8OLA
 
 | | Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor VK4 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{R},8~{R},9~{S},10~{S},13~{S},14~{S},17~{S})-17-ethanoyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-30 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl
To Be Published
|
|
8OKJ
 | | Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor AKI_12 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{S},8~{R},9~{S},10~{S},13~{S},14~{S},17~{S})-17-ethanoyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-28 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl
To Be Published
|
|
8OKP
 | | Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor AKI_33 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{R},8~{R},9~{S},10~{S},13~{S},14~{S},15~{R})-10,13,15-trimethyl-17-oxidanylidene-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-28 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl
To Be Published
|
|
8OKT
 | | Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor VK42 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(8~{R},9~{S},13~{S},14~{S})-13-methyl-17-oxidanylidene-7,8,9,11,12,14,15,16-octahydro-6~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-29 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl
To Be Published
|
|
8OMN
 | | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl VK4 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{R},8~{R},9~{S},10~{S},13~{S},14~{S},17~{S})-17-ethanoyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-31 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl
To Be Published
|
|
8OKE
 | | Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor AKI_1 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{S},8~{R},9~{S},10~{R},13~{S},14~{S})-10,13-dimethyl-17-oxidanylidene-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-28 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl
To Be Published
|
|
8OLK
 | |
8OLF
 | | Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor BS1982 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(8~{S},9~{S},13~{S},14~{S})-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-30 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl
To Be Published
|
|
8OKQ
 | | Carbonic Anhydrase 2 in Complex with Steriod_Sulphamoyl AKI_2 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{S},8~{R},9~{S},10~{R},13~{S},14~{S})-10,13-dimethyl-17-oxidanylidene-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-29 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Carbonic Anhydrase in Complex with Steriod_Sulphamoyl
To Be Published
|
|
8OLM
 | | Carbonic Anhydrase 2 in Complex with Steriod_Sulphamoyl AKI1 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{S},5~{S},8~{S},13~{R},14~{R})-5,14-dimethyl-16-oxidanylidene-1,2,3,4,6,7,8,11,12,13,15,17-dodecahydrocyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-30 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Carbonic Anhydrase in Complex with Steriod_Sulphamoyl
To Be Published
|
|
8OMP
 | | Carbonic Anhydrase 2 in Complex with Steriod_Sulphamoyl AKI33 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{R},8~{R},9~{S},10~{S},13~{S},14~{S},15~{R})-10,13,15-trimethyl-17-oxidanylidene-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-31 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Carbonic Anhydrase in Complex with Steriod_Sulphamoyl
To Be Published
|
|
8OKO
 | | Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor AKI_2 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{S},8~{S},9~{S},10~{R},13~{S},14~{S})-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-28 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl
To Be Published
|
|
8OLI
 | | Carbonic Anhydrase 2 in Complex with Steriod_Sulphamoyl AKI_12 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{S},8~{R},9~{S},10~{S},13~{S},14~{S},17~{S})-17-ethanoyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-30 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Carbonic Anhydrase in Complex with Steriod_Sulphamoyl
To Be Published
|
|
8OMB
 | | Carbonic Anhydrase 2 in Complex with Steriod_Sulphamoyl VK42 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(8~{R},9~{S},13~{S},14~{S})-13-methyl-17-oxidanylidene-7,8,9,11,12,14,15,16-octahydro-6~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-31 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Carbonic Anhydrase in Complex with Steriod_Sulphamoyl
To Be Published
|
|
8OMH
 | | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl (BS1982) | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(8~{S},9~{S},13~{S},14~{S})-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-31 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl
To Be Published
|
|
8OKG
 | | Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor AKI_13 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{S},8~{S},9~{S},10~{R},13~{S},14~{S},17~{S})-17-methanoyl-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-28 | | 公開日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl
To Be Published
|
|
2R96
 | | Crystal structure of E. coli WrbA in complex with FMN | | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, Flavoprotein WrbA | | 著者 | Kuta Smatanova, I, Wolfova, J, Brynda, J, Mesters, J.R, Grandori, R, Carey, J. | | 登録日 | 2007-09-12 | | 公開日 | 2008-09-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural organization of WrbA in apo- and holoprotein crystals.
