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PDB: 157 件
4Z59
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BU of 4z59 by Molmil
HipB-O4 20mer complex
分子名称: Antitoxin HipB, DNA (5'-D(*TP*TP*AP*TP*CP*CP*GP*CP*GP*AP*TP*CP*GP*CP*GP*GP*AP*TP*AP*A)-3')
著者Min, J, Brennan, R.G, Schumacher, M.A.
登録日2015-04-02
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular mechanism on hipBA gene regulation.
To be published
4Z5C
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BU of 4z5c by Molmil
HipB-O3 21mer complex
分子名称: Antitoxin HipB, DNA (5'-D(*TP*TP*TP*AP*TP*CP*CP*CP*GP*TP*AP*GP*AP*GP*CP*GP*GP*AP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*TP*AP*CP*GP*GP*GP*AP*TP*A)-3')
著者Min, J, Brennan, R.G, Schumacher, M.A.
登録日2015-04-02
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular mechanism on hipBA gene regulation.
To be published
1PNR
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BU of 1pnr by Molmil
PURINE REPRESSOR-HYPOXANTHINE-PURF-OPERATOR COMPLEX
分子名称: DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR)
著者Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G.
登録日1995-03-29
公開日1995-11-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.
Science, 266, 1994
1QB7
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BU of 1qb7 by Molmil
CRYSTAL STRUCTURES OF ADENINE PHOSPHORIBOSYLTRANSFERASE FROM LEISHMANIA DONOVANI.
分子名称: ADENINE, ADENINE PHOSPHORIBOSYLTRANSFERASE, CITRIC ACID, ...
著者Phillips, C.L, Ullman, B, Brennan, R.G, Hill, C.P.
登録日1999-04-30
公開日1999-07-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani.
EMBO J., 18, 1999
1QVU
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BU of 1qvu by Molmil
Crystal structure of the multidrug binding transcriptional repressor QacR bound to two drugs: ethidium and proflavine
分子名称: ETHIDIUM, PROFLAVIN, Transcriptional regulator qacR
著者Schumacher, M.A, Miller, M.C, Brennan, R.G.
登録日2003-08-28
公開日2004-08-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein
Embo J., 23, 2004
1SDL
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BU of 1sdl by Molmil
CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A
分子名称: 1,3,5-BENZENETRICARBOXYLIC ACID, CARBON MONOXIDE, HEMOGLOBIN A, ...
著者Schumacher, M.A, Dixon, M.M, Kluger, R, Jones, R.T, Brennan, R.G.
登録日1996-02-26
公開日1996-08-01
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Allosteric transition intermediates modelled by crosslinked haemoglobins.
Nature, 375, 1995
1SXI
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BU of 1sxi by Molmil
Structure of apo transcription regulator B. megaterium
分子名称: Glucose-resistance amylase regulator, MAGNESIUM ION
著者Schumacher, M.A, Allen, G.S, Diel, M, Seidel, G, Hillen, W, Brennan, R.G.
登録日2004-03-30
公開日2004-10-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural studies on the apo transcription factor form B. megaterium
Cell(Cambridge,Mass.), 118, 2004
1SXG
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BU of 1sxg by Molmil
Structural studies on the apo transcription factor form B. megaterium
分子名称: 2-PHENYLAMINO-ETHANESULFONIC ACID, Glucose-resistance amylase regulator
著者Schumacher, M.A, Allen, G.S, Diel, M, Seidel, G, Hillen, W, Brennan, R.G.
登録日2004-03-30
公開日2004-10-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural studies on the apo transcription factor form B. megaterium
Cell(Cambridge,Mass.), 118, 2004
1SXH
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BU of 1sxh by Molmil
apo structure of B. megaterium transcription regulator
分子名称: Glucose-resistance amylase regulator
著者Schumacher, M.A, Allen, G.S, Diel, M, Seidel, G, Hillen, W, Brennan, R.G.
登録日2004-03-30
公開日2004-10-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural studies on the apo transcription factor form B. megaterium
Cell(Cambridge,Mass.), 118, 2004
1SDK
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BU of 1sdk by Molmil
CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A
分子名称: 1,3,5-BENZENETRICARBOXYLIC ACID, CARBON MONOXIDE, HEMOGLOBIN A, ...
