encephalitis virus Kuutsalo-14 | | 分子名称: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | | 著者 | Pulkkinen, L.I.A, Barrass, S.V, Anastasina, M, Butcher, S.J. | | 登録日 | 2022-03-07 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular Organisation of Tick-Borne Encephalitis Virus.
Viruses, 14, 2022
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6RJF
 | | Echovirus 1 intact particle | | 分子名称: | PALMITIC ACID, VP1, VP2, ... | | 著者 | Domanska, A, Ruokolainen, V.P, Pelliccia, M, Laajala, M.A, Marjomaki, V.S, Butcher, S.J. | | 登録日 | 2019-04-26 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Extracellular Albumin and Endosomal Ions Prime Enterovirus Particles for Uncoating That Can Be Prevented by Fatty Acid Saturation.
J.Virol., 93, 2019
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8AXX
 | | Expanded Coxsackievirus A9 after treatment with endosomal ionic buffer | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | | 著者 | Domanska, A, Plavec, Z, Ruokolainen, V, Loflund, B, Marjomaki, V.S, Butcher, S.J. | | 登録日 | 2022-09-01 | | 公開日 | 2022-10-19 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release.
J.Virol., 96, 2022
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8AW6
 | | Expanded Coxsackievirus A9 after 0.01% faf-BSA treatment | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | | 著者 | Domanska, A, Plavec, Z, Ruokolainen, V, Loflund, B, Marjomaki, V.S, Butcher, S.J. | | 登録日 | 2022-08-29 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release.
J.Virol., 96, 2022
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8AT5
 | | native Coxsackievirus A9 | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Domanska, A, Plavec, Z, Ruokolainen, V, Marjomaki, V.S, Butcher, S.J. | | 登録日 | 2022-08-22 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release.
J.Virol., 96, 2022
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6ZCL
 | | Coxsackievirus B3 in complex with capsid binder compound 17 | | 分子名称: | 4-[[4-[1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]sulfonylamino]benzoic acid, MYRISTIC ACID, capsid protein VP1, ... | | 著者 | Domanska, A, Flatt, J.W, Butcher, S.J. | | 登録日 | 2020-06-11 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Identification of a conserved virion-stabilizing network inside the interprotomer pocket of enteroviruses.
Commun Biol, 4, 2021
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8S7J
 | | Coxsackievirus A9 bound with compound 20 (CL300) | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Plavec, Z, Butcher, S.J, Mitchell, C, Buckner, C. | | 登録日 | 2024-03-01 | | 公開日 | 2024-10-02 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | | 主引用文献 | SAR Analysis of Novel Coxsackie virus A9 Capsid Binders.
J.Med.Chem., 67, 2024
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5APM
 | | Multiple capsid-stabilizing protein-RNA and protein-protein interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis | | 分子名称: | VP0, VP1, VP3 | | 著者 | Shakeel, S, Westerhuis, B.M, Domanska, A, Koning, R.I, Matadeen, R, Koster, A.J, Bakker, A.Q, Beaumont, T, Wolthers, K.C, Butcher, S.J. | | 登録日 | 2015-09-17 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Multiple Capsid-Stabilizing Interactions Revealed in a High-Resolution Structure of an Emerging Picornavirus Causing Neonatal Sepsis
Nat.Commun., 7, 2016
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5MJV
 | | Rebuild and re-refined model for Human Parechovirus 1 | | 分子名称: | CAPSID SUBUNIT VP0, CAPSID SUBUNIT VP1, CAPSID SUBUNIT VP3, ... | | 著者 | Shakeel, S, Dykeman, E.C, White, S.J, Ora, A, Cockburn, J.J.B, Butcher, S.J, Stockley, P.G, Twarock, R. | | 登録日 | 2016-12-01 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Genomic RNA folding mediates assembly of human parechovirus.
Nat Commun, 8, 2017
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6O06
 | | Extracellular factors prime enterovirus particles for uncoating | | 分子名称: | VP1, VP2, VP3 | | 著者 | Domanska, A, Ruokolainen, V, Pelliccia, M, Laajala, M, Butcher, S.J, Marjomaki, V.S. | | 登録日 | 2019-02-15 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Extracellular Albumin and Endosomal Ions Prime Enterovirus Particles for Uncoating That Can Be Prevented by Fatty Acid Saturation.
J.Virol., 93, 2019
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3J2J
 | | Empty coxsackievirus A9 capsid | | 分子名称: | Protein VP1, Protein VP2, Protein VP3 | | 著者 | Shakeel, S, Seitsonen, J.J.T, Kajander, T, Laurinmaki, P, Hyypia, T, Susi, P, Butcher, S.J. | | 登録日 | 2012-10-04 | | 公開日 | 2013-07-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (9.54 Å) | | 主引用文献 | Structural and functional analysis of coxsackievirus A9 integrin {alpha}v{beta}6 binding and uncoating.
