Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 1240 results

2WM8
DownloadVisualize
BU of 2wm8 by Molmil
Crystal structure of human magnesium-dependent phosphatase 1 of the haloacid dehalogenase superfamily (MGC5987)
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM-DEPENDENT PHOSPHATASE 1
Authors:Yue, W.W, Shafqat, N, Pike, A.C.W, Chaikuad, A, Bray, J.E, Pilka, E.W, Burgess-Brown, N, Hapka, E, Filippakopoulos, P, von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U.
Deposit date:2009-06-30
Release date:2009-07-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure of Human Magnesium-Dependent Phosphatase 1 of the Haloacid Dehalogenase Superfamily (Mgc5987)
To be Published
5NKS
DownloadVisualize
BU of 5nks by Molmil
Human Dihydropyrimidinase-related Protein 4 (DPYSL4, CRMP3, ULIP-4)
Descriptor: Dihydropyrimidinase-related protein 4
Authors:Mathea, S, Elkins, J.M, Strain-Damerell, C, Salah, E, Borkowska, O, Chalk, R, Burgess-Brown, N, Pinkas, D.M, von Delft, F, Krojer, T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S.
Deposit date:2017-03-31
Release date:2017-11-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Human Dihydropyrimidinase-related Protein 4 (DPYSL4, CRMP3, ULIP-4)
To Be Published
2WO6
DownloadVisualize
BU of 2wo6 by Molmil
Human Dual-Specificity Tyrosine-Phosphorylation-Regulated Kinase 1A in complex with a consensus substrate peptide
Descriptor: ARTIFICIAL CONSENSUS SEQUENCE, CHLORIDE ION, DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION- REGULATED KINASE 1A, ...
Authors:Roos, A.K, Soundararajan, M, Elkins, J.M, Fedorov, O, Eswaran, J, Phillips, C, Pike, A.C.W, Ugochukwu, E, Muniz, J.R.C, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Wikstrom, M, Edwards, A, Bountra, C, Knapp, S.
Deposit date:2009-07-22
Release date:2009-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of Down Syndrome Kinases, Dyrks, Reveal Mechanisms of Kinase Activation and Substrate Recognition.
Structure, 21, 2013
2VZ6
DownloadVisualize
BU of 2vz6 by Molmil
Structure of human calcium calmodulin dependent protein kinase type II alpha (CAMK2A) in complex with Indirubin E804
Descriptor: (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}, CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE TYPE II ALPHA CHAIN, S-1,2-PROPANEDIOL
Authors:Pike, A.C.W, Rellos, P, King, O, Salah, E, Parizotto, E, Fedorov, O, Shrestha, L, Burgess-Brown, N, Roos, A, Murray, J.W, von Delft, F, Edwards, A, Arrowsmith, C.H, Wikstroem, M, Bountra, C, Knapp, S.
Deposit date:2008-07-30
Release date:2008-08-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Camkiidelta/Calmodulin Complex Reveals the Molecular Mechanism of Camkii Kinase Activation.
Plos Biol., 8, 2010
2V7O
DownloadVisualize
BU of 2v7o by Molmil
Crystal structure of human calcium-calmodulin-dependent protein kinase II gamma
Descriptor: 1,2-ETHANEDIOL, BISINDOLYLMALEIMIDE IX, CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II GAMMA CHAIN
Authors:Pike, A.C.W, Rellos, P, Fedorov, O, Burgess-Brown, N, Shrestha, L, Ugochukwu, E, Pilka, E.S, von Delft, F, Edwards, A, Weigelt, J, Arrowsmith, C.H, Sundstrom, M, Knapp, S.
Deposit date:2007-07-31
Release date:2007-09-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of the Camkiidelta/Calmodulin Complex Reveals the Molecular Mechanism of Camkii Kinase Activation.
Plos Biol., 8, 2010
2UZC
DownloadVisualize
BU of 2uzc by Molmil
Structure of human PDLIM5 in complex with the C-terminal peptide of human alpha-actinin-1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, PDZ AND LIM DOMAIN 5
Authors:Bunkoczi, G, Elkins, J, Salah, E, Burgess-Brown, N, Papagrigoriou, E, Pike, A.C.W, Turnbull, A, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Weigelt, J, Doyle, D.
Deposit date:2007-04-27
Release date:2007-05-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms.
Protein Sci., 19, 2010
2V1W
DownloadVisualize
BU of 2v1w by Molmil
Crystal structure of human LIM protein RIL (PDLIM4) PDZ domain bound to the C-terminal peptide of human alpha-actinin-1
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, PDZ AND LIM DOMAIN PROTEIN 4, ...