著者Schumacher, M.A, Dixon, M.M, Kluger, R, Jones, R.T, Brennan, R.G.
登録日1996-02-26
公開日1996-08-01
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Allosteric transition intermediates modelled by crosslinked haemoglobins.
Nature, 375, 1995
2NZV
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BU of 2nzv by Molmil
Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors G6P and FBP
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, Catabolite control protein, Phosphocarrier protein HPr, ...
著者Schumacher, M.A, Hillen, W, Brennan, R.G.
登録日2006-11-25
公開日2007-05-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Mechanism for the Fine-tuning of CcpA Function by The Small Molecule Effectors Glucose 6-Phosphate and Fructose 1,6-Bisphosphate.
J.Mol.Biol., 368, 2007
2NZU
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BU of 2nzu by Molmil
Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors G6P and FBP
分子名称: 6-O-phosphono-beta-D-glucopyranose, Catabolite control protein, Phosphocarrier protein HPr, ...
著者Schumacher, M.A, Hillen, W, Brennan, R.G.
登録日2006-11-25
公開日2007-05-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Mechanism for the Fine-tuning of CcpA Function by The Small Molecule Effectors Glucose 6-Phosphate and Fructose 1,6-Bisphosphate.
J.Mol.Biol., 368, 2007
1RZR
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BU of 1rzr by Molmil
crystal structure of transcriptional regulator-phosphoprotein-DNA complex
分子名称: 5'-D(*CP*TP*GP*AP*AP*AP*GP*CP*GP*CP*TP*AP*AP*CP*AP*G)-3', 5'-D(*CP*TP*GP*TP*TP*AP*GP*CP*GP*CP*TP*TP*TP*CP*AP*G)-3', Glucose-resistance amylase regulator, ...
著者Schumacher, M.A, Allen, G.S, Brennan, R.G.
登録日2003-12-27
公開日2004-10-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for allosteric control of the transcription regulator CcpA by the phosphoprotein HPr-Ser46-P.
Cell(Cambridge,Mass.), 118, 2004
2OEN
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BU of 2oen by Molmil
Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors glucose-6-phosphate and fructose-1,6-bisphosphate
分子名称: Catabolite control protein, Phosphocarrier protein HPr
著者Schumacher, M.A, Seidel, G, Hillen, W, Brennan, R.G.
登録日2006-12-30
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Structural Mechanism for the Fine-tuning of CcpA Function by The Small Molecule Effectors Glucose 6-Phosphate and Fructose 1,6-Bisphosphate.
J.Mol.Biol., 368, 2007
1RPW
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BU of 1rpw by Molmil
Crystal Structure Of The Multidrug Binding Protein Qacr Bound To The Diamidine Hexamidine
分子名称: 4,4'[1,6-HEXANEDIYLBIS(OXY)]BISBENZENECARBOXIMIDAMIDE, SULFATE ION, Transcriptional regulator qacR
著者Murray, D.S, Schumacher, M.A, Brennan, R.G.
登録日2003-12-03
公開日2004-06-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization.
J.Biol.Chem., 279, 2004
1RKW
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BU of 1rkw by Molmil
CRYSTAL STRUCTURE OF THE MULTIDRUG BINDING TRANSCRIPTIONAL REPRESSOR QACR BOUND TO PENTAMADINE
分子名称: 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, SULFATE ION, Transcriptional regulator qacR
著者Murray, D.S, Schumacher, M.A, Brennan, R.G.
登録日2003-11-23
公開日2004-06-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization.
J.Biol.Chem., 279, 2004
1UPF
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BU of 1upf by Molmil
STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V BOUND TO THE DRUG 5-FLUOROURACIL
分子名称: 5-FLUOROURACIL, SULFATE ION, URACIL PHOSPHORIBOSYLTRANSFERASE
著者Schumacher, M.A, Carter, D, Scott, D, Roos, D, Ullman, B, Brennan, R.G.
登録日1998-06-17
公開日1999-06-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
EMBO J., 17, 1998
1UPU
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BU of 1upu by Molmil
STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V, BOUND TO PRODUCT URIDINE-1-MONOPHOSPHATE (UMP)
分子名称: PHOSPHATE ION, URACIL PHOSPHORIBOSYLTRANSFERASE, URIDINE-5'-MONOPHOSPHATE
著者Schumacher, M.A, Carter, D, Scott, D, Roos, D, Ullman, B, Brennan, R.G.
