1LIK
 
 | | STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO ADENOSINE | | 分子名称: | ADENOSINE, CHLORIDE ION, SULFATE ION, ... | | 著者 | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Roos, D.S, Ullman, B, Brennan, R.G. | | 登録日 | 2002-04-17 | | 公開日 | 2002-05-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
J.Mol.Biol., 298, 2000
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1JFS
 | | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX | | 分子名称: | 5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3', HYPOXANTHINE, PURINE NUCLEOTIDE SYNTHESIS REPRESSOR | | 著者 | Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G. | | 登録日 | 2001-06-21 | | 公開日 | 2002-02-08 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor.
Biochemistry, 41, 2002
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1JFT
 | | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX | | 分子名称: | 5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3', HYPOXANTHINE, PHOSPHATE ION, ... | | 著者 | Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G. | | 登録日 | 2001-06-21 | | 公開日 | 2002-02-08 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor.
Biochemistry, 41, 2002
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1JBG
 | | Crystal Structure of MtaN, the Bacillus subtilis Multidrug Transporter Activator, N-terminus | | 分子名称: | transcription activator of multidrug-efflux transporter genes mta | | 著者 | Godsey, M.H, Neyfakh, A.A, Brennan, R.G. | | 登録日 | 2001-06-04 | | 公開日 | 2001-11-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal structure of MtaN, a global multidrug transporter gene activator.
J.Biol.Chem., 276, 2001
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1JLS
 | | STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE URACIL/CPR 2 MUTANT C128V | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Schumacher, M.A, Bashor, C.J, Otsu, K, Zu, S, Parry, R, Ullman, B, Brennan, R.G. | | 登録日 | 2001-07-16 | | 公開日 | 2002-01-16 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1JUP
 | | Crystal structure of the multidrug binding transcriptional repressor QacR bound to malachite green | | 分子名称: | HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, MALACHITE GREEN, SULFATE ION | | 著者 | Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G. | | 登録日 | 2001-08-24 | | 公開日 | 2001-12-12 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural mechanisms of QacR induction and multidrug recognition.
Science, 294, 2001
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1LII
 | | STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO ADENOSINE 2 AND AMP-PCP | | 分子名称: | ADENOSINE, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Roos, D.S, Ullman, B, Brennan, R.G. | | 登録日 | 2002-04-17 | | 公開日 | 2002-05-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
J.Mol.Biol., 298, 2000
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1LIO
 | | STRUCTURE OF APO T. GONDII ADENOSINE KINASE | | 分子名称: | adenosine kinase | | 著者 | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Brennan, R.G. | | 登録日 | 2002-04-17 | | 公開日 | 2002-06-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
J.Mol.Biol., 298, 2000
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1JUS
 | | Crystal structure of the multidrug binding transcriptional repressor QacR bound to rhodamine 6G | | 分子名称: | HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, RHODAMINE 6G, SULFATE ION | | 著者 | Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G. | | 登録日 | 2001-08-27 | | 公開日 | 2001-12-12 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Structural mechanisms of QacR induction and multidrug recognition.
Science, 294, 2001
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1JLR
 | | STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE GTP COMPLEX 2 MUTANT C128V | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, Uracil Phosphoribosyltransferase | | 著者 | Schumacher, M.A, Bashor, C.J, Otsu, K, Zu, S, Parry, R, Ulmman, B, Brennan, R.G. | | 登録日 | 2001-07-16 | | 公開日 | 2002-01-10 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1JT6
 | | Crystal structure of the multidrug binding protein QacR bound to dequalinium | | 分子名称: | DEQUALINIUM, Hypothetical transcriptional regulator IN QACA 5'region, SULFATE ION | | 著者 | Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G. | | 登録日 | 2001-08-20 | | 公開日 | 2001-12-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Structural mechanisms of QacR induction and multidrug recognition.
Science, 294, 2001
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1QVT
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1QCC
 | | CRYSTAL STRUCTURES OF ADENINE PHOSPHORIBOSYLTRANSFERASE FROM LEISHMANIA DONOVANI | | 分子名称: | ADENINE PHOSPHORIBOSYLTRANSFERASE, CITRIC ACID | | 著者 | Phillips, C.L, Ullman, B, Brennan, R.G, Hill, C.P. | | 登録日 | 1999-05-01 | | 公開日 | 1999-07-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani.
EMBO J., 18, 1999
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1QCD
 | | CRYSTAL STRUCTURES OF ADENINE PHOSPHORIBOSYLTRANSFERASE FROM LEISHMANIA DONOVANI | | 分子名称: | ADENINE PHOSPHORIBOSYLTRANSFERASE, SULFATE ION | | 著者 | Phillips, C.L, Ullman, B, Brennan, R.G, Hill, C.P. | | 登録日 | 1999-05-01 | | 公開日 | 1999-07-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani.