Authors:Soundararajan, M, Shrestha, L, Pike, A.C.W, Salah, E, Burgess-Brown, N, Elkins, J, Umeano, C, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Doyle, D.
Deposit date:2007-05-30
Release date:2007-06-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Unusual Binding Interactions in Pdz Domain Crystal Structures Help Explain Binding Mechanisms.
Protein Sci., 19, 2010
2VUW
DownloadVisualize
BU of 2vuw by Molmil
Structure of human haspin kinase domain
Descriptor: (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, DIMETHYL SULFOXIDE, ...
Authors:Eswaran, J, Murray, J.W, Filippakopoulos, P, Soundararajan, M, Pike, A.C.W, von Delft, F, Picaud, S, Keates, T, King, O, Wickstroem, M, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Fedorov, O, Burgess-Brown, N, Bray, J, Knapp, S.
Deposit date:2008-05-30
Release date:2008-09-16
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and Functional Characterization of the Atypical Human Kinase Haspin.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WA0
DownloadVisualize
BU of 2wa0 by Molmil
Crystal structure of the human MAGEA4
Descriptor: MELANOMA-ASSOCIATED ANTIGEN 4
Authors:Roos, A.K, Cooper, C.D.O, Ugochukwu, E, W Yue, W, Berridge, G, Elkins, J.M, Pike, A.C.W, Bray, J, Filippakopoulos, P, Muniz, J, Chaikuad, A, Burgess-Brown, N, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, von Delft, F, Gileadi, O, Oppermann, U.
Deposit date:2009-01-31
Release date:2009-03-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.
Plos One, 11, 2016
2W2C
DownloadVisualize
BU of 2w2c by Molmil
STRUCTURE OF THE TETRADECAMERIC OLIGOMERISATION DOMAIN OF CALCIUM- CALMODULIN DEPENDENT PROTEIN KINASE II DELTA
Descriptor: ACETATE ION, CADMIUM ION, CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II DELTA CHAIN
Authors:Pike, A.C.W, Rellos, P, Sethi, R, Salah, E, Burgess-Brown, N, Shrestha, L, Roos, A, Murray, J.W, von Delft, F, Edwards, A, Arrowsmith, C.H, Weigelt, J, Bountra, C, Knapp, S.
Deposit date:2008-10-28
Release date:2008-12-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the Camkiidelta/Calmodulin Complex Reveals the Molecular Mechanism of Camkii Kinase Activation.
Plos Biol., 8, 2010
2WWW
DownloadVisualize
BU of 2www by Molmil
Crystal Structure of Methylmalonic Acidemia Type A Protein
Descriptor: GUANOSINE-5'-DIPHOSPHATE, METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL, ...
Authors:Muniz, J.R.C, Gileadi, C, Froese, D.S, Yue, W.W, Pike, A.C.W, von Delft, F, Kochan, G, Sethi, R, Chaikuad, A, Pilka, E, Picaud, S, Phillips, C, Guo, K, Krysztofinska, E, Bray, J, Burgess-Brown, N, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Gravel, R.A, Kavanagh, K.L, Oppermann, U.
Deposit date:2009-10-30
Release date:2009-11-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structures of the Human Gtpase Mmaa and Vitamin B12-Dependent Methylmalonyl-Coa Mutase and Insight Into Their Complex Formation.
J.Biol.Chem., 285, 2010
5RAZ
DownloadVisualize
BU of 5raz by Molmil
PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM010013a
Descriptor: CHLORIDE ION, Lysine-specific demethylase 3B, MANGANESE (II) ION, ...
Authors:Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U.
Deposit date:2020-03-16
Release date:2020-04-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library
To Be Published
5R5H
DownloadVisualize
BU of 5r5h by Molmil
PanDDA analysis group deposition -- Crystal Structure of human NUDT22 in complex with N13706a
Descriptor: 3-chloro-N-(1-hydroxy-2-methylpropan-2-yl)benzamide, DIMETHYL SULFOXIDE, Uridine diphosphate glucose pyrophosphatase NUDT22
Authors:Diaz-Saez, L, Talon, R, Krojer, T, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Huber, K.V.M.
Deposit date:2020-02-28
Release date:2020-07-01
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:PanDDA analysis group deposition
To Be Published
5RB7
DownloadVisualize
BU of 5rb7 by Molmil
PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001648a
Descriptor: (1R,3S)-N-[(2H-1,3-benzodioxol-5-yl)methyl]-3-methylcyclopentan-1-amine, CHLORIDE ION, Lysine-specific demethylase 3B, ...