登録日1998-04-16
公開日1999-05-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
EMBO J., 17, 1998
1VPW
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BU of 1vpw by Molmil
STRUCTURE OF THE PURR MUTANT, L54M, BOUND TO HYPOXANTHINE AND PURF OPERATOR DNA
分子名称: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), HYPOXANTHINE, PURINE REPRESSOR
著者Arvidson, D.N, Lu, F, Faber, C, Zalkin, H, Brennan, R.G.
登録日1998-02-27
公開日1998-06-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure of PurR mutant L54M shows an alternative route to DNA kinking.
Nat.Struct.Biol., 5, 1998
1DBQ
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BU of 1dbq by Molmil
DNA-BINDING REGULATORY PROTEIN
分子名称: MAGNESIUM ION, PURINE REPRESSOR
著者Schumacher, M.A, Choi, K.Y, Lu, F, Zalkin, H, Brennan, R.G.
登録日1996-02-13
公開日1996-12-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mechanism of corepressor-mediated specific DNA binding by the purine repressor.
Cell(Cambridge,Mass.), 83, 1995
1EXJ
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BU of 1exj by Molmil
CRYSTAL STRUCTURE OF TRANSCRIPTION ACTIVATOR BMRR, FROM B. SUBTILIS, BOUND TO 21 BASE PAIR BMR OPERATOR AND TPP
分子名称: DNA (5'-D(*AP*CP*CP*CP*TP*CP*CP*CP*CP*TP*TP*AP*GP*GP*GP*GP*AP*GP*GP*GP*T)-3'), MULTIDRUG-EFFLUX TRANSPORTER REGULATOR, SODIUM ION, ...
著者Zheleznova-Heldwein, E.E, Brennan, R.G.
登録日2000-05-02
公開日2001-01-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the transcription activator BmrR bound to DNA and a drug.
Nature, 409, 2001
1EXI
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BU of 1exi by Molmil
CRYSTAL STRUCTURE OF TRANSCRIPTION ACTIVATOR BMRR, FROM B. SUBTILIS, BOUND TO 21 BASE PAIR BMR OPERATOR AND TPSB
分子名称: DNA (5'-D(*AP*CP*CP*CP*TP*CP*CP*CP*CP*TP*TP*AP*GP*GP*GP*GP*AP*GP*GP*GP*T)-3'), MULTIDRUG-EFFLUX TRANSPORTER REGULATOR, TETRAPHENYLANTIMONIUM ION, ...
著者Zheleznova-Heldwein, E.E, Brennan, R.G.
登録日2000-05-02
公開日2001-01-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Crystal structure of the transcription activator BmrR bound to DNA and a drug.
Nature, 409, 2001
1DH3
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BU of 1dh3 by Molmil
CRYSTAL STRUCTURE OF A CREB BZIP-CRE COMPLEX REVEALS THE BASIS FOR CREB FAIMLY SELECTIVE DIMERIZATION AND DNA BINDING
分子名称: DNA (5'-D(*CP*CP*TP*TP*GP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*CP*AP*AP*G)-3'), MAGNESIUM ION, TRANSCRIPTION FACTOR CREB
著者Schumacher, M.A, Goodman, R.H, Brennan, R.G.
登録日1999-11-27
公開日2000-11-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding
J.Biol.Chem., 275, 2000
1DBR
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BU of 1dbr by Molmil
HYPOXANTHINE GUANINE XANTHINE
分子名称: HYPOXANTHINE GUANINE XANTHINE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION
著者Schumacher, M.A, Carter, D, Roos, D, Ullman, B, Brennan, R.G.
登録日1996-02-13
公開日1997-12-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loop.
Nat.Struct.Biol., 3, 1996
4NL2
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BU of 4nl2 by Molmil
Crystal Structure of Listeria monocytogenes Hfq
分子名称: Protein hfq, S-1,2-PROPANEDIOL
著者Kovach, A.R, Brennan, R.G.
登録日2013-11-13
公開日2014-09-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Recognition of U-rich RNA by Hfq from the Gram-positive pathogen Listeria monocytogenes.
Rna, 20, 2014

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