EMBO J., 18, 1999
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1QVU
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1SDK
 | | CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A | | 分子名称: | 1,3,5-BENZENETRICARBOXYLIC ACID, CARBON MONOXIDE, HEMOGLOBIN A, ... | | 著者 | Schumacher, M.A, Dixon, M.M, Kluger, R, Jones, R.T, Brennan, R.G. | | 登録日 | 1996-02-26 | | 公開日 | 1996-08-01 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Allosteric transition intermediates modelled by crosslinked haemoglobins.
Nature, 375, 1995
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1SDL
 | | CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A | | 分子名称: | 1,3,5-BENZENETRICARBOXYLIC ACID, CARBON MONOXIDE, HEMOGLOBIN A, ... | | 著者 | Schumacher, M.A, Dixon, M.M, Kluger, R, Jones, R.T, Brennan, R.G. | | 登録日 | 1996-02-26 | | 公開日 | 1996-08-01 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Allosteric transition intermediates modelled by crosslinked haemoglobins.
Nature, 375, 1995
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1PNR
 | | PURINE REPRESSOR-HYPOXANTHINE-PURF-OPERATOR COMPLEX | | 分子名称: | DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR) | | 著者 | Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G. | | 登録日 | 1995-03-29 | | 公開日 | 1995-11-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.
Science, 266, 1994
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1SXH
 | | apo structure of B. megaterium transcription regulator | | 分子名称: | Glucose-resistance amylase regulator | | 著者 | Schumacher, M.A, Allen, G.S, Diel, M, Seidel, G, Hillen, W, Brennan, R.G. | | 登録日 | 2004-03-30 | | 公開日 | 2004-10-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural studies on the apo transcription factor form B. megaterium
Cell(Cambridge,Mass.), 118, 2004
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1QB7
 | | CRYSTAL STRUCTURES OF ADENINE PHOSPHORIBOSYLTRANSFERASE FROM LEISHMANIA DONOVANI. | | 分子名称: | ADENINE, ADENINE PHOSPHORIBOSYLTRANSFERASE, CITRIC ACID, ... | | 著者 | Phillips, C.L, Ullman, B, Brennan, R.G, Hill, C.P. | | 登録日 | 1999-04-30 | | 公開日 | 1999-07-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani.
EMBO J., 18, 1999
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1RKW
 | | CRYSTAL STRUCTURE OF THE MULTIDRUG BINDING TRANSCRIPTIONAL REPRESSOR QACR BOUND TO PENTAMADINE | | 分子名称: | 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, SULFATE ION, Transcriptional regulator qacR | | 著者 | Murray, D.S, Schumacher, M.A, Brennan, R.G. | | 登録日 | 2003-11-23 | | 公開日 | 2004-06-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization.
J.Biol.Chem., 279, 2004
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1RPW
 | | Crystal Structure Of The Multidrug Binding Protein Qacr Bound To The Diamidine Hexamidine | | 分子名称: | 4,4'[1,6-HEXANEDIYLBIS(OXY)]BISBENZENECARBOXIMIDAMIDE, SULFATE ION, Transcriptional regulator qacR | | 著者 | Murray, D.S, Schumacher, M.A, Brennan, R.G. | | 登録日 | 2003-12-03 | | 公開日 | 2004-06-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization.
J.Biol.Chem., 279, 2004
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1SXI
 | | Structure of apo transcription regulator B. megaterium | | 分子名称: | Glucose-resistance amylase regulator, MAGNESIUM ION | | 著者 | Schumacher, M.A, Allen, G.S, Diel, M, Seidel, G, Hillen, W, Brennan, R.G. | | 登録日 | 2004-03-30 | | 公開日 | 2004-10-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural studies on the apo transcription factor form B. megaterium
Cell(Cambridge,Mass.), 118, 2004
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1SXG
 | | Structural studies on the apo transcription factor form B. megaterium | | 分子名称: | 2-PHENYLAMINO-ETHANESULFONIC ACID, Glucose-resistance amylase regulator | | 著者 | Schumacher, M.A, Allen, G.S, Diel, M, Seidel, G, Hillen, W, Brennan, R.G. | | 登録日 | 2004-03-30 | | 公開日 | 2004-10-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural studies on the apo transcription factor form B. megaterium
Cell(Cambridge,Mass.), 118, 2004
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1RZR
 | | crystal structure of transcriptional regulator-phosphoprotein-DNA complex | | 分子名称: | 5'-D(*CP*TP*GP*AP*AP*AP*GP*CP*GP*CP*TP*AP*AP*CP*AP*G)-3', 5'-D(*CP*TP*GP*TP*TP*AP*GP*CP*GP*CP*TP*TP*TP*CP*AP*G)-3', Glucose-resistance amylase regulator, ... | | 著者 | Schumacher, M.A, Allen, G.S, Brennan, R.G. | | 登録日 | 2003-12-27 | | 公開日 | 2004-10-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for allosteric control of the transcription regulator CcpA by the phosphoprotein HPr-Ser46-P.
Cell(Cambridge,Mass.), 118, 2004
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