8S7J

Coxsackievirus A9 bound with compound 20 (CL300)

This is a non-PDB format compatible entry.

Summary for 8S7J

• Entry DOI: 10.2210/pdb8s7j/pdb
• EMDB information: 19774
• Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... (6 entities in total)
• Functional Keywords: antiviral, capsid stabilizer, hydrophobic pocket, cryoem, virus
• Biological source: Human coxsackievirus A9 (strain Griggs); More
• Total number of polymer chains: 4
• Total formula weight: 96995.47

Authors

Plavec, Z.,Butcher, S.J.,Mitchell, C.,Buckner, C. (deposition date: 2024-03-01, release date: 2024-10-02)

• Primary citation: Tammaro, C.,Plavec, Z.,Myllymaki, L.,Mitchell, C.,Consalvi, S.,Biava, M.,Ciogli, A.,Domanska, A.,Leppilampi, V.,Buckner, C.,Manetto, S.,Scio, P.,Coluccia, A.,Laajala, M.,Dondio, G.M.,Bigogno, C.,Marjomaki, V.,Butcher, S.J.,Poce, G.; SAR Analysis of Novel Coxsackie virus A9 Capsid Binders.; J.Med.Chem., 2024; PubMed: 39292620; DOI: 10.1021/acs.jmedchem.4c00701

Experimental method

ELECTRON MICROSCOPY (2.26 Å)