Biochim.Biophys.Acta, 1794, 2009
|
|
2G98
 | | human gamma-D-crystallin | | 分子名称: | Gamma crystallin D | | 著者 | Kmoch, S, Brynda, J, Awsav, B, Bezouska, K, Novak, P, Rezacova, P. | | 登録日 | 2006-03-06 | | 公開日 | 2006-05-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Link between a novel human gamma-D-crystallin allele and a unique cataract phenotype explained by protein crystallography.
Hum.Mol.Genet., 12, 2000
|
|
3L0R
 | | Crystal Structure of Salivary Cystatin from the Soft Tick Ornithodoros moubata | | 分子名称: | CHLORIDE ION, Cystatin-2, GLYCEROL | | 著者 | Rezacova, P, Brynda, J, Andersen, J.F, Salat, J, Kovarova, Z, Mares, M. | | 登録日 | 2009-12-10 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata
Biochem.J., 429, 2010
|
|
1N4X
 | | Structure of scFv 1696 at acidic pH | | 分子名称: | CHLORIDE ION, immunoglobulin heavy chain variable region, immunoglobulin kappa chain variable region | | 著者 | Lescar, J, Brynda, J, Fabry, M, Horejsi, M, Rezacova, P, Sedlacek, J, Bentley, G.A. | | 登録日 | 2002-11-02 | | 公開日 | 2003-06-10 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of a single-chain Fv fragment of an antibody that inhibits the HIV-1 and HIV-2 proteases.
Acta Crystallogr.,Sect.D, 59, 2003
|
|
6R5H
 | | Major aspartyl peptidase 1 from C. neoformans | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ... | | 著者 | Krystufek, R, Sacha, P, Brynda, J, Konvalinka, J. | | 登録日 | 2019-03-25 | | 公開日 | 2021-04-07 | | 最終更新日 | 2021-06-09 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
J.Med.Chem., 64, 2021
|
|
6R6A
 | | Major aspartyl peptidase 1 from C. neoformans | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Endopeptidase, ... | | 著者 | Krystufek, R, Sacha, P, Brynda, J, Konvalinka, J. | | 登録日 | 2019-03-26 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
J.Med.Chem., 64, 2021
|
|
3TNE
 | | The crystal structure of protease Sapp1p from Candida parapsilosis in complex with the HIV protease inhibitor ritonavir | | 分子名称: | RITONAVIR, Secreted aspartic protease | | 著者 | Dostal, J, Brynda, J, Hruskova-Heidingsfeldova, O, Pachl, P, Pichova, I, Rezacova, P. | | 登録日 | 2011-09-01 | | 公開日 | 2012-03-07 | | 最終更新日 | 2012-12-12 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The crystal structure of protease Sapp1p from Candida parapsilosis in complex with the HIV protease inhibitor ritonavir.
J Enzyme Inhib Med Chem, 27, 2012
|
|
3U7S
 | | HIV PR drug resistant patient's variant in complex with darunavir | | 分子名称: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, BETA-MERCAPTOETHANOL, Pol polyprotein | | 著者 | Saskova, K.G, Rezacova, P, Konvalinka, J, Brynda, J, Kozisek, M. | | 登録日 | 2011-10-14 | | 公開日 | 2012-01-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Molecular characterization of clinical isolates of human immunodeficiency virus resistant to the protease inhibitor darunavir.
J.Virol., 83, 2009
|
|
6R61
 | | Major aspartyl peptidase 1 from C. neoformans in complex with Inhibitor LP258 | | 分子名称: | (3~{S},7~{S},8~{S})-7-oxidanyl-8-(phenylmethyl)-3-(pyridin-2-ylmethyl)-1,4,9-triazacyclotricosane-2,5,10-trione, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Krystufek, R, Sacha, P, Brynda, J, Konvalinka, J. | | 登録日 | 2019-03-26 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Major aspartyl peptidase 1 from C. neoformans in complex with Inhibitor LP258
To Be Published
|
|
