5NW5
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![BU of 5nw5 by Molmil](/molmil-images/mine/5nw5) | Crystal structure of the Rif1 N-terminal domain (RIF1-NTD) from Saccharomyces cerevisiae in complex with DNA | Descriptor: | DNA (30-MER), DNA (60-MER), Telomere length regulator protein RIF1 | Authors: | Bunker, R.D, Reinert, J.K, Shi, T, Thoma, N.H. | Deposit date: | 2017-05-05 | Release date: | 2017-06-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (6.502 Å) | Cite: | Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends. Nat. Struct. Mol. Biol., 24, 2017
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2FE1
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![BU of 2fe1 by Molmil](/molmil-images/mine/2fe1) | Crystal Structure of PAE0151 from Pyrobaculum aerophilum | Descriptor: | CALCIUM ION, CHLORIDE ION, MANGANESE (II) ION, ... | Authors: | Bunker, R.D, Baker, E.N, Arcus, V.L. | Deposit date: | 2005-12-15 | Release date: | 2005-12-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of PAE0151 from Pyrobaculum aerophilum, a PIN-domain (VapC) protein from a toxin-antitoxin operon. Proteins, 72, 2008
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5NVR
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![BU of 5nvr by Molmil](/molmil-images/mine/5nvr) | |
5G3X
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![BU of 5g3x by Molmil](/molmil-images/mine/5g3x) | Structure of recombinant granulovirus polyhedrin | Descriptor: | GRANULOVIRUS POLYHEDRIN | Authors: | Bunker, R.D, Chiu, E, Metcalf, P. | Deposit date: | 2016-05-02 | Release date: | 2017-02-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Atomic structure of granulin determined from native nanocrystalline granulovirus using an X-ray free-electron laser. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6YNG
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6TD3
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![BU of 6td3 by Molmil](/molmil-images/mine/6td3) | Structure of DDB1 bound to CR8-engaged CDK12-cyclinK | Descriptor: | (2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol, Cyclin-K, Cyclin-dependent kinase 12, ... | Authors: | Bunker, R.D, Petzold, G, Kozicka, Z, Thoma, N.H. | Deposit date: | 2019-11-07 | Release date: | 2020-06-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.46 Å) | Cite: | The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K. Nature, 585, 2020
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6GVW
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![BU of 6gvw by Molmil](/molmil-images/mine/6gvw) | Crystal structure of the BRCA1-A complex | Descriptor: | BRCA1-A complex subunit Abraxas 1, BRCA1-A complex subunit RAP80, BRISC and BRCA1-A complex member 1, ... | Authors: | Bunker, R.D, Rabl, J, Thoma, N.H. | Deposit date: | 2018-06-21 | Release date: | 2019-07-10 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (3.75 Å) | Cite: | Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation. Mol.Cell, 75, 2019
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6H0G
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![BU of 6h0g by Molmil](/molmil-images/mine/6h0g) | Structure of the DDB1-CRBN-pomalidomide complex bound to ZNF692(ZF4) | Descriptor: | DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1,DDB1 (DNA damage binding protein 1),DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1, Protein cereblon, S-Pomalidomide, ... | Authors: | Bunker, R.D, Petzold, G, Thoma, N.H. | Deposit date: | 2018-07-09 | Release date: | 2018-11-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (4.25 Å) | Cite: | Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN. Science, 362, 2018
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6H3C
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![BU of 6h3c by Molmil](/molmil-images/mine/6h3c) | Cryo-EM structure of the BRISC complex bound to SHMT2 | Descriptor: | BRISC and BRCA1-A complex member 1, BRISC and BRCA1-A complex member 2, BRISC complex subunit Abraxas 2, ... | Authors: | Bunker, R.D, Rabl, J, Thoma, N.H. | Deposit date: | 2018-07-18 | Release date: | 2019-07-10 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation. Mol.Cell, 75, 2019
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4D18
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![BU of 4d18 by Molmil](/molmil-images/mine/4d18) | Crystal structure of the COP9 signalosome | Descriptor: | COP9 SIGNALOSOME COMPLEX SUBUNIT 1, COP9 SIGNALOSOME COMPLEX SUBUNIT 2, COP9 SIGNALOSOME COMPLEX SUBUNIT 3, ... | Authors: | Bunker, R.D, Lingaraju, G.M, Thoma, N.H. | Deposit date: | 2014-05-01 | Release date: | 2014-07-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (4.08 Å) | Cite: | Crystal Structure of the Human Cop9 Signalosome Nature, 512, 2014
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4D0P
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![BU of 4d0p by Molmil](/molmil-images/mine/4d0p) | Crystal structure of human CSN4 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, COP9 SIGNALOSOME COMPLEX SUBUNIT 4, ... | Authors: | Bunker, R.D, Lingaraju, G.M, Thoma, N.H. | Deposit date: | 2014-04-29 | Release date: | 2014-07-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of the Cop9 Signalosome Nature, 512, 2014
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4D10
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![BU of 4d10 by Molmil](/molmil-images/mine/4d10) | Crystal structure of the COP9 signalosome | Descriptor: | COP9 SIGNALOSOME COMPLEX SUBUNIT 1, COP9 SIGNALOSOME COMPLEX SUBUNIT 2, COP9 SIGNALOSOME COMPLEX SUBUNIT 3, ... | Authors: | Bunker, R.D, Lingaraju, G.M, Thoma, N.H. | Deposit date: | 2014-04-30 | Release date: | 2014-07-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Crystal Structure of the Human Cop9 Signalosome Nature, 512, 2014
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4WSN
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![BU of 4wsn by Molmil](/molmil-images/mine/4wsn) | Crystal structure of the COP9 signalosome, a P1 crystal form | Descriptor: | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... | Authors: | Bunker, R.D, Lingaraju, G.M, Thoma, N.H. | Deposit date: | 2014-10-28 | Release date: | 2015-12-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (5.5 Å) | Cite: | Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome. Nature, 531, 2016
