Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Pol polyprotein | polymer | 99 | 10839.7 | 2 | UniProt (Q993Q5) Pfam (PF00077) UniProt (by SIFTS) (P03367) | Human immunodeficiency virus 1 (HIV-1) | HIV protease |
| 2 | C, D (A) | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE | non-polymer | 547.7 | 2 | Chemie (017) | |||
| 3 | E, F (A, B) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 173 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: Q993Q5)
| PDB | External Database | Details |
|---|---|---|
| Leu 10 | Ile 18 | engineered mutation |
| Val 12 | Thr 20 | engineered mutation |
| Ile 32 | Val 40 | engineered mutation |
| Phe 33 | Leu 41 | engineered mutation |
| Thr 43 | Lys 51 | engineered mutation |
| Leu 54 | Val 62 | engineered mutation |
| Asn 55 | Lys 63 | engineered mutation |
| Val 72 | Ile 80 | engineered mutation |
| Ile 77 | Val 85 | engineered mutation |
| Leu 82 | Val 90 | engineered mutation |
| Val 89 | Leu 97 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21679.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1251.6 | |
| All* | Total formula weight | 22931.0 |