J.Virol., 87, 2013
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5E4V
 | | Crystal structure of measles N0-P complex | | 分子名称: | Nucleoprotein,Phosphoprotein | | 著者 | Guryanov, S.G, Liljeroos, L, Kasaragod, P, Kajander, T, Butcher, S.J. | | 登録日 | 2015-10-07 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Crystal Structure of the Measles Virus Nucleoprotein Core in Complex with an N-Terminal Region of Phosphoprotein.
J.Virol., 90, 2015
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4BIP
 | | Homology model of coxsackievirus A7 (CAV7) full capsid proteins. | | 分子名称: | VP1, VP2, VP3 | | 著者 | Seitsonen, J.J.T, Shakeel, S, Susi, P, Pandurangan, A.P, Sinkovits, R.S, Hyvonen, H, Laurinmaki, P, Yla-Pelto, J, Topf, M, Hyypia, T, Butcher, S.J. | | 登録日 | 2013-04-12 | | 公開日 | 2013-10-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (8.23 Å) | | 主引用文献 | Combined Approaches to Flexible Fitting and Assessment in Virus Capsids Undergoing Conformational Change.
J.Struct.Biol., 185, 2014
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4BIQ
 | | Homology model of coxsackievirus A7 (CAV7) empty capsid proteins. | | 分子名称: | VP1, VP2, VP3 | | 著者 | Seitsonen, J.J.T, Shakeel, S, Susi, P, Pandurangan, A.P, Sinkovits, R.S, Hyvonen, H, Laurinmaki, P, Yla-Pelto, J, Topf, M, Hyypia, T, Butcher, S.J. | | 登録日 | 2013-04-12 | | 公開日 | 2013-10-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (6.09 Å) | | 主引用文献 | Combined Approaches to Flexible Fitting and Assessment in Virus Capsids Undergoing Conformational Change.
J.Struct.Biol., 185, 2014
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4UDF
 | | STRUCTURAL BASIS OF HUMAN PARECHOVIRUS NEUTRALIZATION BY HUMAN MONOCLONAL ANTIBODIES | | 分子名称: | HUMAN MONOCLONAL ANTIBODY, Protein VP0, Protein VP3 | | 著者 | Shakeel, S, Westerhuis, B.M, Ora, A, Koen, G, Bakker, A.Q, Claassen, Y, Beaumont, T, Wolthers, K.C, Butcher, S.J. | | 登録日 | 2014-12-10 | | 公開日 | 2015-07-22 | | 最終更新日 | 2018-10-03 | | 実験手法 | ELECTRON MICROSCOPY (20 Å) | | 主引用文献 | Structural Basis of Human Parechovirus Neutralization by Human Monoclonal Antibodies.
J. Virol., 89, 2015
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5MM2
 | | nora virus structure | | 分子名称: | Capsid protein VP4A, capsid protein VP4B, capsid protein VP4C | | 著者 | Laurinmaki, P, Shakeel, S, Ekstrom, J.-O, Butcher, S.J. | | 登録日 | 2016-12-08 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structure of Nora virus at 2.7 angstrom resolution and implications for receptor binding, capsid stability and taxonomy.
Sci Rep, 10, 2020
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6GV4
 | | High-resolution Cryo-EM of Fab-labeled human parechovirus 3 | | 分子名称: | AT12-015 antibody variable heavy, AT12-015 antibody variable light, RNA (5'-R(*UP*GP*GP*UP*AP*UP*UP*U)-3'), ... | | 著者 | Domanska, A, Flatt, J.W, Jukonen, J.J.J, Geraets, J.A, Butcher, S.J. | | 登録日 | 2018-06-20 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | A 2.8-Angstrom-Resolution Cryo-Electron Microscopy Structure of Human Parechovirus 3 in Complex with Fab from a Neutralizing Antibody.
J.Virol., 93, 2019
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6GZV
 | | Identification of a druggable VP1-VP3 interprotomer pocket in the capsid of enteroviruses | | 分子名称: | 4-[[4-[1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]sulfonylamino]benzoic acid, Capsid protein VP1, Capsid protein VP2, ... | | 著者 | Geraets, J.A, Flatt, J.W, Domanska, A, Butcher, S.J. | | 登録日 | 2018-07-05 | | 公開日 | 2019-06-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses.
Plos Biol., 17, 2019
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9FJD
 | | Expanded CVB1-VLP (Tween80) | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | | 著者 | Plavec, Z, Butcher, S.J. | | 登録日 | 2024-05-31 | | 公開日 | 2024-07-31 | | 実験手法 | ELECTRON MICROSCOPY (2.15 Å) | | 主引用文献 | Comparison of structure and immunogenicity of CVB1-VLP and inactivated CVB1 vaccine candidates.
Res Sq, 2024
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