Summary for 3U7S
| Entry DOI | 10.2210/pdb3u7s/pdb |
| Related | 1GGU |
| Descriptor | Pol polyprotein, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, BETA-MERCAPTOETHANOL, ... (4 entities in total) |
| Functional Keywords | darunvir, resistance, mutation score, hiv protease, tmc-114, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Human immunodeficiency virus 1 (HIV-1) |
| Total number of polymer chains | 2 |
| Total formula weight | 22930.96 |
| Authors | Saskova, K.G.,Rezacova, P.,Konvalinka, J.,Brynda, J.,Kozisek, M. (deposition date: 2011-10-14, release date: 2012-01-18, Last modification date: 2024-02-28) |
| Primary citation | Saskova, K.G.,Kozisek, M.,Rezacova, P.,Brynda, J.,Yashina, T.,Kagan, R.M.,Konvalinka, J. Molecular characterization of clinical isolates of human immunodeficiency virus resistant to the protease inhibitor darunavir. J.Virol., 83:8810-8818, 2009 Cited by PubMed: 19535439DOI: 10.1128/JVI.00451-09 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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