Authors:Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U.
Deposit date:2020-03-16
Release date:2020-04-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library
To Be Published
4QC1
DownloadVisualize
BU of 4qc1 by Molmil
Crystal structure of human BAZ2B bromodomain in complex with an acetylated histone 3 peptide (H3K14ac)
Descriptor: Bromodomain adjacent to zinc finger domain protein 2B, SULFATE ION, ZINC ION, ...
Authors:Tallant, C, Jose, B, Picaud, S, Chaikuad, A, Filippakopoulos, P, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2014-05-09
Release date:2014-05-21
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC.
Structure, 23, 2015
4QC3
DownloadVisualize
BU of 4qc3 by Molmil
Crystal structure of human BAZ2B bromodomain in complex with a diacetylated histone 4 peptide (H4K8acK12ac)
Descriptor: 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B, diacetylated histone 4 peptide (H4K8acK12ac)
Authors:Tallant, C, Jose, B, Picaud, S, Chaikuad, A, Filippakopoulos, P, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2014-05-09
Release date:2014-05-21
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC.
Structure, 23, 2015
5S81
DownloadVisualize
BU of 5s81 by Molmil
XChem group deposition -- Crystal Structure of human ACVR1 in complex with FM010947a
Descriptor: 1,2-ETHANEDIOL, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, Activin receptor type-1, ...
Authors:Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N.
Deposit date:2020-12-11
Release date:2021-06-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:XChem group deposition
To Be Published
5S7R
DownloadVisualize
BU of 5s7r by Molmil
XChem group deposition -- Crystal Structure of human ACVR1 in complex with FM010918a
Descriptor: 1,2-ETHANEDIOL, 1lambda~6~,2-thiazetidine-1,1-dione, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, ...
Authors:Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N.
Deposit date:2020-12-11
Release date:2021-06-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:XChem group deposition
To Be Published
5S86
DownloadVisualize
BU of 5s86 by Molmil
XChem group deposition -- Crystal Structure of human ACVR1 in complex with FM010952a
Descriptor: 1,2-ETHANEDIOL, 1-aminocyclopropane-1-carboxamide, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, ...
Authors:Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N.
Deposit date:2020-12-11
Release date:2021-06-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:XChem group deposition
To Be Published
5S80
DownloadVisualize
BU of 5s80 by Molmil
XChem group deposition -- Crystal Structure of human ACVR1 in complex with FM010946a
Descriptor: 1,2-ETHANEDIOL, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, Activin receptor type-1, ...
Authors:Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N.
Deposit date:2020-12-11
Release date:2021-06-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:XChem group deposition
To Be Published
5S7J
DownloadVisualize
BU of 5s7j by Molmil
XChem group deposition -- Crystal Structure of human ACVR1 in complex with FM000893d
Descriptor: 1,2-ETHANEDIOL, 1-[(2R)-oxolan-2-yl]methanamine, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, ...
Authors:Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N.
Deposit date:2020-12-11
Release date:2021-06-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:XChem group deposition
To Be Published
5S77
DownloadVisualize
BU of 5s77 by Molmil
XChem group deposition -- Crystal Structure of human ACVR1 in complex with XS035133b
Descriptor: 1,2-ETHANEDIOL, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, Activin receptor type-1, ...
Authors:Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N.
Deposit date:2020-12-11
Release date:2021-06-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:XChem group deposition
To Be Published
5S7U
DownloadVisualize
BU of 5s7u by Molmil
XChem group deposition -- Crystal Structure of human ACVR1 in complex with FM010938a
Descriptor: (4S)-1-methylimidazolidin-4-amine, 1,2-ETHANEDIOL, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, ...
Authors:Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N.
Deposit date:2020-12-11
Release date:2021-06-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:XChem group deposition
To Be Published
5S7B
DownloadVisualize
BU of 5s7b by Molmil
XChem group deposition -- Crystal Structure of human ACVR1 in complex with FM000329d
Descriptor: (3R)-thiolane-3-carboxylic acid, 1,2-ETHANEDIOL, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, ...
Authors:Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N.
Deposit date:2020-12-11
Release date:2021-06-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:XChem group deposition
To Be Published
5S82
DownloadVisualize
BU of 5s82 by Molmil
XChem group deposition -- Crystal Structure of human ACVR1 in complex with XS035128c
Descriptor: 1,2-ETHANEDIOL, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, Activin receptor type-1, ...
Authors:Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N.
Deposit date:2020-12-11
Release date:2021-06-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:XChem group deposition
To Be Published

224004

PDB entries from 2024-08-21

PDB statisticsPDBj update infoContact PDBjnumon