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4WSP
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![BU of 4wsp by Molmil](/molmil-images/mine/4wsp) | Racemic crystal structure of Rv1738 from Mycobacterium tuberculosis (Form-I) | Descriptor: | CHLORIDE ION, protein DL-Rv1738 | Authors: | Bunker, R.D, Mandal, K, Kent, S.B.H, Baker, E.N. | Deposit date: | 2014-10-28 | Release date: | 2015-03-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography. Proc.Natl.Acad.Sci.USA, 112, 2015
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4WPY
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![BU of 4wpy by Molmil](/molmil-images/mine/4wpy) | Racemic crystal structure of Rv1738 from Mycobacterium tuberculosis (Form-II) | Descriptor: | GLYCEROL, protein DL-Rv1738, trifluoroacetic acid | Authors: | Bunker, R.D, Mandal, K, Kent, S.B.H, Baker, E.N. | Deposit date: | 2014-10-21 | Release date: | 2015-03-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography. Proc.Natl.Acad.Sci.USA, 112, 2015
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4BC4
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![BU of 4bc4 by Molmil](/molmil-images/mine/4bc4) | Crystal structure of human D-xylulokinase in complex with D-xylulose | Descriptor: | 1,2-ETHANEDIOL, D-XYLULOSE, XYLULOSE KINASE | Authors: | Bunker, R.D, Loomes, K.M, Baker, E.N. | Deposit date: | 2012-10-01 | Release date: | 2012-11-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism J.Biol.Chem., 288, 2013
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4BC5
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![BU of 4bc5 by Molmil](/molmil-images/mine/4bc5) | Crystal structure of human D-xylulokinase in complex with inhibitor 5- deoxy-5-fluoro-D-xylulose | Descriptor: | 1,2-ETHANEDIOL, 5-deoxy-5-fluoro-D-xylulose, XYLULOSE KINASE | Authors: | Bunker, R.D, Loomes, K.M, Baker, E.N. | Deposit date: | 2012-10-01 | Release date: | 2012-11-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism J.Biol.Chem., 288, 2013
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4BC2
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![BU of 4bc2 by Molmil](/molmil-images/mine/4bc2) | Crystal structure of human D-xylulokinase in complex with D-xylulose and adenosine diphosphate | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, D-XYLULOSE, ... | Authors: | Bunker, R.D, Loomes, K.M, Baker, E.N. | Deposit date: | 2012-10-01 | Release date: | 2012-11-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism J.Biol.Chem., 288, 2013
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4BC3
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![BU of 4bc3 by Molmil](/molmil-images/mine/4bc3) | Crystal structure of human D-xylulokinase | Descriptor: | 1,2-ETHANEDIOL, XYLULOSE KINASE | Authors: | Bunker, R.D, Loomes, K.M, Baker, E.N. | Deposit date: | 2012-10-01 | Release date: | 2012-11-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism J.Biol.Chem., 288, 2013
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4BJS
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![BU of 4bjs by Molmil](/molmil-images/mine/4bjs) | Crystal structure of the Rif1 C-terminal domain (Rif1-CTD) from Saccharomyces cerevisiae | Descriptor: | TELOMERE LENGTH REGULATOR PROTEIN RIF1 | Authors: | Bunker, R.D, Shi, T, Gut, H, Scrima, A, Thoma, N.H. | Deposit date: | 2013-04-19 | Release date: | 2013-06-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions Cell(Cambridge,Mass.), 153, 2013
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3KLQ
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![BU of 3klq by Molmil](/molmil-images/mine/3klq) | Crystal Structure of the Minor Pilin FctB from Streptococcus pyogenes 90/306S | Descriptor: | GLYCEROL, Putative pilus anchoring protein | Authors: | Linke, C, Young, P.G, Bunker, R.D, Caradoc-Davies, T.T, Baker, E.N. | Deposit date: | 2009-11-08 | Release date: | 2010-04-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the minor pilin FctB reveals determinants of Group A streptococcal pilus anchoring J.Biol.Chem., 285, 2010
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2YB8
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![BU of 2yb8 by Molmil](/molmil-images/mine/2yb8) | Crystal structure of Nurf55 in complex with Su(z)12 | Descriptor: | POLYCOMB PROTEIN SU(Z)12, PROBABLE HISTONE-BINDING PROTEIN CAF1, SULFATE ION | Authors: | Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H. | Deposit date: | 2011-03-02 | Release date: | 2011-05-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks. Mol.Cell, 42, 2011
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2YBA
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![BU of 2yba by Molmil](/molmil-images/mine/2yba) | Crystal structure of Nurf55 in complex with histone H3 | Descriptor: | HISTONE H3, PROBABLE HISTONE-BINDING PROTEIN CAF1 | Authors: | Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H. | Deposit date: | 2011-03-02 | Release date: | 2011-05-11 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks Mol.Cell, 42, 2011
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6R8Z
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![BU of 6r8z by Molmil](/molmil-images/mine/6r8z) | Cryo-EM structure of NCP_THF2(-1)-UV-DDB | Descriptor: | DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | Authors: | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | Deposit date: | 2019-04-02 | Release date: | 2019-06-12 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
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6R94
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![BU of 6r94 by Molmil](/molmil-images/mine/6r94) | Cryo-EM structure of NCP_THF2(-3) | Descriptor: | Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ... | Authors: | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | Deposit date: | 2019-04-02 | Release date: | 2019-06-12 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
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